Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ikuko Maejima"'
Autor:
Ikuko Maejima, Taichi Hara, Satoshi Tsukamoto, Hiroyuki Koizumi, Takeshi Kawauchi, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Inoya Isobe, Kazuo Emoto, Hidetaka Kosako, Ken Sato
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract RAB35 is a multifunctional small GTPase that regulates endocytic recycling, cytoskeletal rearrangement, and cytokinesis. However, its physiological functions in mammalian development remain unclear. Here, we generated Rab35-knockout mice and
Externí odkaz:
https://doaj.org/article/89423380689a45e49cef96f897f7e01c
Autor:
Waleska Kerllen Martins, Maryana do Nascimento da Silva, Kiran Pandey, Ikuko Maejima, Ercília Ramalho, Vania Claudia Olivon, Susana Nogueira Diniz, Daniel Grasso
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100033- (2021)
Autophagy is a critical metabolic process that supports homeostasis at a basal level and is dynamically regulated in response to various physiological and pathological processes. Autophagy has some etiologic implications that support certain patholog
Externí odkaz:
https://doaj.org/article/16a96c5e91654a9ab78c2a8b5837733a
Autor:
Ikuko Maejima, Ken Sato
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 1971-1980 (2025)
In eukaryotic cells, organelles in the secretory, lysosomal, and endocytic pathways actively exchange biological materials with each other through intracellular membrane trafficking, which is the process of transporting the cargo of proteins, lipids,
Externí odkaz:
https://doaj.org/article/c87dea2c00d84d87a5f52afd5ed26e9a
Autor:
Taichi Hara, Ikuko Maejima, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Satoshi Tsukamoto, Mika Tsunoda, Aguri Ono, Shota Yamakoshi, Satoshi Oikawa, Ken Sato
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007647 (2018)
Rer1 is a retrieval receptor for endoplasmic reticulum (ER) retention of various ER membrane proteins and unassembled or immature components of membrane protein complexes. However, its physiological functions during mammalian development remain uncle
Externí odkaz:
https://doaj.org/article/cece6fc0cbb14093a60eabc14359de91
Autor:
Yoshitaka Isaka, Tomonori Kimura, Atsushi Takahashi, Yoshitsugu Takabatake, Tamotsu Yoshimori, Satoshi Minami, Ikuko Maejima, Taiji Matsusaka, Takeshi Yamamoto, Isao Matsui, Jun-ya Kaimori, Tomoko Namba, Fumio Niimura, Jun Matsuda
Publikováno v:
Diabetes. 66:1359-1372
Advanced glycation end products (AGEs) are involved in the progression of diabetic nephropathy. AGEs filtered by glomeruli or delivered from the circulation are endocytosed and degraded in the lysosomes of kidney proximal tubular epithelial cells (PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bfb6f42d40038d50e7e6336340ed84
https://doi.org/10.2337/db16-0397
https://doi.org/10.2337/db16-0397
Autor:
Daniel Grasso, Susana Nogueira Diniz, Ikuko Maejima, Kiran Pandey, Ercília da Silva Ramalho, Vania Claudia Olivon, Waleska Kerllen Martins, Maryana N. Silva
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss, Pp 100033-(2021)
Current Research in Pharmacology and Drug Discovery
Current Research in Pharmacology and Drug Discovery
Autophagy is a critical metabolic process that supports homeostasis at a basal level and is dynamically regulated in response to various physiological and pathological processes. Autophagy has some etiologic implications that support certain patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d7fed6ea7d6fa60fc24998127dae62
https://doi.org/10.1016/j.crphar.2021.100033
https://doi.org/10.1016/j.crphar.2021.100033
Autor:
Shota Yamakoshi, Ikuko Maejima, Satoshi Tsukamoto, Hisae Kobayashi, Mika Tsunoda, Ken Sato, Taichi Hara, Rika Hirai, Satoshi Oikawa, Aguri Ono, Tomoko Akuzawa
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 9, p e1007647 (2018)
PLoS Genetics, Vol 14, Iss 9, p e1007647 (2018)
Rer1 is a retrieval receptor for endoplasmic reticulum (ER) retention of various ER membrane proteins and unassembled or immature components of membrane protein complexes. However, its physiological functions during mammalian development remain uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8c71aa74790be69629b7a65969fd2d
https://pubmed.ncbi.nlm.nih.gov/30260951
https://pubmed.ncbi.nlm.nih.gov/30260951
Autor:
Naoki Kurotori, Hiroko Omori, Kanae Shirahama-Noda, Takashi Satoh, Keisuke Tabata, Ikuko Maejima, Tatsuya Saitoh, Tamotsu Yoshimori, Shizuo Akira, Kohichi Matsunaga, Takeshi Noda, Toshiaki Isobe, Tohru Ichimura
Publikováno v:
Nature Cell Biology. 11:385-396
Beclin 1, a protein essential for autophagy, binds to hVps34/Class III phosphatidylinositol-3-kinase and UVRAG. Here, we have identified two Beclin 1 associated proteins, Atg14L and Rubicon. Atg14L and UVRAG bind to Beclin 1 in a mutually exclusive m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e7c2725aaf07e43579a104657cfd33
https://doi.org/10.1038/ncb1846
https://doi.org/10.1038/ncb1846
Publikováno v:
Methods (San Diego, Calif.). 75
Autophagy is a bulk degradation system that is induced under stress conditions such as nutrient deprivation. Selective autophagy, including xenophagy and mitophagy, is believed to play important roles in the development of several diseases. Consequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d799d4b64be000b7c0bc84e6ce8287b
https://pubmed.ncbi.nlm.nih.gov/25542097
https://pubmed.ncbi.nlm.nih.gov/25542097
Publikováno v:
Scientific Reports
Rhodopsin is a pigment in photoreceptor cells. Some rhodopsin mutations cause the protein to accumulate in the endoplasmic reticulum (ER), leading to photoreceptor degeneration. Although several mutations have been reported, how mutant rhodopsin is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbe93c2424b4480385262b7b0f6c24e
https://doi.org/10.1038/srep05973
https://doi.org/10.1038/srep05973