Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ihar Seviaryn"'
Publikováno v:
Molecular Biology Reports. 46:1343-1348
Radiation induces DNA and protein damage and free radical formation, effectively establishing cellular senescence in a variety of models. We demonstrate the effects of two known pleiotropic drugs following gamma radiation damage in neurosphere/cerebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc561d1f95036d8e7fc239885a483e4
https://doi.org/10.1007/s11033-018-4552-6
https://doi.org/10.1007/s11033-018-4552-6
Autor:
Vladimir A. Kulchitsky, Ihar Seviaryn, A. Chernov, Dzmitry Shcharbin, Volha Dzmitruk, Jean-Pierre Majoral, Natalya Goncharova, Anne-Marie Caminade, M. P. Potapnev, Maria Bryszewska, Antos Shakhbazau, S. M. Kosmacheva, E. Pedziwiatr-Werbicka, M. Talabaev
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 3, Iss 3, Pp 458-473 (2011)
Pharmaceutics; Volume 3; Issue 3; Pages: 458-473
Pharmaceutics, Vol 3, Iss 3, Pp 458-473 (2011)
Pharmaceutics; Volume 3; Issue 3; Pages: 458-473
Research concerning new targeting delivery systems for pharmacologically active molecules and genetic material is of great importance. The aim of the present study was to investigate the potential of fourth generation (P4) cationic phosphorus-contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23415351f3b6c596e1d5b22eeae79798
https://doi.org/10.3390/pharmaceutics3030458
https://doi.org/10.3390/pharmaceutics3030458
Autor:
Ranjan Kumar, Natalya Goncharova, M. P. Potapnev, Jeff Biernaskie, Ihar Seviaryn, S. M. Kosmacheva, Rajiv Midha, Antos Shakhbazau, Dzmitry Shcharbin, Maria Bryszewska
Publikováno v:
Molecular pharmaceutics. 9(5)
This study reports the use of a nonviral expression system based on polyamidoamine dendrimers for time-restricted neurotrophin overproduction in mesenchymal stem cells and skin precursor-derived Schwann cells. The dendrimers were used to deliver plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b8a8ab9ce990c007d7fa83235acc56
https://pubmed.ncbi.nlm.nih.gov/22480259
https://pubmed.ncbi.nlm.nih.gov/22480259
Publikováno v:
Bulletin of experimental biology and medicine. 151(1)
Conditions of human BM and umbilical cord blood MSC in vitro differentiation in the hepatogenic direction were studied. Changes in cell morphology, phenotype, acquisition of the capacity to produce albumin and accumulate glycogen, express cytokeratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d916cbda654e14254e94220a2c99062
https://pubmed.ncbi.nlm.nih.gov/22442820
https://pubmed.ncbi.nlm.nih.gov/22442820
Autor:
Dzmitry Shcharbin, Maria Bryszewska, M. P. Potapnev, Natalya Goncharova, Ihar Seviaryn, S. M. Kosmacheva, N. A. Kartel, Antos Shakhbazau, Jean-Pierre Majoral
Publikováno v:
Bulletin of experimental biology and medicine. 151(1)
Expression of transgenes in neurons and stromal/mesenchymal stem cells (MSC) can greatly enhance their therapeutic potential. In transfection experiments, we studied properties of linear and branched (dendrimers) polycations as transgene delivery veh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80619cebbbcc678b534c587dde70b6ae
https://pubmed.ncbi.nlm.nih.gov/22442817
https://pubmed.ncbi.nlm.nih.gov/22442817
Autor:
Maria Bryszewska, S. M. Kosmacheva, Ihar Seviaryn, Michael S. Kallos, Ranjan Kumar, M. P. Potapnev, Natalya Goncharova, Dzmitry Shcharbin, Rajiv Midha, Holly M. Wobma, Antos Shakhbazau
Publikováno v:
Current medicinal chemistry. 19(32)
Genetic engineering of stem cells and their derivatives has the potential to enhance their regenerative capabilities. Here, dendrimer- and lipofection-based approaches were used for non-viral neurotrophin-3 (NT-3) over-expression in Schwann cells dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe1bbdf061992584cf60436e8f1fe46
https://pubmed.ncbi.nlm.nih.gov/22834817
https://pubmed.ncbi.nlm.nih.gov/22834817
Autor:
Barbara Gabara, Maria Bryszewska, Ihar Seviaryn, Maxim Ionov, S. M. Kosmacheva, M. P. Potapnev, Dzmitry Shcharbin, Antos Shakhbazau, Natalya Goncharova
Publikováno v:
Molecular biology reports. 37(4)
We report the use of polyamidoamine (PAMAM-NH(2)) dendrimers along with other non-viral vehicles for the in vitro transfection of human bone marrow mesenchymal stem cells (hMSCs) and for engineering MSCs to secrete brain-derived neurotrophic factor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332e2cf8fd2d9ec2e44899b0d9cf64e2
https://pubmed.ncbi.nlm.nih.gov/19649724
https://pubmed.ncbi.nlm.nih.gov/19649724
Autor:
M. P. Potapnev, Ihar Seviaryn, Natalya Goncharova, Dzmitry Shcharbin, Iauhenia Isayenka, Nikolai Kartel, S. M. Kosmacheva, Antos Shakhbazau, Maria Bryszewska
Publikováno v:
International journal of pharmaceutics. 383(1-2)
Dendriplexes were characterized by ethidium bromide intercalation assay and their transfection efficiency was studied using HEK 293 cells and human mesenchymal stem cells. PAMAM G4 showed a higher transfection efficiency than PAMAM G3–G6, G4-OH, G4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bde3d1ecafd2b270279e136299aefa
https://pubmed.ncbi.nlm.nih.gov/19770028
https://pubmed.ncbi.nlm.nih.gov/19770028