Výsledky vyhledávání - "Ikki Kawakatsu"

Akademický článek

2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice.

Autor: Hirofumi Morihara, Masanori Obana, Shota Tanaka, Ikki Kawakatsu, Daisuke Tsuchiyama, Shota Mori, Hiroshi Suizu, Akiko Ishida, Rumi Kimura, Izuru Tsuchimochi, Makiko Maeda, Takehiko Yoshimitsu, Yasushi Fujio, Hiroyuki Nakayama

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189948 (2017)

Excessive levels of reactive oxygen species (ROS) and impaired Ca2+ homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several organs, treatment with 2-

Externí odkaz: https://doaj.org/article/7621d1ec32c54fc198e89394bb5cc0dd

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2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice

Autor: Izuru Tsuchimochi, Masanori Obana, Makiko Maeda, Rumi Kimura, Takehiko Yoshimitsu, Hiroshi Suizu, Shota Mori, Hiroyuki Nakayama, Daisuke Tsuchiyama, Ikki Kawakatsu, Hirofumi Morihara, Yasushi Fujio, Shota Tanaka, Akiko Ishida

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189948 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2356102ecd25a0c83396909e55d67f25
https://pubmed.ncbi.nlm.nih.gov/29267336

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Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice

Autor: Daisuke Tsuchiyama, Ikki Kawakatsu, Makiko Maeda, Kota Tonegawa, Masanori Obana, Satoshi Obika, Hiroyuki Nakayama, Hirofumi Morihara, Yasushi Fujio, Tomomi Mohri, Harunori Oiwa, Tsuyoshi Yamamoto

Publikováno v: Journal of cardiovascular pharmacology and therapeutics. 22(3)

Background: Phospholamban (PLN) inhibition enhances calcium cycling and is a potential novel therapy for heart failure (HF). Antisense oligonucleotides (ASOs) are a promising tool for unmet medical needs. Nonviral vector use of locked nucleic acid (L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ec356518ebe0e66f1dcdacd5f8bd04
https://pubmed.ncbi.nlm.nih.gov/27811197

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