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Autor:
Junghwa Lee, Kyungmin Lee, Hyeonjin Bae, Kunhee Lee, Solhwi Lee, Junhui Ma, Kyungjo Jo, Ijun Kim, ByulA Jee, Minyong Kang, Se Jin Im
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In chronic infections and cancer, exhausted CD8 T cells exhibit heterogeneous subpopulations. TCF1+PD-1+ progenitor exhausted CD8 T cells (Tpex) can self-renew and give rise to Tim-3+PD-1+ terminally differentiated CD8 T cells that retain their effec
Externí odkaz:
https://doaj.org/article/2a80f01110ac4e05b51841e2cd95b494