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Autor:
John C. Burnett, Alessandro Cataliotti, Francesco Pitrolo, Fletcher A. Miller, Diego Bellavia, Patricia A. Pellikka, Elise A. Oehler, Ikeda Iasuhiro, Jason M. Tonne, Margaret M. Redfield
Publikováno v:
Journal of Cardiac Failure. 16:S72
G-protein coupled receptors (GPCRs), in addition to signaling through heterotrimeric G proteins, also signal through b-arrestins. GPCR ‘‘biased ligands’’ preferentially engage a subset of receptor signals, for example activating either G-prot