Výsledky vyhledávání - "Ikuo, Kawamura"

Akademický článek

Anti-Aging Effects of Polyoxometalates on Skin

Autor: Katsuyuki Fujinami, Katsuaki Dan, Toshiko Tanaka-Kagawa, Ikuo Kawamura

Publikováno v: Applied Sciences, Vol 11, Iss 24, p 11948 (2021)

Excessive reactive oxygen species (ROS) generation by inflammation and glycation contributes to various aging-related changes in the body. Therefore, inhibiting ROS production can prevent wrinkles, maculae, dullness, and slackness in skin. To assess

Externí odkaz: https://doaj.org/article/b70c6d6c0b1e4f4dac9ce2662831af48

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ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism

Autor: Ikuo Kawamura, Kohsuke Tsuchiya, Shunsuke Sakai, Ryosuke Uchiyama, Hideki Hara, Masao Mitsuyama, Takashi Suda, Rendong Fang, Hiroko Tsutsui

Publikováno v: Mucosal immunology. 12(5)

It is widely accepted that inflammasomes protect the host from microbial pathogens by inducing inflammatory responses through caspase-1 activation. Here, we show that the inflammasome components ASC and NLRP3 are required for resistance to pneumococc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10df0b29c1da9a4db9f87c819bca2d0
https://pubmed.ncbi.nlm.nih.gov/31278375

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Serum Syndecan-4 as a Possible Biomarker in Patients With Acute Pneumonia

Autor: Ikuo Kawamura, Yuki Sato, Yuichi Endo, Yasuhito Suzuki, Mitsuru Munakata, Tetsuhito Kojima, Manabu Uematsu, Kohsuke Tsuchiya, Charles W. Frevert, Atsuro Fukuhara, Naoko Fukuhara, Suguru Sato, Mishie Tanino, Yoshinori Tanino, Xintao Wang, Kenichi Misa, Takefumi Nikaido

Publikováno v: Journal of Infectious Diseases. 212:1500-1508

BACKGROUND Syndecan-4 is a transmembrane heparan sulfate proteoglycan expressed in a variety of cells, and glycosaminoglycan side chains of syndecan-4 bind to several proteins, suggesting several biological functions. However, the role of syndecan-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e8fd88cdf6ac06bf04eba3c1f0ffa9
https://doi.org/10.1093/infdis/jiv234

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The adaptor ASC exacerbates lethalListeria monocytogenesinfection by mediating IL-18 production in an inflammasome-dependent and -independent manner

Autor: Eduardo Hernandez-Cuellar, Sylvia Daim, Huixin Qu, Hideki Hara, Kohsuke Tsuchiya, Shunsuke Sakai, Ikuo Kawamura, Xi Chen, Sita R. Dewamitta, Masao Mitsuyama, Rendong Fang

Publikováno v: European Journal of Immunology. 44:3696-3707

Listeria monocytogenes induces the formation of inflammasomes and subsequent caspase-1 activation, and the adaptor apoptosis-associated speck-like protein containing a CARD (ASC) is crucial for this response. However, the role of ASC in L. monocytoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0067a9b8106e1b071fb5cce00f2fa205
https://doi.org/10.1002/eji.201444673

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Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection

Autor: Rendong Fang, Kohsuke Tsuchiya, Shunsuke Sakai, Eduardo Hernandez-Cuellar, Ikuo Kawamura, Hideki Hara, Masao Mitsuyama

Publikováno v: Infection and Immunity. 82:2310-2317

Streptococcus pneumoniae , a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f318c45b830e1a0097723e4ea7d4a857
https://doi.org/10.1128/iai.01572-14

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