Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ikuhisa Yakuo"'
Autor:
Koji Ito, Ikuhisa Yakuo, Hiroyuki Funaoka, Shinobu Hayakawa, Hiroaki Hosoe, Yasuhiko Ohkaru, Makoto Nishimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 101, Iss 1, Pp 58-65 (2006)
The purpose of this study was to develop and evaluate a direct sandwich enzyme-linked immunosorbent assay (ELISA) for the immunoglobulin E (IgE) in serum and plasma from guinea pig using mouse monoclonal antibodies specific for guinea-pig IgE. Mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7616b81f5dc27f051407aca7d748e996
http://www.sciencedirect.com/science/article/pii/S1347861319344755
http://www.sciencedirect.com/science/article/pii/S1347861319344755
Publikováno v:
Pharmacology and Toxicology. 89:171-176
The present study was performed to compare the properties of ebastine--the long duration of antiallergic effect and less penetration to the CNS--with those of other H1-antihistamines. Passive cutaneous anaphylactic reaction was induced and the dye le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9913866b521793e758a2022690c87ea
https://doi.org/10.1111/j.0901-9928.2001.890405.x
https://doi.org/10.1111/j.0901-9928.2001.890405.x
Publikováno v:
Journal of Allergy and Clinical Immunology. 107:123-128
Background: Allergic rhinitis is characterized by tissue accumulation of inflammatory cells. CC chemokines, including monocyte chemotactic protein (MCP) 1, MCP-3, RANTES, and eotaxin, are thought to play an important role in inducing selective recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ba780c490a26dd20d5fb80d884261e
https://doi.org/10.1067/mai.2001.111236
https://doi.org/10.1067/mai.2001.111236
Publikováno v:
Pharmaceutical Research. 14:208-212
Purpose. The bronchodilator effect of salbutamol formulated in hydrofluoroalkane-134a (HFA-134a), a Chlorofluorocarbon (CFC)-free propellant for metered dose inhalation (MDI) devices, was compared with that of salbutamol formulated in CFC in anesthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1e892015d9d6a0a7ac3b99e2ca6575e
https://doi.org/10.1023/a:1012056928780
https://doi.org/10.1023/a:1012056928780
Publikováno v:
Japanese Journal of Pharmacology. 67:263-266
To clarify the antiallergic effect and antiallergic mechanism of AL-3264 (N-[4-[4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(6-methyl-3-pyridyl)acrylamide) in monkeys, its effects on the Prausnitz-Kustner (P-K) reaction, the histamine skin reaction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bab774302d19c5c35dc60d2d7afe973
https://doi.org/10.1254/jjp.67.263
https://doi.org/10.1254/jjp.67.263
Autor:
Katsumi Ishii, Ikuhisa Yakuo, Kunihiko Takeyama, Tadahiko Karasawa, Hideo Nakamura, Yasuhiro Seto, Kiyomi Imano
Publikováno v:
Folia Pharmacologica Japonica. 103:121-135
The anti-allergic activity of ebastine, a novel antihistamine, was assessed in comparison with several antihistamines. 1) Orally administered ebastine dose-dependently inhibited 7-day homologous passive cutaneous anaphylaxis (PCA), experimental aller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b502be067c74f5027125dbebf5b1f19d
https://doi.org/10.1254/fpj.103.121
https://doi.org/10.1254/fpj.103.121
Autor:
Ikuhisa Yakuo, Kiyomi Imano, Hideo Nakamura, Katsuya Seguro, Atsuko Kita, Yasuo Ariyoshi, Noriki Nio
Publikováno v:
FEBS Letters. 319:225-228
To delineate the binding site in the human immunoglobulin E (IgE) molecule to the Fc epsilon receptor on basophils and mast cells, we chemically synthesized a total of 71 peptide fragments within the sequence Ser300-Lys547 in the human IgE molecule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a652bd1d67a3e3fd1950e8192ba69bd0
https://doi.org/10.1016/0014-5793(93)80551-5
https://doi.org/10.1016/0014-5793(93)80551-5
Autor:
Kenji Kawada, Akihide Koda, Takashi Nose, Hiroichi Nagai, Akitsugu Ojima, Ikuhisa Yakuo, Hiroaki Yamada, Kaito Tsurumi
Publikováno v:
Ensho. 10:471-476
A glomerulonephritis was induced in mice by injection of subnephrotoxic dose of nephrotoxic serum (NTS) after preimmunization with rabbit IgG. In order to characterize this glomerulonephritis, light, electron and immunofluorescence microscopic studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd6fd666be8c7b809041580e6996867
https://doi.org/10.2492/jsir1981.10.471
https://doi.org/10.2492/jsir1981.10.471
Publikováno v:
Japanese journal of pharmacology. 65(1)
The effects of AL-3264, which exhibits a 5-lipoxygenase (5-LO) inhibiting property by blocking histamine H1-receptors and inhibition of histamine release, were examined on leukotriene (LT) production and LT-mediated responses. AL-3264 (1-30 microM) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f3980ece4d09968795b7a56fb78d02
https://pubmed.ncbi.nlm.nih.gov/7916384
https://pubmed.ncbi.nlm.nih.gov/7916384
Publikováno v:
Japanese Journal of Pharmacology. 73:99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5113296859f6d6c5cd3eea89a667592f
https://doi.org/10.1016/s0021-5198(19)44902-0
https://doi.org/10.1016/s0021-5198(19)44902-0