Výsledky vyhledávání - "Ikechukwu B. Jacob"

Akademický článek

Human surfactant protein A inhibits SARS-CoV-2 infectivity and alleviates lung injury in a mouse infection model

Autor: Ikechukwu B. Jacob, Amanda Gemmiti, Weichuan Xiong, Erin Reynolds, Brian Nicholas, Saravanan Thangamani, Hongpeng Jia, Guirong Wang

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionSARS coronavirus 2 (SARS-CoV-2) infects human angiotensin-converting enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S protein is highly glycosylated and could be a target for lectins. Surfactant prote

Externí odkaz: https://doaj.org/article/64a2bb928cd844d0ac49d07dda507a5c

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Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial Cells

Autor: Ikechukwu B Jacob, Amanda Gemmiti, Weichuan Xiong, Erin Reynolds, Brian Nicholas, Saravanan Thangamani, Hongpeng Jia, Guirong Wang

Publikováno v: bioRxiv

SARS coronavirus 2 (SARS-CoV-2) infects human angiotensin-converting enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S protein is highly glycosylated and could be a target for lectins. Surfactant protein A (SP-A)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9439f13bbe2328fde1a701be7335f8
https://europepmc.org/articles/PMC10103969/

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The Enhancer-Binding Protein MifR, an Essential Regulator of α-Ketoglutarate Transport, Is Required for Full Virulence of Pseudomonas aeruginosa PAO1 in a Mouse Model of Pneumonia

Autor: Weichuan Xiong, Alexander Perna, Ikechukwu B. Jacob, Benjamin R. Lundgren, Guirong Wang

Publikováno v: Infect Immun

The opportunistic human pathogen Pseudomonas aeruginosa PAO1 has an extensive metabolism, enabling it to utilize a wide range of structurally diverse compounds to meet its nutritional and energy needs. Interestingly, the utilization of some of the mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3550a1890872c910671032b31e534d48
https://europepmc.org/articles/PMC9584295/

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