Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Igor Zupanets"'
Publikováno v:
ScienceRise: Pharmaceutical Science, Iss 4(32), Pp 67-77 (2021)
The aim.To develop conceptual framework of the strategy for a reasonable transition from original to generic medicines by complex implementation of proper bioequivalence studies and sufficient therapeutic drug monitoring management. Materials and met
Publikováno v:
Journal of Bioequivalence & Bioavailability.
Publikováno v:
Europe PubMed Central
Macrolides is one of the most interesting and promising classes of antibiotics, which occupy one of the first places in the world in the frequency of clinical use. In recent years, new facts have reported about specific features of the mechanism of a
Autor:
Vp, Chernykh, Lp, Abramova, Li, Boriak, Vn, Goncharova, Lv, Belogurova, Igor Zupanets, Vi, Makurina
Publikováno v:
Europe PubMed Central
The experiments on 6-Gy irradiated rats have revealed that the new biologically active substance. Glucosuccine has a radioprotective effect which depends upon the route of administration. The agent was demonstrated to produce a profound radioprotecti
Publikováno v:
Europe PubMed Central
The effects of glycosamine aminosugar on the processes of endotoxicosis and lipid peroxidation were thoroughly studied in rats with toxic pulmonary edema. There was a glycosamine-induced decrease in markers of endotoxicosis, such as medium-weight mol
Publikováno v:
Europe PubMed Central
Publikováno v:
Europe PubMed Central
The study of the antiexudative activities of voltaren, indomethacin and piroxicam in combination with glucosamine on the model of carrageenan inflammation showed that the combination makes it possible to decrease the effective doses of nonsteroidal a
Publikováno v:
Europe PubMed Central
The antioxidant and membrane-stabilizing activities of D-glucosamine were studied on two models of toxic liver damage. When administered in a dose of 50 mg/kg, D-glucosamine was found to prevent the development of the hepatocyte cytolysis syndrome, t
Publikováno v:
Europe PubMed Central
The paper reviews the present state of the problem on the physiological importance of D-(+)-glucosamine, an amino sugar. Glucosamine is shown to be a component of many biological important systems widely spread in nature. It is a part of the connecti
Publikováno v:
Europe PubMed Central
The hepatotropic effect of nonsteroidal anti-inflammatory drugs (NSAID) such as indomethacin, voltaren, piroxicam, phenylbutazon, mefenamic acid was studied. It was found that according to their level of the pharmacological protection of the liver ag