Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ikhlas S.A. Ahmed"'
Publikováno v:
Journal of Biological Chemistry. 285:24775-24782
Tumorigenesis requires the concerted action of multiple pathways, including pathways that stimulate proliferation and metabolism. Epidermal growth factor receptor (EGFR) is a transmembrane receptor-tyrosine kinase that is associated with cancer progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b839b16d563ab766662ffeaa9c774590
https://doi.org/10.1074/jbc.m110.134585
https://doi.org/10.1074/jbc.m110.134585
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 333:564-573
Tumorigenesis requires the concerted action of multiple pathways, including pathways that stimulate proliferation and increase metabolism. Progesterone receptor membrane component 1 (Pgrmc1) is related to cytochrome b5, binds to heme, and is associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a87795dac25999734787ba7716c5cf8
https://doi.org/10.1124/jpet.109.164210
https://doi.org/10.1124/jpet.109.164210
Publikováno v:
Pharmacology & Therapeutics. 121:14-19
Hormone signaling is important in a number of disease states, and hormone receptors are effective therapeutic targets. PGRMC1 (progesterone receptor membrane component 1) is a member of a multi-protein complex that binds to progesterone and other ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c9d0e4725cb94306a66f0ff71abdfe
https://doi.org/10.1016/j.pharmthera.2008.09.006
https://doi.org/10.1016/j.pharmthera.2008.09.006
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1772:1103-1111
Cancer chemotherapy inhibits tumor growth, in part, by triggering apoptosis, and anti-apoptotic proteins reduce the effectiveness of chemotherapy. Clusterin, a chaperone-like protein that binds to apoptotic and DNA repair proteins, is induced by chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7705f582e737cccc7e69e91af4743e
https://doi.org/10.1016/j.bbadis.2007.06.004
https://doi.org/10.1016/j.bbadis.2007.06.004
Publikováno v:
International journal of cancer. 131(2)
Cancer is one of the leading causes of death, and there is an urgent need for new biomarkers and therapeutic targets. The progesterone receptor membrane component 1 (Pgrmc1) protein is upregulated in multiple types of cancer, and Pgrmc1 is required f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450abbc09907ffd6d24a9373194efb5
https://pubmed.ncbi.nlm.nih.gov/21918976
https://pubmed.ncbi.nlm.nih.gov/21918976