Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ikuko Takasaki"'
Autor:
Toshikazu Kubo, Mitsuru Akashi, Tsutomu Furuzono, Isao Kitajima, Satoshi Sakoda, Hiroshi Shin, Ikuko Takasaki, Akio Kishida, Katsuyo Yamaji, Eiichi Nagaoka, Ikuro Maruyama
Publikováno v:
Pathophysiology. 6:63-69
Mechanical stimulation of osteoblasts has been shown to induce changes in phenotype at the cellular level. The cellular changes resulting from the mechanical stretching of human osteoblast-like cells (MG-63) cultured on flexible silicone-coated films
Autor:
Takeshi Tokioka, Ikuro Maruyama, Toshikazu Kubo, Ikuko Takasaki, Toshihiro Nakajima, Naohiro Hanyu, Isao Kitajima, Qing Shao, Hiroshi Shin
Publikováno v:
Annals of the Rheumatic Diseases. 58:55-60
OBJECTIVE—To clarify the mechanism of thrombin receptor mediated signal transduction and the induction of cytokines by thrombin stimulation in rheumatoid synovial fibroblasts. METHODS—Cytokines were measured by enzyme linked immunosorbent assay (
Publikováno v:
Bone. 19(3)
Osteoblasts are affected by TNF-alpha overproduction by immune cells during inflammation. We demonstrate that apoptosis is induced in murine osteoblastic MC3T3-E1 cells by exceeding the concentrations 100 units/mL of TNF-alpha and 10 mumol/L of synth
Autor:
Ikuko Takasaki, Y. Yamashita, Isao Kitajima, Toshihiro Nakajima, Takeshi Tokioka, Yasuko Soejima, Ikuro Maruyama, K. Shigeta, Hiroshi Shin, Kazuhiro Abeyama
Publikováno v:
Biochemical and biophysical research communications. 204(2)
A thrombin receptor has been cloned and is thought to mediate a variety of thrombin-induced responses. However, the transcription factors important for postreceptor signaling have been little clarified. The post-receptor signals are mediated by sever
Autor:
ISAO KITAJIMA, ICHIRO SEMBA, TAKENORI NOIKURA, KAZUNORI KAWANO, YOUICHIRO IWASHITA, IKUKO TAKASAKI, IKURO MARUYAMA, HIROYUKI ARIKAWA, KATSUICHIRO INOUE, NAOYUKI SHINOHARA, SHUNJI NAGAOKA, YOSHINOBU OHIRA
Publikováno v:
Journal of Applied Physiology; 1996, Vol. 81 Issue 1, p156-163, 8p