Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ikhlaaq Ahmed"'
Autor:
Dennis C. Sgroi, Kai Treuner, Yi Zhang, Tammy Piper, Ranelle Salunga, Ikhlaaq Ahmed, Lucy Doos, Sarah Thornber, Karen J. Taylor, Elena Brachtel, Sarah Pirrie, Catherine A. Schnabel, Daniel Rea, John M. S. Bartlett
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background Multiple clinical trials demonstrate consistent but modest benefit of adjuvant extended endocrine therapy (EET) in HR + breast cancer patients. Predictive biomarkers to identify patients that benefit from EET are critical to balan
Externí odkaz:
https://doaj.org/article/f73219a1ffd7495699a8f9ef0b2330f6
Autor:
Lynn Quek, Paul Ferguson, Marlen Metzner, Ikhlaaq Ahmed, Alison Kennedy, Catherine Garnett, Sally Jeffries, Claudia Walter, Kim Piechocki, Adele Timbs, Robert Danby, Manoj Raghavan, Andrew Peniket, Mike Griffiths, Andrew Bacon, Janice Ward, Keith Wheatley, Paresh Vyas, Charles Craddock
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 193-204 (2016)
Abstract: Disease relapse is the major cause of treatment failure after allogeneic stem cell transplantation (allo-SCT) in acute myeloid leukemia (AML). To identify AML-associated genes prognostic of AML relapse post–allo-SCT, we resequenced 35 gen
Externí odkaz:
https://doaj.org/article/c7aa4ecc15494ffc87dd288a52539336
Autor:
Daniel W. Rea, Catherine A. Schnabel, Sarah J. Pirrie, Elena F. Brachtel, Karen J. Taylor, Sarah Thornber, Lucy Doos, Ikhlaaq Ahmed, Ranelle C. Salunga, Tammy Piper, Yi Zhang, Kai Treuner, Dennis C. Sgroi, John M.S. Bartlett
Purpose:The Breast Cancer Index (BCI) HOXB13/IL17BR (H/I) ratio predicts benefit from extended endocrine therapy in hormone receptor–positive (HR+) early-stage breast cancer. Here, we report the final analysis of the Trans-aTTom study examining BCI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f36da423f3794918ed8022d0689f3d
https://doi.org/10.1158/1078-0432.c.6532682.v1
https://doi.org/10.1158/1078-0432.c.6532682.v1
Autor:
Daniel W. Rea, Catherine A. Schnabel, Sarah J. Pirrie, Elena F. Brachtel, Karen J. Taylor, Sarah Thornber, Lucy Doos, Ikhlaaq Ahmed, Ranelle C. Salunga, Tammy Piper, Yi Zhang, Kai Treuner, Dennis C. Sgroi, John M.S. Bartlett
Supplementary Figure from Breast Cancer Index Is a Predictive Biomarker of Treatment Benefit and Outcome from Extended Tamoxifen Therapy: Final Analysis of the Trans-aTTom Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db319216c5c940dc3b3297155ab0e93
https://doi.org/10.1158/1078-0432.22488242.v1
https://doi.org/10.1158/1078-0432.22488242.v1
Autor:
Ikhlaaq Ahmed, Andrea Hodgkinson, Rebecca Bishop, Ram Malladi, Jane Nunnick, Shamyla Siddique, Aimee Jackson, Fiona L Dignan, Mohamed Elhaneid, Graham McIlroy, Paul Moss, Charles Craddock, Rachel Protheroe
Publikováno v:
Bone Marrow Transplantation. 56:2948-2955
Chronic graft-versus-host disease (cGvHD) is a major cause of non-relapse morbidity and mortality following allogeneic stem cell transplant. Over half of patients with moderate or severe cGvHD fail to respond adequately to first-line treatment with s
Autor:
Zeeshaan-Ul Hasan, Ikhlaaq Ahmed, Rubeta N. Matin, Victoria Homer, John T. Lear, Ferina Ismail, Tristan Whitmarsh, Adele C. Green, Jason Thomson, Alan Milligan, Sarah Hogan, Vanessa Van-de-Velde, Liza Mitchell-Worsford, Jonathan Kentley, Claire Gaunt, Yolande Jefferson-Hulme, Sarah J. Bowden, Piers Gaunt, Keith Wheatley, Charlotte M. Proby, Catherine A. Harwood
Background The risk of cutaneous squamous cell carcinoma (cSCC) is significantly increased in organ transplant recipients (OTRs). Clearance of actinic keratoses (AKs) is generally regarded as a surrogate biomarker for cSCC prevention. OTR-cSCC chemop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fc8457bf111b747e1d049988a541c3
https://www.repository.cam.ac.uk/handle/1810/338072
https://www.repository.cam.ac.uk/handle/1810/338072
Autor:
Elena F. Brachtel, Tammy Piper, Catherine A. Schnabel, Daniel Rea, Lucy Doos, Yi Zhang, Dennis C. Sgroi, John M. S. Bartlett, Sarah Thornber, Ikhlaaq Ahmed, Ranelle C. Salunga, Kai Treuner, Sarah Pirrie, Karen J Taylor
Publikováno v:
Cancer Research. 81:GS4-09
Background: Several biomarkers such as estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR) and Ki67 have been implicated in the pathogenesis and/or as prognostic biomarkers of breast cancer, and are utilized to determine treatm
Publikováno v:
European Journal of Trauma and Emergency Surgery. 48:647-657
Purpose Spinal collars were introduced in 1967 into the management of spinal trauma care as it was thought that this technique of immobilisation would prevent any further neurological or spinal damage in high-risk patients. The aim of this systematic
Autor:
John M.S. Bartlett, Dennis C. Sgroi, Kai Treuner, Yi Zhang, Tammy Piper, Ranelle C. Salunga, Ikhlaaq Ahmed, Lucy Doos, Sarah Thornber, Karen J. Taylor, Elena F. Brachtel, Sarah J. Pirrie, Catherine A. Schnabel, Daniel W. Rea
Publikováno v:
Bartlett, J, C. Sgroi, D, Treuner, K, Zhang, Y, Piper, T, C. Salunga, R, Ahmed, I, Doos, L, Thornber, S, Taylor, K, F. Brachtel, E, J. Pirrie, S, A Schnabel, C & Rea, D 2022, ' Breast Cancer Index is a predictive biomarker of treatment benefit and outcome from extended tamoxifen therapy: final analysis of the Trans-aTTom study ', Clinical Cancer Research, vol. 28, no. 9, pp. 1871-1880 . https://doi.org/10.1158/1078-0432.CCR-21-3385
Purpose: The Breast Cancer Index (BCI) HOXB13/IL17BR (H/I) ratio predicts benefit from extended endocrine therapy in hormone receptor–positive (HR+) early-stage breast cancer. Here, we report the final analysis of the Trans-aTTom study examining BC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beeebdce89ba3bf26abea30c1f9894e6
https://www.pure.ed.ac.uk/ws/files/278874561/1871.pdf
https://www.pure.ed.ac.uk/ws/files/278874561/1871.pdf
Autor:
John Bartlett, Yi Zhang, Dennis Sgori, Sarah Thornber, Ikhlaaq Ahmed, Catherine A. Schnabel, Tammy Piper, Elena F. Brachtel, Lucy Doos, Sarah Pirrie, Daniel Rea, Ranelle Shalunga, Kai Treuner
Publikováno v:
Cancer Research. 80:P2-11
Background: Optimizing the duration of adjuvant endocrine therapy in patients diagnosed with early stage hormone receptor-positive (HR+) breast cancer requires improved approaches to individualize disease profile and to reduce any unnecessary treatme