Výsledky vyhledávání - "Ijeoma Okeigwe"

Progesterone receptor integrates the effects of mutated MED12 and altered DNA methylation to stimulate RANKL expression and stem cell proliferation in uterine leiomyoma

Autor: Shimeng Liu, Serdar E. Bulun, Ijeoma Okeigwe, Stacy A. Kujawa, John S. Coon, Ping Yin

Publikováno v: Oncogene

Progesterone and its receptor, PR, are essential for uterine leiomyoma (LM, a.k.a., fibroid) tumorigenesis, but the underlying cellular and molecular mechanisms remain unclear. The receptor activator of NF-κB (RANKL) was recently identified as a nov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08099bf579a1e79e037610d08cb3a54
https://doi.org/10.1038/s41388-018-0612-6

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Assessing the impact of delayed blastulation using time lapse morphokinetics and preimplantation genetic testing in an IVF patient population

Autor: Edmond Confino, Ijeoma Okeigwe, Dana Kimelman, Lee P. Shulman, Rafael Confino, John Zhang, Jaclyn C. Lambe-Steinmiller, Mary Ellen Pavone

Publikováno v: J Assist Reprod Genet

PURPOSE: There is clinical evidence that early cleavage timing parameters predictive of blastocyst development also correlate with embryo implantation potential. The aim of this study is to determine the developmental competency of embryos with delay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa96e104cc4b96b51d05f508121a3e2
https://europepmc.org/articles/PMC6707988/

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PLIN2 Functions as a Novel Link between Progesterone Signaling and Metabolism in Uterine Leiomyoma Cells

Autor: Shimeng Liu, Jared C. Robins, Ijeoma Okeigwe, Serdar E. Bulun, Alfred Rademaker, Ping Yin, John S. Coon, Stacy A. Kujawa

Publikováno v: J Clin Endocrinol Metab

Context Uterine leiomyoma (fibroids) are the most common tumors in women. Recently, perilipin-2 (PLIN2) was identified as a critical target gene of the progesterone receptor; however, its function in the pathogenesis of fibroids is unknown. Objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75376720e8edd653703b1638f2e12f1e
https://doi.org/10.1210/jc.2019-00762

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5-Alpha reductase deficiency

Autor: Ijeoma Okeigwe, Wendy Kuohung

Publikováno v: Current Opinion in Endocrinology, Diabetes & Obesity. 21:483-487

5-Alpha reductase is an enzyme responsible for the conversion of testosterone to dihydrotestosterone. This key enzyme is responsible for triggering masculinization of the male external genitalia. Discovery of 5-alpha reductase deficiency as a syndrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665bfca47e9cb7a086100bb283028672
https://doi.org/10.1097/med.0000000000000116

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Physician-scientists in obstetrics and gynecology: predictors of success in obtaining independent research funding

Autor: Wendy Kuohung, Linda J. Heffner, Cynthia Wang, Ijeoma Okeigwe, Joseph A. Politch

Publikováno v: American journal of obstetrics and gynecology. 217(1)

Background Obstetrics and gynecology departments receive the smallest amount of National Institutes of Health research funding and have significantly lower application success rates compared to pediatric, internal medicine, and surgery departments. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b728d4002f8209a7d4d8859a6f1d9c4
https://pubmed.ncbi.nlm.nih.gov/28315665

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Racial/Ethnic Differences in Women’s Experiences with Symptomatic Uterine Fibroids: A Qualitative Assessment

Autor: Marissa S. Ghant, Katherine S. Sengoba, Ijeoma Okeigwe, Erica E. Marsh, G. Mendoza

The purpose of this study is to determine racial/ethnic differences in treatment experiences and expectations among women with fibroids. Sixty women with symptomatic uterine fibroids completed semi-structured interviews, demographic surveys, and a he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0268ba80ae11faa9fcde68843e901
https://europepmc.org/articles/PMC5064808/

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The effect of HAART and calendar period on Kaposi's sarcoma and non-Hodgkin lymphoma: results of a match between an AIDS and cancer registry

Autor: Susan Scheer, Sharon Pipkin, David Harris, Nancy A. Hessol, Ijeoma Okeigwe, Sandra Schwarcz

Publikováno v: AIDS. 25:463-471

Objectives: To assess the impact of HAART use on AIDS-defining Kaposi’s sarcoma and non-Hodgkin lymphoma (NHL) among adults with AIDS. Design: Registry linkage study. Methods: Adults diagnosed with AIDS from 1990 to 2000 in the San Francisco AIDS c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509867e167eb89cbe09558671e99a83c
https://doi.org/10.1097/qad.0b013e32834344e6

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