Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ikenna Nweze"'
Publikováno v:
The American surgeon. 83(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c292d378031b8a9867b9b87f51a320
https://pubmed.ncbi.nlm.nih.gov/28541846
https://pubmed.ncbi.nlm.nih.gov/28541846
Publikováno v:
Journal of Cellular Biochemistry. 116:133-141
Excessive nitric oxide from the inducible nitric oxide synthase (iNOS) increases shock-induced hepatic injury, hepatic dysfunction, inflammation, and mortality in animal models. Cytokines increase the expression of iNOS in hepatocytes, but the signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bcac04f5e64fd009121707d8329787
https://doi.org/10.1002/jcb.24951
https://doi.org/10.1002/jcb.24951
Publikováno v:
Shock. 39:70-76
Adenosine 3',5'-cyclic adenosine monophosphate (cAMP) activates intracellular signaling by regulating protein kinase A, calcium influx, and cAMP-binging guanine nucleotide exchange factors (Epac [exchange protein directly activated by cAMP] or cAMP-G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb72aebabac58170a56950ee572dfc86
https://doi.org/10.1097/shk.0b013e3182760530
https://doi.org/10.1097/shk.0b013e3182760530
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G116-G122
Hepatocyte inducible nitric oxide synthese (iNOS) expression is a tightly controlled pathway that mediates hepatic inflammation and hepatocyte injury in a variety of disease states. We have shown that cyclic adenosine monophosphate (cAMP) regulates c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2590266a2ab5a32dc774cb7e1a6764
https://doi.org/10.1152/ajpgi.00114.2011
https://doi.org/10.1152/ajpgi.00114.2011
Autor:
Baochun Zhang, Jaganathan Lakshmanan, Jason W. Smith, Brian G. Harbrecht, Ikenna Nweze, Carolyn M. Klinge
OBJECTIVE: Nitric oxide (NO) regulation during shock and sepsis is complex. NO production by endothelial NO synthase maintains microvascular perfusion and prevents shock-induced organ injury. However, the overproduction of NO by inducible NO synthase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae1e93ce29d96115050a6495f51350d
https://europepmc.org/articles/PMC3422572/
https://europepmc.org/articles/PMC3422572/
