Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K

Autor: Marquis, R. W., Ru, Y., Yamashita, D. S., Oh, H.-J., Yen, J., Thompson, S. K., Carr, T. J., Levy, M. A., Tomaszek, T. A., Ijames, C. F.

Publikováno v: Bioorganic & Medicinal Chemistry; 1999, Vol. 7 Issue: 4 p581-588, 8p

Harbinatic Acid, a Novel and Potent DNA Polymerase β Inhibitor from Hardwickia binata

Autor: Deng, J.-Z., Starck, S. R., Hecht, S. M., Ijames, C. F., Hemling, M. E.

Publikováno v: Journal of Natural Products; July 23, 1999, Vol. 62 Issue: 7 p1000-1002, 3p

Mechanism of inhibition of cathepsin K by potent, selective 1, 5-diacylcarbohydrazides: a new class of mechanism-based inhibitors of thiol proteases.

Autor: Bossard MJ; Departments of Molecular Recognition, Physical and Structural Chemistry, and Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, P.O. Box 1539, King of Prussia, Pennsylvania 19406, USA., Tomaszek TA, Levy MA, Ijames CF, Huddleston MJ, Briand J, Thompson S, Halpert S, Veber DF, Carr SA, Meek TD, Tew DG

Publikováno v: Biochemistry [Biochemistry] 1999 Nov 30; Vol. 38 (48), pp. 15893-902.

Design of potent and selective human cathepsin K inhibitors that span the active site.

Autor: Thompson SK; Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, King of Prussia, PA 19406, USA., Halbert SM, Bossard MJ, Tomaszek TA, Levy MA, Zhao B, Smith WW, Abdel-Meguid SS, Janson CA, D'Alessio KJ, McQueney MS, Amegadzie BY, Hanning CR, DesJarlais RL, Briand J, Sarkar SK, Huddleston MJ, Ijames CF, Carr SA, Garnes KT, Shu A, Heys JR, Bradbeer J, Zembryki D, Lee-Rykaczewski L, James IE, Lark MW, Drake FH, Gowen M, Gleason JG, Veber DF

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1997 Dec 23; Vol. 94 (26), pp. 14249-54.

Comparative study of photodissociation and surface-induced dissociation by laser desorption Fourier transform mass spectrometry.

Autor: Castoro JA; Department of Chemistry, University of California, Riverside 92521., Nuwaysir LM, Ijames CF, Wilkins CL

Publikováno v: Analytical chemistry [Anal Chem] 1992 Oct 01; Vol. 64 (19), pp. 2238-43.