Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Iiro Rajantie"'
Autor:
Marko Uutela, Kari Alitalo, Helge Wiig, Maria Wirzenius, Karri Paavonen, Terhi Karpanen, Ulf Eriksson, Marja Lohela, Yulong He, Katri Pajusola, Petri Salven, Iiro Rajantie
Publikováno v:
Blood. 104:3198-3204
Platelet-derived growth factor-D (PDGF-D) is a recently characterized member of the PDGF family with unknown in vivo functions. We investigated the effects of PDGF-D in transgenic mice by expressing it in basal epidermal cells and then analyzed skin
Publikováno v:
Molecular Biology of the Cell. 15:4226-4233
The Bmx gene, a member of the Tec family of nonreceptor protein tyrosine kinases, is expressed in arterial endothelium and in certain hematopoietic and epithelial cells. Previous in vitro studies have implicated Bmx signaling in cell migration and su
Autor:
Yulong He, Petri Salven, Marika J. Karkkainen, Iiro Rajantie, Maritta Ilmonen, Paula Haiko, Kari Alitalo, Taija Makinen
Publikováno v:
Cancer Research. 64:3737-3740
Endothelial progenitor cells have been shown to contribute to angiogenesis in various tumor models. Here, we have studied the relative contributions of bone marrow (BM)-derived endothelial progenitors and pre-existing lymphatic vessels to tumor lymph
Publikováno v:
ResearcherID
Tec family kinases have important roles in lymphocytes; however, little is known about their function in monocytes/macrophages. In this study we report that Tec family kinases are essential for M-CSF (M-CSF)-induced signaling pathways that regulate m
Autor:
Nina Kaskenpää, Kari Alitalo, Derrick J. Rossi, Seppo Ylä-Herttuala, Iiro Rajantie, Irving L. Weissman, Susanna Purhonen, Petri Salven, Jarmo Palm
The mechanisms by which bone marrow (BM)-derived stem cells might contribute to angiogenesis and the origin of neovascular endothelial cells (ECs) are controversial. Neovascular ECs have been proposed to originate from VEGF receptor 2-expressing (VEG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647009856dbb7aefde0c2c1438506a6f
https://europepmc.org/articles/PMC2365563/
https://europepmc.org/articles/PMC2365563/
Autor:
Peter Carmeliet, Petri Salven, Yun He, William C. Sessa, Kari Alitalo, Albert J. Sinusas, Wolfgang Schaper, Rong Zhang, Iiro Rajantie, Shibo Tang, Hongbo Chi, Wang Min, Xianghong Li, Matthias Heil, Dianhong Luo, Jun Yu, Yan Luo
Publikováno v:
The Journal of clinical investigation. 116(9)
Bmx/Etk non-receptor tyrosine protein kinase has been implicated in endothelial cell migration and tube formation in vitro. However, the role of Bmx in vivo is not known. Bmx is highly induced in the vasculature of ischemic hind limbs. We used both m
Autor:
Kari Alitalo, Thomas Harding, Takashi Takahashi, Yulong He, Iiro Rajantie, Tanja Holopainen, Seppo Ylä-Herttuala, Karin Jooss, Katri Pajusola, Michael Jeltsch
Publikováno v:
Cancer research. 65(11)
Lymphangiogenic growth factors vascular endothelial growth factor (VEGF)-C and VEGF-D have been shown to promote lymphatic metastasis by inducing tumor-associated lymphangiogenesis. In this study, we have investigated how tumor cells gain access into
Publikováno v:
Blood. 104(7)
Bone marrow (BM)-derived cells are thought to participate in the growth of blood vessels during postnatal vascular regeneration and tumor growth, a process previously attributed to stem and precursor cells differentiating to endothelial cells. We use
Autor:
Pipsa Saharinen, Niklas Ekman, Olli Silvennoinen, Elena Arighi, Iiro Rajantie, Ari Ristimäki, Kari Alitalo
Publikováno v:
Oncogene. 19(36)
Cytoplasmic protein tyrosine kinases play crucial roles in signaling via a variety of cell surface receptors. The Bmx tyrosine kinase, a member of the Tec family, is expressed in hematopoietic cells of the granulocytic and monocytic lineages. Here we
Autor:
Karri, Paavonen, Niklas, Ekman, Maria, Wirzenius, Iiro, Rajantie, Matti, Poutanen, Kari, Alitalo
Publikováno v:
Molecular Biology of the Cell; September 2004, Vol. 15 Issue: 9 p4226-33, 8p