Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ijeoma E. Obi"'
Autor:
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined
Externí odkaz:
https://doaj.org/article/0cb3e71087914936a984fb5185dc2cdf
Autor:
Eman Y. Gohar, Elizabeth M. Daugherty, Jeffrey O. Aceves, Randee Sedaka, Ijeoma E. Obi, J. Miller Allan, Reham H. Soliman, Chunhua Jin, Carmen De Miguel, Sarah H. Lindsey, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 10 (2020)
Background The novel estrogen receptor, G‐protein–coupled estrogen receptor (GPER), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there i
Externí odkaz:
https://doaj.org/article/04ff94a8dd55461fb187cedf3a1e54e3
Autor:
Stephen R. Aldous, Colton E. Remedies, Edward W. Inscho, Paul W. Sanders, Zhengrong Guan, Wenguang Feng, Ijeoma E. Obi, Samia I Meera
Publikováno v:
Am J Physiol Renal Physiol
Renal autoregulation is critical in maintaining stable renal blood flow (RBF) and glomerular filtration rate (GFR). Renal ischemia-reperfusion (IR)-induced kidney injury is characterized by reduced RBF and GFR. The mechanisms contributing to renal mi
Autor:
Dingguo Zhang, Joshua S. Speed, John Miller Allan, Chunhua Jin, Megan K Rhoads, David M. Pollock, Reham H Soliman, Jennifer S. Pollock, Ijeoma E. Obi, Randee Sedaka, Binli Tao
Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F710-F719
Kidney function follows a 24-h rhythm subject to regulation by circadian genes including the transcription factor Bmal1. A high-salt diet induces a phase shift in Bmal1 expression in the renal inner medulla that is dependent on endothelin type B (ETB
Autor:
Joshua S. Speed, Jennifer S. Pollock, Carmen De Miguel, Analia S. Loria, Bryan K. Becker, David M. Pollock, Frank T. Spradley, Ijeoma E. Obi
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 315:R1085-R1095
Clinical studies have shown that obesity negatively impacts large arteries’ function. We reported that rats exposed to maternal separation (MatSep), a model of early life stress, display enhanced angiotensin II (ANG II)-induced vasoconstriction in
Autor:
Jeffrey O. Aceves, Chunhua Jin, Eman Y. Gohar, Carmen De Miguel, Sarah H. Lindsey, Jennifer S. Pollock, Reham H Soliman, Ijeoma E. Obi, Randee Sedaka, David M. Pollock, Elizabeth M. Daugherty, J. Miller Allan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The novel estrogen receptor, G‐protein–coupled estrogen receptor ( GPER ), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there
Autor:
Bryan K. Becker, David M. Pollock, Chunhua Jin, Ijeoma E. Obi, Pengyuan Liu, Joshua S. Speed, Eman Y. Gohar, Jermaine G. Johnston, Jennifer S. Pollock, Tanecia Mitchell, Carmen De Miguel, Alison J. Kriegel, Elizabeth M. Daugherty
Publikováno v:
The FASEB Journal. 33
Autor:
Jennifer S. Pollock, Elizabeth M. Daugherty, Malgorzata Kasztan, Carmen De Miguel, Eman Y. Gohar, Ijeoma E. Obi, David M. Pollock
Publikováno v:
The FASEB Journal. 32
Publikováno v:
The FASEB Journal. 32
Publikováno v:
American journal of physiology. Renal physiology. 314(3)
Early life stress (ELS) in humans is associated with elevated proinflammatory markers. We hypothesized that ELS induces activation of the immune response in a rat model of ELS, maternal separation (MatSep), in adulthood. MatSep involves separating pu