A bcr-v-abl oncogene induces lymphomas in transgenic mice

Autor: Ik, Hariharan, Aw, Harris, Crawford M, Abud H, Webb E, Cory S, Jerry Adams

Publikováno v: Europe PubMed Central

In chronic myeloid leukemia and some cases of acute lymphoblastic leukemia, a 9;22 chromosome translocation has fused most of the c-abl oncogene to a gene designated bcr. To explore in vivo the biological effects of the chimeric gene, we introduced a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a139c953c37df324e8fc037462271281
https://pubmed.ncbi.nlm.nih.gov/2789335

bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia

Autor: Ik, Hariharan, Jerry Adams, Cory S

Publikováno v: Europe PubMed Central

In chronic myeloid leukemia (CML), a chromosome translocation has fused the bcr gene to the c-abl oncogene, such that a chimeric bcr-abl polypeptide can be made. To explore the biological properties of bcr-abl and compare them with those of the Abels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e4620af498c562112a8bd0e338faf69f
http://europepmc.org/abstract/med/3147434

Coordinated growth of linked epithelia is mediated by the Hippo pathway.

Autor: Friesen S; Department of Molecular and Cell Biology, University of California, Berkeley., Hariharan IK; Department of Molecular and Cell Biology, University of California, Berkeley.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 17. Date of Electronic Publication: 2023 Mar 17.

Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs.

Autor: Worley MI; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. Electronic address: mworley@berkeley.edu., Everetts NJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA; Department of Electrical Engineering and Computer Science, Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA., Yasutomi R; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Chang RJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Saretha S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Yosef N; Department of Electrical Engineering and Computer Science, Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA. Electronic address: niryosef@berkeley.edu., Hariharan IK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. Electronic address: ikh@berkeley.edu.

Publikováno v: Current biology : CB [Curr Biol] 2022 Aug 08; Vol. 32 (15), pp. 3350-3364.e6. Date of Electronic Publication: 2022 Jul 11.

Single-cell transcriptomics of the Drosophila wing disc reveals instructive epithelium-to-myoblast interactions.

Autor: Everetts NJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Department of Electrical Engineering & Computer Science, Center for Computational Biology, UC Berkeley, University of California, Berkeley, Berkeley, United States., Worley MI; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Yasutomi R; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Yosef N; Department of Electrical Engineering & Computer Science, Center for Computational Biology, UC Berkeley, University of California, Berkeley, Berkeley, United States., Hariharan IK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.

Publikováno v: ELife [Elife] 2021 Mar 22; Vol. 10. Date of Electronic Publication: 2021 Mar 22.