Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Ikuko Iwamoto"'
Publikováno v:
Cells, Vol 13, Iss 6, p 540 (2024)
POGZ (Pogo transposable element derived with ZNF domain) is known to function as a regulator of gene expression. While variations in the POGZ gene have been associated with intellectual disabilities and developmental delays in humans, the exact patho
Externí odkaz:
https://doaj.org/article/7d96add757d245cb9636940aaa1e8b02
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-16 (2017)
Abstract While Munc18–1 interacts with Syntaxin1 and controls the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex to regulate presynaptic vesicle fusion in developed neurons, this molecule is like
Externí odkaz:
https://doaj.org/article/7e63edebeb7d490bb2393194cee713d5
Autor:
Yutaka Inaguma, Nanako Hamada, Hidenori Tabata, Ikuko Iwamoto, Makoto Mizuno, Yoshiaki V Nishimura, Hidenori Ito, Rika Morishita, Motomasa Suzuki, Kinji Ohno, Toshiyuki Kumagai, Koh‐ichi Nagata
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 414-429 (2014)
Abstract Marinesco‐Sjögren syndrome (MSS) is a rare autosomal recessively inherited disorder with mental retardation (MR). Recently, mutations in the SIL1 gene, encoding a co‐chaperone which regulates the chaperone HSPA5, were identified as a ma
Externí odkaz:
https://doaj.org/article/89dc98c8438741249d16fb5cf7b2968a
Publikováno v:
Journal of Neurochemistry. 165:334-347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64d30368ba5896ed94f0006aa85e7606
https://doi.org/10.1111/jnc.15783
https://doi.org/10.1111/jnc.15783
Publikováno v:
Developmental Neuroscience. 44:643-650
Polo-like kinase 4 (Plk4) is a ser/thr kinase, which plays a central role in centriole duplication during the cell cycle. PLK4 gene abnormalities are responsible for autosomal recessive chorioretinopathy-microcephaly syndrome and Seckel syndrome. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eabdca84842592699313e286c731571
https://doi.org/10.1159/000526914
https://doi.org/10.1159/000526914
Publikováno v:
Developmental Neuroscience. 44:162-170
Centrosomal protein 152 (Cep152) regulates centriole duplication as a molecular scaffold during the cell cycle. Its gene abnormalities are responsible for autosomal recessive primary microcephaly 9 and Seckel syndrome. In this study, we prepared an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f544a6aa50ba07d43e14548cdf1aa0
https://doi.org/10.1159/000523922
https://doi.org/10.1159/000523922
Publikováno v:
Developmental neuroscience.
Plk4 (polo-like kinase 4) is a Ser/Thr-kinase which plays a central role in centriole duplication during the cell cycle. PLK4 gene abnormalities are responsible for autosomal recessive chorioretinopathy-microcephaly syndrome and Seckel syndrome. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f8c8f35caf150f27efa9a2df76170cd
https://pubmed.ncbi.nlm.nih.gov/36067731
https://pubmed.ncbi.nlm.nih.gov/36067731
Publikováno v:
Journal of Neurochemistry. 157:1167-1181
Heterotrimeric G-proteins are composed of α, β, and γ subunits, and function as signal transducers. Critical roles of the α-subunits of Gi/o family heterotrimeric G-proteins, Gαi2, and Gαo1, have so far been reported in brain development and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2ad223fcaec1f074e2a4e37dbf5627
https://doi.org/10.1111/jnc.15205
https://doi.org/10.1111/jnc.15205
Autor:
Koh-ichi Nagata, Hidenori Tabata, Mariko Noda, Ikuko Iwamoto, Hidenori Ito, Takanori Yamagata
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Per3 is one of the primary components of circadian clock system. While circadian dysregulation is known to be involved in the pathogenesis of several neuropsychiatric diseases. It remains largely unknown whether they participate in embryonic brain de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92e4fd374b0f7ac7d783a7459d8ff41
http://link.springer.com/article/10.1038/s41598-019-42390-9
http://link.springer.com/article/10.1038/s41598-019-42390-9
Autor:
Hidenori Ito, Hidenori Tabata, Koh-ichi Nagata, Noriko Kawamura, Rika Morishita, Ikuko Iwamoto, Nanako Hamada, Kyoko Ibaraki
Publikováno v:
Developmental Neuroscience. 41:139-148
POGZ is a heterochromatin protein 1 α-binding protein and regulates gene expression. On the other hand, accumulating pieces of evidence indicate that the POGZ gene abnormalities are involved in various neurodevelopmental disorders. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351bc76f01af2724fb6a837e65d01c84
https://doi.org/10.1159/000502128
https://doi.org/10.1159/000502128