Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Ikuko Koyama"'
Publikováno v:
PLoS Biology, Vol 22, Iss 9, p e3002777 (2024)
Organelles have unique structures and molecular compositions for their functions and have been classified accordingly. However, many organelles are heterogeneous and in the process of maturation and differentiation. Because traditional methods have a
Externí odkaz:
https://doaj.org/article/7a9a9065b06a4579bbde1df68ca0b69c
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The formation of autophagosomes involves dynamic morphological changes of a phagophore from a flat membrane cisterna into a cup-shaped intermediate and a spherical autophagosome. However, the physical mechanism behind these morphological cha
Externí odkaz:
https://doaj.org/article/c41a3c8c3e29466aa516f903c043e45e
Autor:
Saori Shinoda, Yuji Sakai, Takahide Matsui, Masaaki Uematsu, Ikuko Koyama-Honda, Jun-ichi Sakamaki, Hayashi Yamamoto, Noboru Mizushima
Publikováno v:
eLife, Vol 12 (2024)
During macroautophagy, cytoplasmic constituents are engulfed by autophagosomes. Lysosomes fuse with closed autophagosomes but not with unclosed intermediate structures. This is achieved in part by the late recruitment of the autophagosomal SNARE synt
Externí odkaz:
https://doaj.org/article/ce4db38e03334ce29e4228c492ac1adb
Publikováno v:
Cell Structure and Function, Vol 47, Iss 2, Pp 89-99 (2022)
In macroautophagy, disk-shaped double-membrane structures called phagophores elongate to form cup-shaped structures, becoming autophagosomes upon closure. These autophagosomes then fuse with lysosomes to become autolysosomes and degrade engulfed mate
Externí odkaz:
https://doaj.org/article/d21922effbf64de196871b111f7de41e
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101466- (2020)
Summary: Autophagy is an intracellular degradation process that is mediated by de novo formation of autophagosomes. Autophagosome formation involves dynamic morphological changes; a disk-shaped membrane cisterna grows, bends to become a cup-shaped st
Externí odkaz:
https://doaj.org/article/fd63adf01fb54f95b21259dca5e0e033
Autor:
Naonobu Fujita, Wilson Huang, Tzu-han Lin, Jean-Francois Groulx, Steve Jean, Jen Nguyen, Yoshihiko Kuchitsu, Ikuko Koyama-Honda, Noboru Mizushima, Mitsunori Fukuda, Amy A Kiger
Publikováno v:
eLife, Vol 6 (2017)
Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throug
Externí odkaz:
https://doaj.org/article/1cacc78f0b644c31b7ecb37658e9d198
Autor:
Ikuko Koyama-Honda, Noboru Mizushima
Publikováno v:
Autophagy
STX17 (syntaxin 17) mediates autophagosome-lysosome fusion, and the translocation of STX17 to autophagosomes is characteristic of this process. STX17 arrives at autophagosomes when they are closed, stays there for approximately 10 min to promote fusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77865cdbd2103e09bbaa3f70350aa4c4
https://doi.org/10.1080/15548627.2022.2079337
https://doi.org/10.1080/15548627.2022.2079337
Autor:
Tadayuki Komori, Tomoki Kuwahara, Tetta Fujimoto, Sakurai, Maria, Ikuko Koyama-Honda, Mitsunori Fukuda, Takeshi Iwatsubo
Publikováno v:
Journal of Cell Science; Jul2023, Vol. 136 Issue 14, p1-13, 13p
The formation of autophagosomes involves dynamic morphological changes of a phagophore from a disk-shaped membrane cisterna into a cup-shaped intermediate and a spherical autophagosome. However, the physical mechanism behind these morphological chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02d183e9a5c148e6ab6473d63ebd5ba
https://doi.org/10.1101/2022.07.20.500884
https://doi.org/10.1101/2022.07.20.500884
Autor:
Morishita, Hideaki, Eguchi, Tomoya, Tsukamoto, Satoshi, Sakamaki, Yuriko, Takahashi, Satoru, Saito, Chieko, Ikuko, Koyama-Honda, Mizushima, Noboru, Satoshi, Tsukamoto
Publikováno v:
Nature. 592:634-638
The eye lens of vertebrates is composed of fibre cells in which all membrane-bound organelles undergo degradation during terminal differentiation to form an organelle-free zone. The mechanism that underlies this large-scale organelle degradation rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::c5fa447559ef511308a3d4ceb683c283
https://repo.qst.go.jp/records/82739
https://repo.qst.go.jp/records/82739