Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ik-Bum Kim"'
Array-Based Sensing of Normal, Cancerous, and Metastatic Cells Using Conjugated Fluorescent Polymers
Autor:
Oscar R. Miranda, Avinash Bajaj, Uhf Bunz, Ronnie L. Phillips, Vincent M. Rotello, DJ Jerry, Ik-Bum Kim
Publikováno v:
Journal of the American Chemical Society. 132:1018-1022
A family of conjugated fluorescent polymers was used to create an array for cell sensing. Fluorescent conjugated polymers with pendant charged residues provided multivalent interactions with cell membranes, allowing the detection of subtle difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d857baa8feae891edd1cc09470b609
https://doi.org/10.1021/ja9061272
https://doi.org/10.1021/ja9061272
Autor:
Uwe H. F. Bunz, Ik-Bum Kim, D. Joseph Jerry, Vincent M. Rotello, Avinash Bajaj, Oscar R. Miranda, Ronnie L. Phillips
Publikováno v:
Proceedings of the National Academy of Sciences. 106:10912-10916
Rapid and effective differentiation between normal and cancer cells is an important challenge for the diagnosis and treatment of tumors. Here, we describe an array-based system for identification of normal and cancer cells based on a “chemical nose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b479ac4d6fea199545ad5396a974bcc
https://doi.org/10.1073/pnas.0900975106
https://doi.org/10.1073/pnas.0900975106
Autor:
Man H. Han, Ronnie L. Phillips, Ik-Bum Kim, Uwe H. F. Bunz, Bappaditya Samanta, Z. John Zhang, Vincent M. Rotello
Publikováno v:
Chemistry - A European Journal. 15:449-456
We describe a pyrophosphate (PPi) probe that is based on a fluorescent dicarboxylate-substituted poly(para-phenyleneethynylene) (PPE) and 10 nm cobalt-iron spinel nanoparticles (NPs) in aqueous media. The spinel NPs efficiently quench the fluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbca8123df5664380f96a11512fcc89b
https://doi.org/10.1002/chem.200801403
https://doi.org/10.1002/chem.200801403
Autor:
Yu Bai, Ronnie L. Phillips, Bradley E. Carson, Todd L. Lowary, Laren M. Tolbert, Ik-Bum Kim, Uwe H. F. Bunz, Björn Tidbeck
Publikováno v:
Macromolecules. 41:7316-7320
The synthesis of two novel, water-soluble, sugar-substituted poly(p-phenyleneethynylene)s and their interactions with concanavalin A (Con A) and bacteria (Escherichia coli) are reported, and the issue of sensitivity enhancement is investigated. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7a1aa233d390720161b217194e57c9
https://doi.org/10.1021/ma8016025
https://doi.org/10.1021/ma8016025
Publikováno v:
Macromolecules. 40:5290-5293
The synthesis of two new water-soluble, carboxylate-substituted poly(p-phenyleneethynylene)s (PPE) is reported. These PPEs differ in their concentration of free carboxylate groups per repeat (two aryleneethynylenes) unit. The photophysical properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5af110f85bf80e82a41c924b2ccd779
https://doi.org/10.1021/ma070795v
https://doi.org/10.1021/ma070795v
Autor:
Partha S. Ghosh, Belma Erdogan, Chang-Cheng You, Oscar R. Miranda, Vincent M. Rotello, Ik-Bum Kim, Basar Gider, Uwe H. F. Bunz, Sai Archana Krovi
Publikováno v:
Nature Nanotechnology. 2:318-323
A sensor array containing six non-covalent gold nanoparticle-fluorescent polymer conjugates has been created to detect, identify and quantify protein targets. The polymer fluorescence is quenched by gold nanoparticles; the presence of proteins disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2377e85f887b0b70c52ba9471c523d1
https://doi.org/10.1038/nnano.2007.99
https://doi.org/10.1038/nnano.2007.99
Publikováno v:
Bioconjugate Chemistry. 18:815-820
We have demonstrated synthesis and application of a water-soluble, folate-substituted poly(p-phenyleneethynylene) (PPE) as a fluorescent contrast agent to image cancer cells. This fluorescent polymer targets and images KB cancer cells in vitro with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ca06d1bb759fc270ce2bb777ab59b
https://doi.org/10.1021/bc0603440
https://doi.org/10.1021/bc0603440
Publikováno v:
Macromolecules. 40:814-817
A water-soluble biotinylated poly(p-phenyleneethynylene) (PPE, 3) was synthesized by postfunctionalization of an amine−PPE precursor 2a and investigated for sensory responses in aqueous buffer at physiological pH. Polymer 3 shows similar sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9fd079ccc54a7c636d624b7a71cf3ba
https://doi.org/10.1021/ma061588i
https://doi.org/10.1021/ma061588i
Publikováno v:
Journal of Macromolecular Science, Part A. 41:1411-1424
2,3‐Dicyano‐5,7‐dimethyl‐6H‐1,4‐diazepine (1) is polymerized to a conjugated structure in solution by both alkaline sugar reagents and butoxide in n‐butanol and in the solid state by thermal annealing. From both infrared and nuclear mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc575309773f971949f825b7f366564
https://doi.org/10.1081/ma-200035346
https://doi.org/10.1081/ma-200035346
Autor:
Daniel J. Sandman, Jeffrey M. Njus, Ashok L. Cholli, Sangrama K. Sahoo, Dong-Chan Lee, Ik-Bum Kim
Publikováno v:
Macromolecular Symposia. 192:99-114
Topochemical solid state polymerization is a method of obtaining fully crystalline macromolecules. Herein, approaches to conjugated polymers via new solid state polymerizations and the properties of materials, especially polydiacetylenes(PDA), obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844603bdd058e045a34128a3ba38e169
https://doi.org/10.1002/masy.200390043
https://doi.org/10.1002/masy.200390043