Výsledky vyhledávání - "Ikuko Tsujimoto"

Apoptosis Signal-Regulating Kinase 1/p38 Signaling Pathway Negatively Regulates Physiological Hypertrophy

Autor: Kazuhiko Nishida, Yoshiharu Higuchi, Shigemiki Omiya, Toshihiro Takeda, Shungo Hikoso, Isamu Mizote, Yasushi Matsumura, Masayuki Taniike, Ikuko Tsujimoto, Atsuko Nakai, Kinya Otsu, Hidenori Ichijo, Yuko Nakano, Osamu Yamaguchi, Masatsugu Hori

Publikováno v: Circulation. 117:545-552

Background— Mechanical stress on the heart can lead to crucially different outcomes. Physiological stimuli such as exercise cause adaptive cardiac hypertrophy, characterized by a normal cardiac structure and normal or enhanced cardiac function. Pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf989818e3d2e2ee330552f3952447f
https://doi.org/10.1161/circulationaha.107.710434

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Ca2+-sensitive tyrosine kinase Pyk2/CAK β-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy

Autor: Kazuhiko Nishida, Hiroyuki Nakayama, Michio Asahi, Shungo Hikoso, Masatsugu Hori, Toshihiro Takeda, Tetsuya Watanabe, Yoshiharu Higuchi, Masayuki Taniike, Osamu Yamaguchi, Kazunori Kashiwase, Yasushi Matsumura, Ikuko Tsujimoto, Shinichi Hirotani, Kinya Otsu, Terukatsu Sasaki

Publikováno v: Journal of Molecular and Cellular Cardiology. 36:799-807

G-protein-coupled receptor agonists including endothelin-1 (ET-1) and phenylephrine (PE) induce hypertrophy in neonatal ventricular cardiomyocytes. Others and we previously reported that Rac1 signaling pathway plays an important role in this agonist-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4a71b22ea0978e2d6ae785b6a15433
https://doi.org/10.1016/j.yjmcc.2004.03.002

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Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Autor: Masahiro Nakamura, Akira Kikuchi, Kensaku Shojima, Hideaki Hanaki, Ikuko Tsujimoto, Akira Sato, Kazunari Hattori, Hideki Yamamoto, Keiji Dohi, Yuji Sato, Michinari Hirata

Publikováno v: Scientific Reports

Wnt5a activates the Wnt/β-catenin-independent pathway and its overexpression is associated with tumor aggressiveness enhancing invasive activity. For this action, Wnt5a-induced receptor endocytosis with clathrin is required. Wnt5a expression was pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68056d8015affc8616538d7a3461cfe0
https://pubmed.ncbi.nlm.nih.gov/25622531

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General anaesthesia with and without intubation for patients with Cornelia de Lange syndrome

Autor: Junichiro Kotani, Yoshinao Asahi, Ikuko Tsujimoto, Yusuke Kawai, Shiro Omichi, Takahiro Suzuki, Mikihiko Kogo, Masahiro Sugimoto

Publikováno v: Southern African Journal of Anaesthesia and Analgesia; Vol 15, No 4 (2009); 32-34

We present the use of different methods of general anaesthesia in two patients with Cornelia de Lange syndrome and its contribution to the patients’ oral health.Case 1: The patient was a 22-year-old woman with Cornelia de Lange syndrome who underwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1843e7b008c66962b90b0c0442ce01a
https://doi.org/10.1080/22201173.2009.10872614

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The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms

Autor: Hideki, Yamamoto, Chihiro, Awada, Hideaki, Hanaki, Hiroshi, Sakane, Ikuko, Tsujimoto, Yuko, Takahashi, Toshifumi, Takao, Akira, Kikuchi

Publikováno v: Journal of cell science. 126(Pt 13)

Wnts are glycan- and lipid-modified morphogens that are important for cellular responses, but how Wnts are secreted in polarized epithelial cells remains unclear. Although Wntless (Wls) has been shown to interact with Wnts and support their secretion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c17ab24c7efb73d4c23b1bbca10c579e
https://pubmed.ncbi.nlm.nih.gov/23613470

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Apicobasal secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms

Autor: Hideaki Hanaki, Chihiro Awada, Hiroshi Sakane, Ikuko Tsujimoto, Hideki Yamamoto, Toshifumi Takao, Yuko Takahashi, Akira Kikuchi

Publikováno v: Journal of Cell Science.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8d49ac4dce7c928abe9c9131fc2c4fe
https://doi.org/10.1242/jcs.126052

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