Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ikenna, Obi"'
Autor:
Marco Deiana, José María Andrés Castán, Pierre Josse, Abraha Kahsay, Darío Puchán Sánchez, Korentin Morice, Natacha Gillet, Ranjitha Ravindranath, Ankit Kumar Patel, Pallabi Sengupta, Ikenna Obi, Eva Rodriguez-Marquez, Lhoussain Khrouz, Elise Dumont, Laura Abad Galán, Magali Allain, Bright Walker, Hyun Seo Ahn, Olivier Maury, Philippe Blanchard, Tangui Le Bahers, Daniel Öhlund, Jonas von Hofsten, Cyrille Monnereau, Clément Cabanetos, Nasim Sabouri
Publikováno v:
Nucleic Acids Research.
Photodynamic therapy (PDT) ideally relies on the administration, selective accumulation and photoactivation of a photosensitizer (PS) into diseased tissues. In this context, we report a new heavy-atom-free fluorescent G-quadruplex (G4) DNA-binding PS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::469e0645fdb46d166cbcbe3f405fdf5d
https://doi.org/10.1093/nar/gkad365
https://doi.org/10.1093/nar/gkad365
Autor:
Sujinna Lekmeechai, Yu-Ching Su, Marta Brant, Maria Alvarado-Kristensson, Anna Vallström, Ikenna Obi, Anna Arnqvist, Kristian Riesbeck
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Outer membrane vesicles (OMVs) play an important role in the persistence of Helicobacter pylori infection. Helicobacter OMVs carry a plethora of virulence factors, including catalase (KatA), an antioxidant enzyme that counteracts the host respiratory
Externí odkaz:
https://doaj.org/article/6da247d1e5684967898d1200e042fe42
Autor:
Adewale Philip Adedokun, Olanike Adeoye, Esta Eleluwor, Martins Oluwatobi Oke, Christopher Ibiyomi, Odira Okenwa, Obisike N. Ubendu, Ikenna Obi
Publikováno v:
Day 3 Wed, August 03, 2022.
Following multi-disciplinary reviews, an opportunity was identified to restore production and unlock incremental reserves from well X, a dual completion in two different reservoirs but subsequently deserted due to long term community crisis that led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80906294c683cb9faebee8a59f9768cd
https://doi.org/10.2118/212039-ms
https://doi.org/10.2118/212039-ms
Autor:
Jan Jamroskovic, Erik Chorell, Matilda Rentoft, Vandana Singh, Nasim Sabouri, Karam Chand, Fredrik Westerlund, Ikenna Obi
Publikováno v:
Nucleic Acids Research
G-quadruplex (G4) structures are stable non-canonical DNA structures that are implicated in the regulation of many cellular pathways. We show here that the G4-stabilizing compound PhenDC3 causes growth defects in Schizosaccharomyces pombe cells, espe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e57ca5e09a0e52ef5403d25fa699a9
https://doi.org/10.1093/nar/gkaa820
https://doi.org/10.1093/nar/gkaa820
Publikováno v:
Angewandte Chemie International Edition. 59:896-902
The design of turn-on dyes with optical signals sensitive to the formation of supramolecular structures provides fascinating and underexplored opportunities for G-quadruplex (G4) DNA detection and characterization. Here, we show a new switching mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d66ac9c26b8bf754d663a59a9af8bc1
https://doi.org/10.1002/anie.201912027
https://doi.org/10.1002/anie.201912027
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Bacteria shed a diverse set of outer membrane vesicles that function as transport vehicles to deliver effector molecules and virulence factors to host cells. Helicobacter pylori is a gastric pathogen that infects half of the world’s popula
Externí odkaz:
https://doaj.org/article/b9c36a95c380484082d3856a3eb8d374
Publikováno v:
Nucleic Acids Research
The identification of G-quadruplex (G4) binding proteins and insights into their mechanism of action are important for understanding the regulatory functions of G4 structures. Here, we performed an unbiased affinity-purification assay coupled with ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535e2ab3ca941ee79908e6e6604da96f
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187116
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187116
Autor:
Ikenna Obi, Marco Deiana, Nasim Sabouri, Måns Andreasson, Shanmugam Tamilselvi, Karam Chand, Erik Chorell
Publikováno v:
ACS Chemical Biology
G-quadruplex (G4) DNA structures are widespread in the human genome and are implicated in biologically important processes such as telomere maintenance, gene regulation, and DNA replication. Guanine-rich sequences with potential to form G4 structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87952d16abb1b3d3ea1af28ef11169fd
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187118
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187118
Publikováno v:
Chemical communications (Cambridge, England). 56(91)
Phen-DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d08723e6a5d0a9a2954f984d0281675
https://pubmed.ncbi.nlm.nih.gov/33118567
https://pubmed.ncbi.nlm.nih.gov/33118567
Autor:
Rajendra Kumar, Kazutoshi Kasho, Ikenna Obi, Kristoffer Brännström, Rabindra Nath Das, Parham L. Pourbozorgi, James E. Mason, Jan Jamroskovic, Nasim Sabouri, Mattias Hedenström, Mara Doimo, Sjoerd Wanrooij, Sebastian Sulis Sato, Marco Deiana, Erik Chorell, Almaz Akhunzianov, Paolo Medini, Daniel Öhlund, Karam Chand
Publikováno v:
Journal of the American Chemical Society
The signal transducer and activator of transcription 3 (STAT3) protein is a master regulator of most key hallmarks and enablers of cancer, including cell proliferation and the response to DNA damage. G-Quadruplex (G4) structures are four-stranded non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65413fad2479ca1592337e387af21cd
https://pubmed.ncbi.nlm.nih.gov/31990532
https://pubmed.ncbi.nlm.nih.gov/31990532