Kinetic and structural characterization of therapeutic albumin chemical functionalization using complementary mass spectrometry techniques

Autor: Daniel Scherman, Yannis-Nicolas François, Gilles Clodic, Pascal Houzé, Rabah Gahoual, Nathalie Mignet, Gérard Bolbach, Ikram Ould-Melha

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2020, 185, pp.113242. ⟨10.1016/j.jpba.2020.113242⟩

International audience; Protein conjugates such as antibody-drugs conjugates (ADCs) represents the next generation of therapeutic proteins. They allow to combine the biological properties of the protein format with the characteristics of the conjugat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0272ec9e4e578e48cbc3db5a88959884
https://hal.archives-ouvertes.fr/hal-03022806/document