Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Iikki Donner"'
Autor:
Lauri J. Sipilä, Riku Katainen, Mervi Aavikko, Janne Ravantti, Iikki Donner, Rainer Lehtonen, Ilmo Leivo, Henrik Wolff, Reetta Holmila, Kirsti Husgafvel-Pursiainen, Lauri A. Aaltonen
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-13 (2024)
Abstract Background Sinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the non-intestinal-type sinonasal adenocarcinoma (non-ITAC). Occurrence of ITAC is strongly as
Externí odkaz:
https://doaj.org/article/13bdffe712f4463f8322241bddd8c7e2
Autor:
Matti Janhunen, Aslak Eronen, Jukka Kekäläinen, Craig R. Primmer, Iikki Donner, Pekka Hyvärinen, Hannu Huuskonen, Raine Kortet
Publikováno v:
Evolutionary Applications, Vol 17, Iss 4, Pp n/a-n/a (2024)
Abstract Endangered wild fish populations are commonly supported by hatchery propagation. However, hatchery‐reared fish experience very different selective pressures compared to their wild counterparts, potentially causing genotype‐by‐environme
Externí odkaz:
https://doaj.org/article/f0ede91e38bb4ffd8d73a976241ca795
Autor:
Hande Demir, Iikki Donner, Leena Kivipelto, Outi Kuismin, Camilla Schalin-Jäntti, Ernesto De Menis, Auli Karhu
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109897 (2014)
Pituitary adenomas are neoplasms of the anterior pituitary lobe and account for 15-20% of all intracranial tumors. Although most pituitary tumors are benign they can cause severe symptoms related to tumor size as well as hypopituitarism and/or hypers
Externí odkaz:
https://doaj.org/article/d070a9297e854165afde32fb57a2f599
Autor:
Andrew H. House, Paul V. Debes, Minna Holopainen, Reijo Käkelä, Iikki Donner, Morgane Frapin, Ehsan Pashay, Johanna Kurko, Hanna Ruhanen, Craig R. Primmer
Seasonality can influence many physiological traits requiring optimal energetic capacity for life-history stage transitions. In Atlantic salmon, high-energy status is essential for the initiation of maturation. Atlantic salmon lipid reserves are pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d413eb884c4b0c30a61df6667b27aec
https://doi.org/10.1101/2023.02.22.529528
https://doi.org/10.1101/2023.02.22.529528
Autor:
Riku Katainen, Roosa-Maria Plaketti, Juho Kariniemi, Outi Kuismin, Pekka Romsi, Linda M. Forsström, Mervi Aavikko, Anna Kuosmanen, Iikki Donner, Lauri A. Aaltonen, Lauri J. Sipilä
Publikováno v:
Vascular. 30:842-847
Background Visceral artery aneurysms (VAAs) can be fatal if ruptured. Although a relatively rare incident, it holds a contemporary mortality rate of approximately 12%. VAAs have multiple possible causes, one of which is genetic predisposition. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbe6fbc8b71cf8bed6dfce5597d78b5
https://doi.org/10.1177/17085381211033157
https://doi.org/10.1177/17085381211033157
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 275:111337
Age at maturity is a key life history trait and a significant contributor to life history strategy variation. The maturation process is complex and influenced by genetic and environmental factors alike, but specific causes of variation in maturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6df0cd29148f79600f414b00b1e7a5
https://doi.org/10.1016/j.cbpa.2022.111337
https://doi.org/10.1016/j.cbpa.2022.111337
Autor:
Riku, Katainen, Iikki, Donner, Maritta, Räisänen, Davide, Berta, Anna, Kuosmanen, Eevi, Kaasinen, Marja, Hietala, Lauri A, Aaltonen
Publikováno v:
Journal of medical genetics. 59(7)
Genes involved in epigenetic regulation are central for chromatin structure and gene expression. Specific mutations in these might promote carcinogenesis in several tissue types.We used exome, whole-genome and Sanger sequencing to detect rare variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf8111c58b2c6f49a78e6a1b01b5a2b7
https://pubmed.ncbi.nlm.nih.gov/34281993
https://pubmed.ncbi.nlm.nih.gov/34281993
Autor:
Ilkka Heiskanen, Pekka Katajisto, Päivi Pihlajamaa, Pia Vahteristo, Camilla Schalin-Jäntti, Olli Carpén, Lauri A. Aaltonen, Noora Andersson, Lauri J. Sipilä, Jussi Taipale, Riku Katainen, Iikki Donner, Simona Bramante, Päivi Sulo, Nalle Pentinmikko, Kaisa Lehti, Anna Kuosmanen, Erika Gucciardo, Johanna Arola, Mervi Aavikko, Eevi Kaasinen, Jukka-Pekka Mecklin, Samantha Martin, Ari Ristimäki
Publikováno v:
Human Molecular Genetics
Many hereditary cancer syndromes are associated with an increased risk of small and large intestinal adenocarcinomas. However, conditions bearing a high risk to both adenocarcinomas and neuroendocrine tumors are yet to be described. We studied a fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5b0080e1acc11c147c2829754d8692
http://urn.fi/URN:NBN:fi:jyu-202202091457
http://urn.fi/URN:NBN:fi:jyu-202202091457
Publikováno v:
Lung Cancer. 122:76-82
Objectives Although the primary cause of lung cancer is smoking, a considerable proportion of all lung cancers occur in never smokers. Gender influences the risk and characteristics of lung cancer and women are overrepresented among never smokers wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2894a93afa79d9c8e63daa27acbf44d6
https://doi.org/10.1016/j.lungcan.2018.05.027
https://doi.org/10.1016/j.lungcan.2018.05.027
Autor:
Iikki Donner, Tatiana Cajuso, Riku Katainen, Eevi Kaasinen, Kimmo Palin, Esa Pitkänen, Lauri A. Aaltonen, Veli Mäkinen
Publikováno v:
Nature Protocols
Next-generation sequencing (NGS) is routinely applied in life sciences and clinical practice, but interpretation of the massive quantities of genomic data produced has become a critical challenge. The genome-wide mutation analyses enabled by NGS have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec2a3aa46460d5226d0322897d16341
https://pubmed.ncbi.nlm.nih.gov/30323186
https://pubmed.ncbi.nlm.nih.gov/30323186