Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ikuko Yamada"'
Autor:
Masato Uemura, Tamio Furuse, Ikuko Yamada, Tomoko Kushida, Takaya Abe, Keiko Imai, Soichi Nagao, Moeko Kudoh, Katsuhiko Yoshizawa, Masaru Tamura, Hiroshi Kiyonari, Shigeharu Wakana, Shinji Hirano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Protocadherin 9 (Pcdh9) is a member of the cadherin superfamily and is uniquely expressed in the vestibular and limbic systems; however, its physiological role remains unclear. Here, we studied the expression of Pcdh9 in the limbic system an
Externí odkaz:
https://doaj.org/article/aae1078fad7b415d9b5eaa507b8b9587
Autor:
Kensuke Matsumura, Kaoru Seiriki, Shota Okada, Masashi Nagase, Shinya Ayabe, Ikuko Yamada, Tamio Furuse, Hirotoshi Shibuya, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Kazuki Nagayasu, Kana Yamamoto, Kohei Kitagawa, Hiroki Miura, Nanaka Gotoda-Nishimura, Hisato Igarashi, Misuzu Hayashida, Masayuki Baba, Momoka Kondo, Shigeru Hasebe, Kosei Ueshima, Atsushi Kasai, Yukio Ago, Atsuko Hayata-Takano, Norihito Shintani, Tokuichi Iguchi, Makoto Sato, Shun Yamaguchi, Masaru Tamura, Shigeharu Wakana, Atsushi Yoshiki, Ayako M. Watabe, Hideyuki Okano, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
De novo mutations significantly contribute to autism spectrum disorders (ASD). Here, the authors demonstrate that ASD-associated de novo mutations in the POGZ gene, one of a high-confidence ASD gene, lead to ASD-related impaired neuronal development
Externí odkaz:
https://doaj.org/article/b3970c6881ab49c4a520b80ed0ce7f6e
Autor:
Takafumi Hara, Ikuko Yamada, Takuto Ohashi, Masaru Tamura, Atsushi Hijikata, Takashi Watanabe, Minghao Gao, Kana Ito, Saeko Kawamata, Shiori Azuma, Emi Yoshigai, Yukiko Sumiyoshi, Natsumi Yasuhiro, Osamu Ohara, Heloísa G Dos Santos, Toshiyuki Fukada
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276452 (2022)
Zinc plays a critical role in many physiological processes, and disruption of zinc homeostasis induces various disorders, such as growth retardation, osteopenia, immune deficiency, and inflammation. However, how the imbalance in zinc homeostasis lead
Externí odkaz:
https://doaj.org/article/fe8a6be096984458be8a07a08c403147
Autor:
Tamio Furuse, Hiroshi Mizuma, Yuuki Hirose, Tomoko Kushida, Ikuko Yamada, Ikuo Miura, Hiroshi Masuya, Hiromasa Funato, Masashi Yanagisawa, Hirotaka Onoe, Shigeharu Wakana
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Dysfunction of glucose transporter 1 (GLUT1) proteins causes infantile epilepsy, which is designated as a GLUT1 deficiency syndrome (GLUT1DS; OMIM #606777). Patients with GLUT1DS display varied clinical phenotypes, such as infantile seizures, ataxia,
Externí odkaz:
https://doaj.org/article/cc49a2714ee7442fb81f77b38aa7c057
Autor:
Masahito Irie, Masanobu Yoshikawa, Ryuichi Ono, Hirotaka Iwafune, Tamio Furuse, Ikuko Yamada, Shigeharu Wakana, Yui Yamashita, Takaya Abe, Fumitoshi Ishino, Tomoko Kaneko-Ishino
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005521 (2015)
Gene targeting of mouse Sushi-ichi-related retrotransposon homologue 11/Zinc finger CCHC domain-containing 16 (Sirh11/Zcchc16) causes abnormal behaviors related to cognition, including attention, impulsivity and working memory. Sirh11/Zcchc16 encodes
Externí odkaz:
https://doaj.org/article/808d7aa96ac942c0b8f25f169af38986
Autor:
