Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ik Jae Moon"'
Autor:
Shobha Regmi, Shiva Pathak, Tung Pham Thanh, Tiep Tien Nguyen, Jong-Hyuk Sung, Simmyung Yook, Jong Oh. Kim, Chul Soon Yong, Inho Choi, Kyoung-Oh Doh, Pil-Hoon Park, Jun-Beom Park, Yoojin Seo, Bieong-Kil Kim, Dong-Mok Lee, Ik-Jae Moon, Hyung-Sik Kim, Jee-Heon Jeong
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Systemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20–50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a p
Externí odkaz:
https://doaj.org/article/7f2d9c25befd4154adca588c99ed3e06
Autor:
Pil-Hoon Park, Chul Soon Yong, Jong-Hyuk Sung, Tung Pham Thanh, Tiep Tien Nguyen, Shobha Regmi, Yoojin Seo, Simmyung Yook, Jee-Heon Jeong, Shiva Pathak, Inho Choi, Jun-Beom Park, Kyoung-Oh Doh, Dong-Mok Lee, Jong Oh Kim, Bieong-Kil Kim, Hyung Sik Kim, Ik-Jae Moon
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
BackgroundSystemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20–50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a promising a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f53804bddc161f44128b4fae680226
http://europepmc.org/articles/PMC6794806
http://europepmc.org/articles/PMC6794806
Autor:
Joo-Hyeung Nam, Young-Bae Seu, Bieong-Kil Kim, Ik-Jae Moon, Jong-Pil Kim, Soon-Bok Kim, Young-Hyun You
Publikováno v:
Journal of Life Science. 19:538-542
In this study, we confirmed water content and oxygen permeability of new polymeric materials synthesized from itaconic acid used for soft contact lenses. In this study, we polymerized materials for soft contact lenses using HEMA (2-hydroxyethyl metha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0943d839e33b5abaca80de5cb1ba5d6a
https://doi.org/10.5352/jls.2009.19.4.538
https://doi.org/10.5352/jls.2009.19.4.538
Autor:
Seong-Il Suh, Ik-Jae Moon, Byeong-Churl Chang, Kyung-Oh Doh, Jeong-Hoh Park, Yun-Han Lee, Arun K Bajpai, Jong-Gu Park, Hyun-Gu Kang
Publikováno v:
Oncogene. 24:6492-6501
Ribbon antisense (RiAS) to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. The antisense molecule, hTR-RiAS, combined with enhanced cellular uptake was shown to effectively inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc2d09fff171b3ed7a299f382804965
https://doi.org/10.1038/sj.onc.1208731
https://doi.org/10.1038/sj.onc.1208731
Autor:
Jong-Wook Park, Seok-Yong Uhm, Jong-Gu Park, Bin Hur, Kil-Hwan Han, Young Ho Kim, Yong-Joo Kim, Young-Bae Seu, Yun-Han Lee, Ik-Jae Moon, Jeong-Hoh Park, Koo-Jeong Kang
Publikováno v:
Nature Biotechnology. 23:591-599
Single-stranded genomic DNA of recombinant M13 phages was tested as an antisense molecule and examined for its usefulness in high-throughput functional genomics. cDNA fragments of various genes (TNF-alpha, c-myc, c-myb, cdk2 and cdk4) were independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10244077039ab5bcafed583316bc8b57
https://doi.org/10.1038/nbt1089
https://doi.org/10.1038/nbt1089
Autor:
Ik Jae Moon, Chun Sik Kwak, Je Ho Lee, Alan D. Schreiber, Jong-Gu Park, Kyu Sam Choi, Young Ik Lee
Publikováno v:
Biochemical Journal. 346:295-303
Systematic secondary structure simulation of a target mRNA sequence is shown to be effective for locating a good anti-sense target site. Multiple selected anti-sense sequences were placed in a single molecule. The anti-sense oligonucleotide (oligo) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ac4c090faa15b92943d5f0ec0070289
https://doi.org/10.1042/bj3460295
https://doi.org/10.1042/bj3460295
Potent Growth Inhibition of Leukemic Cells by Novel Ribbon-type Antisense Oligonucleotides to c-myb1
Autor:
Ji Eyon Kim, Young Kook Choi, Kyu Sam Choi, Jong-Gu Park, Young Ik Lee, Ik Jae Moon, Alan D. Schreiber
Publikováno v:
Journal of Biological Chemistry. 275:4647-4653
We studied the effects of antisense oligonucleotides (AS oligos) with a novel structure. The AS oligos were covalently closed to avoid exonuclease activities by enzymatic ligation of two identical molecules. The AS oligos of a ribbon type (RiAS oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895dca8a45f4a45cb830c9479ecf4cfe
https://doi.org/10.1074/jbc.275.7.4647
https://doi.org/10.1074/jbc.275.7.4647
Autor:
Jeong-Hoh Park, Ik-Jae Moon, Kil-Hwan Han, Jong-Pil Kim, Kyung-Oh Doh, Seok-Yong Uhm, Yun-Han Lee, Jong-Gu Park, Yun-Ui Bae
Publikováno v:
International Journal of Molecular Medicine. 25
In the present study, single-stranded large circular (LC)-sense molecules were utilized as probes for DNA microarrays and showed stronger binding signals than those of PCR-amplified cDNA probes. A microarray experiment using 284 LC-sense DNA probes f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308bf1e7b3af606749d41d93335e2a66
https://doi.org/10.3892/ijmm_00000320
https://doi.org/10.3892/ijmm_00000320
Autor:
Bieong-Kil Kim, Kyung-Oh Doh, Jong-Gu Park, Hyungu Kang, Joo Hyeung Nam, Young-Bae Seu, Ik-Jae Moon
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(11)
The new cholesterol-based cationic lipids B, C, and D with an ether linked spacer were synthesized by using aminopropyl chain extension with acrylonitrile. The cholesterol-based cationic lipid A with carbamoyl linkage were also synthesized in order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a5dda0a566ba5d0da09fb6d613a7f1
https://pubmed.ncbi.nlm.nih.gov/19409781
https://pubmed.ncbi.nlm.nih.gov/19409781
Publikováno v:
International Journal of Molecular Medicine.
Transforming growth factor-beta1 (TGF-beta1) is an important mediator of tissue fibrosis, including liver cirrhosis. Ribbon-type antisense oligonucleotide to TGF-beta1 (TGF-beta1 RiAS) was designed and combined with cationic peptide derived from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f4b3c14e1ae3eb98fe1402346a36c6
https://doi.org/10.3892/ijmm.21.1.33
https://doi.org/10.3892/ijmm.21.1.33