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of 603
pro vyhledávání: '"Ijzerman, A.P."'
Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism
Autor:
den Hollander, L.S., Béquignon, O.J.M., Wang, X., van Wezel, K., Broekhuis, J., Gorostiola González, M., de Visser, K.E., IJzerman, A.P., van Westen, G.J.P., Heitman, L.H.
Publikováno v:
In Biochemical Pharmacology February 2023 208
Publikováno v:
In Biochemical Pharmacology 15 October 2016 118:88-95
Autor:
Hillger, J.M., Diehl, C., van Spronsen, E., Boomsma, D.I., Slagboom, P.E., Heitman, L.H., IJzerman, A.P.
Publikováno v:
In Biochemical Pharmacology 1 September 2016 115:114-122
Publikováno v:
In Biosensors and Bioelectronics 15 May 2016 79:721-727
Akademický článek
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Autor:
Bongers, B.J., Sijben, H.J., Hartog, P.B.R., Tarnovskiy, A., IJzerman, A.P., Heitman, L.H., Westen, G.J.P. van
Publikováno v:
Journal of Chemical Information and Modeling, 63(6):1745-1755
Solute carriers (SLCs) are relatively underexplored compared to other prominent protein families such as kinases and G protein-coupled receptors. However, proteins from the SLC family play an essential role in various diseases. One such SLC is the hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f737d4ed6a1e883f259e2d9036d42e49
https://doi.org/10.1021/acs.jcim.2c01645
https://doi.org/10.1021/acs.jcim.2c01645
Publikováno v:
Journal of Cheminformatics, 15(1):24
Rational drug design often starts from specific scaffolds to which side chains/substituents are added or modified due to the large drug-like chemical space available to search for novel drug-like molecules. With the rapid growth of deep learning in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c48699d94b7f5098883f4e3883af82b
https://doi.org/10.1186/s13321-023-00694-z
https://doi.org/10.1186/s13321-023-00694-z
Autor:
Béquignon, O.J.M., Bongers, B.J., Jespers, W., IJzerman, A.P., Water, B. van de, Westen, G.J.P. van
Publikováno v:
Journal of cheminformatics, 15(1):3
With the ongoing rapid growth of publicly available ligand–protein bioactivity data, there is a trove of valuable data that can be used to train a plethora of machine-learning algorithms. However, not all data is equal in terms of size and quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b7bd35ba8253f42a45bc291627f436
https://doi.org/10.1186/s13321-022-00672-x
https://doi.org/10.1186/s13321-022-00672-x
Autor:
den Hollander, L.S., Béquignon, O.J.M., Wang, X., van Wezel, K., Broekhuis, J., Gorostiola González, M., de Visser, K.E., IJzerman, A.P., van Westen, G.J.P., Heitman, L.H.
Publikováno v:
In Biochemical Pharmacology March 2023 209
Publikováno v:
GPCRs as therapeutic targets, 631-676. John Wiley & Sons
STARTPAGE=631;ENDPAGE=676;TITLE=GPCRs as therapeutic targets
STARTPAGE=631;ENDPAGE=676;TITLE=GPCRs as therapeutic targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b51e4d141c3ba2e1eba3cf6ca5bb0c
https://doi.org/10.1002/9781119564782.ch18
https://doi.org/10.1002/9781119564782.ch18