Tetsuya Hirata, Atsushi Kobayashi, Tamio Furuse, Ikuko Yamada, Masaru Tamura, Hiroyuki Tomita, Yuko Tokoro, Akinori Ninomiya, Yoshitaka Fujihara, Masahito Ikawa, Yusuke Maeda, Yoshiko Murakami, Yasuhiko Kizuka, Taroh Kinoshita
Publikováno v:
The Journal of biological chemistry. 298(3)
Glycosylphosphatidylinositol (GPI) is a posttranslational glycolipid modification of proteins that anchors proteins in lipid rafts on the cell surface. Although some GPI-anchored proteins (GPI-APs), including the prion protein PrP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b327fd6b37089db66ad22448668ddf
https://pubmed.ncbi.nlm.nih.gov/35151686
https://pubmed.ncbi.nlm.nih.gov/35151686
Autor:
Shigenaru Wakana, Yasunori Hayashi, Meiko Kawamura, Ken Miya, Kenji Sakimura, Tamio Furuse, Hiroto Kojima, Akio Suzuki, Karam Kim, Manabu Abe, Ikuko Yamada
Publikováno v:
Neurobiology of Learning and Memory. 157:86-95
CaMKII is a pivotal kinase that plays essential roles in synaptic plasticity. Apart from its signaling function, the structural function of CaMKII is becoming clear. CaMKII - F-actin interaction stabilizes actin cytoskeleton in a dendritic spine. A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f1725595e8a156e21a4e8523194581
https://doi.org/10.1016/j.nlm.2018.12.003
https://doi.org/10.1016/j.nlm.2018.12.003
Publikováno v:
Bulletin of Volcanology. 82
The sudden destabilization of voluminous magma after stable accumulation in a crustal magma chamber is a key process in the sequence of a catastrophic caldera-forming eruption. We investigated the petrological characteristics of magma that has erupte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2224cec424a701eb4d54e231f076e12f
https://doi.org/10.1007/s00445-020-01384-6
https://doi.org/10.1007/s00445-020-01384-6
Autor:
Masaru Tamura, Atsuko Hayata-Takano, Shun Yamaguchi, Hisato Igarashi, Misuzu Hayashida, Masayuki Baba, Hitoshi Hashimoto, Hiroki Miura, Tamio Furuse, Hidenaga Yamamori, Michiko Fujimoto, Hideyuki Okano, Shigeru Hasebe, Ikuko Yamada, Kosei Ueshima, M. Kondo, Kaoru Seiriki, Kana Yamamoto, Takanobu Nakazawa, Atsushi Kasai, Kensuke Matsumura, Shinya Ayabe, Ayako M. Watabe, Shota Okada, Kohei Kitagawa, Yuka Yasuda, Atsushi Yoshiki, Masashi Nagase, Makoto Sato, Hirotoshi Shibuya, Yukio Ago, Ryota Hashimoto, Norihito Shintani, Kazuhiro Takuma, Nanaka Gotoda-Nishimura, Shigeharu Wakana, Kazuki Nagayasu, Tokuichi Iguchi
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Pogo transposable element derived with ZNF domain (POGZ) has been identified as one of the most recurrently de novo mutated genes in patients with neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD), intellectual disability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aea5494bb088edf996ea9fc1cda0f34
http://europepmc.org/articles/PMC7044294
http://europepmc.org/articles/PMC7044294
Autor:
Hiroshi Mizuma, Shigeharu Wakana, Masashi Yanagisawa, Hirotaka Onoe, Hiroshi Masuya, Hiromasa Funato, Tomoko Kushida, Yuuki Hirose, Ikuo Miura, Tamio Furuse, Ikuko Yamada
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Dysfunction of glucose transporter 1 (GLUT1) proteins causes infantile epilepsy, which is designated as a GLUT1 deficiency syndrome (GLUT1DS; OMIM #606777). Patients with GLUT1DS display varied clinical phenotypes, such as infantile seizures, ataxia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5d1122d9c02fa3403a0c2d5cc822a2
http://europepmc.org/articles/PMC6765196
http://europepmc.org/articles/PMC6765196