Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ikram Mezghani"'
Autor:
Zhuqing Li, Brandon Sumpio, Enya Wang, Mauricio Contreras, Ikram Mezghani, Georgios Theocharidis, Aristidis Veves
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102029- (2023)
Summary: Here, we present a protocol for the integration of human skin onto the backs of diabetic immunodeficient mice, providing a versatile in vivo model for mimicking and studying mechanisms involved in impaired cutaneous wound healing. This proto
Externí odkaz:
https://doaj.org/article/39d9b3dd8ac34b16bfd1fc12f739c511
Autor:
Georgios Theocharidis, Beena E. Thomas, Debasree Sarkar, Hope L. Mumme, William J. R. Pilcher, Bhakti Dwivedi, Teresa Sandoval-Schaefer, Ruxandra F. Sîrbulescu, Antonios Kafanas, Ikram Mezghani, Peng Wang, Antonio Lobao, Ioannis S. Vlachos, Biraja Dash, Henry C. Hsia, Valerie Horsley, Swati S. Bhasin, Aristidis Veves, Manoj Bhasin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Diabetic foot ulcers (DFUs) remain a complication of diabetes that are difficult to heal and lead to disability. Here the authors use single-cell RNA-sequencing and spatial transcriptomics to characterize the DFU cellular landscape and identify a pop
Externí odkaz:
https://doaj.org/article/f9eeb6aeee15457486ee4ea3a39b9697
Autor:
Brandon J Sumpio, Ikram Mezghani, Enya Wang, Zhuqing Li, Eleftheria-Angeliki Valsami, Georgios Theocharidis, Aristidis Veves
Publikováno v:
Expert Opinion on Investigational Drugs. 32:95-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9762403fc3cf80dd50f2b47ceb61175d
https://doi.org/10.1080/13543784.2023.2178418
https://doi.org/10.1080/13543784.2023.2178418
Autor:
Georgios Theocharidis, Hyunwoo Yuk, Heejung Roh, Liu Wang, Ikram Mezghani, Jingjing Wu, Antonios Kafanas, Mauricio Contreras, Brandon Sumpio, Zhuqing Li, Enya Wang, Lihong Chen, Chuan Fei Guo, Navin Jayaswal, Xanthi-Leda Katopodi, Nikolaos Kalavros, Christoph S. Nabzdyk, Ioannis S. Vlachos, Aristidis Veves, Xuanhe Zhao
Publikováno v:
Nature Biomedical Engineering. 6:1118-1133
Diabetic foot ulcers and other chronic wounds with impaired healing can be treated with bioengineered skin or with growth factors. However, most patients do not benefit from these treatments. Here we report the development and preclinical therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd35643422d86dfcf71c170ae03c017
https://doi.org/10.1038/s41551-022-00905-2
https://doi.org/10.1038/s41551-022-00905-2
Autor:
Brandon J. Sumpio, Zhuqing Li, Enya Wang, Ikram Mezghani, Georgios Theocharidis, Aristidis Veves
Publikováno v:
Advances in therapy.
Diabetic foot ulcers are a health crisis that affect millions of individuals worldwide. Current standard of care involves diligent wound care with adjunctive antibiotics and surgical debridement. However, despite this, the majority will still become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc309eca19ca199140690e440b4ee780
https://pubmed.ncbi.nlm.nih.gov/36264535
https://pubmed.ncbi.nlm.nih.gov/36264535
Autor:
Aristidis Veves, Ikram Mezghani, Jie Dong, Lihong Chen, Navin Jayaswal, Weijie Zhang, Ying Zhang
Publikováno v:
Advances in Therapy
Mast cells (MCs) are granulated, immune cells of the myeloid lineage that are present in connective tissues. Apart from their classical role in allergies, MCs also mediate various inflammatory responses due to the nature of their secretory products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f410073f7053d4a6dbee800ee84b79e
https://doi.org/10.1007/s12325-020-01499-4
https://doi.org/10.1007/s12325-020-01499-4
Autor:
Biraja C. Dash, Ioannis S. Vlachos, Ruxandra F. Sîrbulescu, Henry C. Hsia, Beena E Thomas, Ikram Mezghani, Teresa Sandoval-Schaefer, Bhakti Dwivedi, Georgios Theocharidis, Manoj Bhasin, Peng Wang, Aristidis Veves, Debasree Sarkar, Antonio Lobao, Valerie Horsley, Swati S Bhasin, William Jr Pilcher, Antonios Kafanas
To understand the diabetic wound healing microenvironment, we profiled 174,962 single cells from foot, forearm, and PBMCs using single-cell RNA sequencing (scRNASeq) approach. Our analysis shows enrichment of a unique population of fibroblasts overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3815fa13e83552c4561976db0eea455a
https://doi.org/10.1101/2021.03.11.434413
https://doi.org/10.1101/2021.03.11.434413
Autor:
Shade Rodriguez, James E. Kirby, Ikram Mezghani, Kenneth P. Smith, Sarah DuBois-Coyne, Amber Chopelas, Annie Cheng, Mustafa Talay
Publikováno v:
Journal of Clinical Microbiology
The COVID-19 pandemic has severely disrupted worldwide supplies of viral transport media (VTM) due to widespread demand for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-PCR (RT-PCR) testing. In response to this o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f67172cc0e1ff03b809ad0c01e6d03
https://pubmed.ncbi.nlm.nih.gov/32404481
https://pubmed.ncbi.nlm.nih.gov/32404481