Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ikuo Imazeki"'
Autor:
Toshifumi Sakaguchi, Kazuhiro Shiizaki, Fumie Saji, Tadao Akizawa, Shigeaki Kato, Eiji Kusano, Eiko Nakazawa, Yoshiyuki Moriguchi, Ikuo Imazeki, Ikuji Hatamura
Publikováno v:
Bone. 45:964-971
Vitamin D plays a major role in mineral and skeletal homeostasis through interaction with the nuclear vitamin D receptor (VDR) of target cells. Recent reports have indicated that some cellular effects of vitamin D may occur via alternative signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e808474f7d64d698aa7a76585e1f6676
https://doi.org/10.1016/j.bone.2009.07.013
https://doi.org/10.1016/j.bone.2009.07.013
Autor:
Takashi Shigematsu, Shigeo Negi, Ikuo Imazeki, Ikuji Hatamura, Eiji Kusano, Fumie Saji, Kazuhiro Shiizaki, Tadao Akizawa, Toshifumi Sakaguchi
Publikováno v:
Nephrology Dialysis Transplantation. 23:1529-1536
Controlling hyperplasia of the parathyroid gland (PTG) is important in the management of secondary hyperparathyroidism (SHPT). Regression of the hyperplastic PTG requires a decrease in the number of parathyroid cells (PTCs), so the present study inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6039aed80347f8a80db000aff7ceb1
https://doi.org/10.1093/ndt/gfm850
https://doi.org/10.1093/ndt/gfm850
Autor:
Toshifumi Sakaguchi, Tadashi Okada, Shigeo Negi, Ikuo Imazeki, Naohiko Hayakawa, Tadao Akizawa, Ikuji Hatamura, Kazuhiro Shiizaki, Takashi Shigematsu
Publikováno v:
Nephrology Dialysis Transplantation. 22:1078-1086
Background. Injection of maxacalcitol (OCT) directly into the parathyroid gland (PTG) is a clinically safe and effective treatment for advanced secondary hyperparathyroidism (A-SHPT) resistant to conventional medical treatment. In the present study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740e7d2c6b283bec82a5c5c5ff052c57
https://doi.org/10.1093/ndt/gfl713
https://doi.org/10.1093/ndt/gfl713
Autor:
Fumie Saji, Shigeo Negi, Ken Kunimoto, Kazuhiro Shiizaki, Ikuo Imazeki, Tadao Akizawa, Yasuteru Muragaki, Ikuji Hatamura, Toshifumi Sakaguchi, Masanori Okamoto
Publikováno v:
Kidney International. 70(3):486-495
Direct maxacalcitol (OCT) injection into a parathyroid gland (PTG) ameliorates several important etiologic factors of resistance to medical treatments for secondary hyperparathyroidism (s-HPT): the upregulations of vitamin D receptor (VDR) and Ca-sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4185228eca6bf4db8d3f6c33a0dc2ca6
Autor:
Takemasa Tsuji, Ikuo Imazeki, Junko Matsuzaki, Yue Zhang, Tomoaki Sakai, Hiroaki Ikeda, Takashi Nishimura, Daiko Wakita
Publikováno v:
Cancer Science. 97:139-147
Various dendritic cell subsets are induced from bone marrow cells under different cytokine conditions. We have demonstrated previously that the Th1-cytokine-conditioned bone marrow-derived dendritic cell (BMDC) subset BMDC1 (generated in the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecceac3bfeb669079aeaabf794c97e10
https://doi.org/10.1111/j.1349-7006.2006.00144.x
https://doi.org/10.1111/j.1349-7006.2006.00144.x
Publikováno v:
Biomedical Research. 27:1-9
1 alpha,25-dihydroxyvitamin D3 [Calcitriol or 1,25(OH)(2)D(3)] is an important active metabolite involved in multiple functions but its calcemic effect in vivo limits its therapeutic applications. On the other hand, 22-oxa-1 alpha,25-dihydroxyvitamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ef8dae1f56769a883d6fd638f5176b
https://doi.org/10.2220/biomedres.27.1
https://doi.org/10.2220/biomedres.27.1
Publikováno v:
Autoimmunity. 38:369-375
Immune balance controlled by Th1 and Th2 cells is critical for the protection of host from pathogenic invasion while its imbalance becomes the cause of various immune disorders including autoimmune diseases. Cytokines, such as IL-12 and IL-4, are cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1958a6cffaa5d75ff9ca070013b1b530
https://doi.org/10.1080/08916930500124122
https://doi.org/10.1080/08916930500124122
Autor:
Ikuji Hatamura, Akira Ooshima, Shigeo Negi, Toshifumi Sakaguchi, Tadao Akizawa, Kazuhiro Shiizaki, Fumie Saji, Masahide Mizobuchi, Ikuo Imazeki, Ken Kunimoto
Publikováno v:
Journal of the American Society of Nephrology. 16:97-108
The most important etiological factors of resistance to medical treatments for secondary hyperparathyroidism are the decreased contents of the vitamin D receptor (VDR) and Ca-sensing receptor (CaSR) in parathyroid cells and a severely swollen parathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b671be2041817d65369ba1f52e888974
https://doi.org/10.1681/asn.2004030236
https://doi.org/10.1681/asn.2004030236
Autor:
Ikuo Imazeki
Publikováno v:
Folia Pharmacologica Japonica. 121:65-75
Maxacalcitol (Oxarol) is a derivative of vitamin D compounds applied for the secondary hyperparathyroidism (2 degrees HPT) of hemodialysis (HD) patients as an injection and psoriasis as an ointment. 2 degrees HPT is one of the complications in HD pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ff513a3697e5514cfe1e8b489454be
https://doi.org/10.1254/fpj.121.65
https://doi.org/10.1254/fpj.121.65
Autor:
Jun-ichi Miyazaki, Yasuko Ishikawa, Junichiro James Kazama, Yoshiyuki Moriguchi, Noboru Higuchi, Makoto Sugawa, Fumitake Gejyo, Ikuo Imazeki, Ken Ataka, Hiroki Maruyama, Susumu Hasegawa, Yumi Ito
Publikováno v:
Human Gene Therapy. 11:429-437
It has been demonstrated that gene transfer by in vivo electroporation of mouse muscle increases the level of gene expression by more than 100-fold over simple plasmid DNA injection. We tested continuous rat erythropoietin (Epo) delivery by this meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6352b24919f203350b57652e59da8c6
https://doi.org/10.1089/10430340050015897
https://doi.org/10.1089/10430340050015897