Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Igor V. Kizub"'
Autor:
Dariia O. Dryn, Mariia I. Melnyk, Donal Melanaphy, Igor V. Kizub, Christopher D. Johnson, Alexander V. Zholos
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 759 (2023)
TRP channels are expressed both in vascular myocytes and endothelial cells, but knowledge of their operational mechanisms in vascular tissue is particularly limited. Here, we show for the first time the biphasic contractile reaction with relaxation f
Externí odkaz:
https://doaj.org/article/7a03f16061844a55a288f33d49a783fd
Autor:
Joseph M. Miano, Sachin A. Gupte, Igor V. Kizub, Kevin Michael, Petra Rocic, Michael Grzybowski, Atsushi Kitagawa, Christina Jacob, Aron M. Geurts, Rakhee S. Gupte, Julie A. Reisz, Angelo D'Alessandro
Publikováno v:
Hypertension. 76:523-532
Epidemiological studies suggest that individuals in the Mediterranean region with a loss-of-function, nonsynonymous single nucleotide polymorphism (S188F), in glucose-6-phosphate dehydrogenase ( G6pd ) are less susceptible to vascular diseases. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59f0a9d46d372f6a7747c6aea57e8f7
https://doi.org/10.1161/hypertensionaha.120.14772
https://doi.org/10.1161/hypertensionaha.120.14772
Autor:
Igor V. Kizub, Anatoly Soloviev
Publikováno v:
Biochemical Pharmacology. 159:121-139
Ionizing radiation (IR) leads to a variety of the cardiovascular diseases, including the arterial hypertension. A number of studies have demonstrated that blood vessels represent important target for IR, and the endothelium is one of the most vulnera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c492c2487805493a1beba92c4260c3
https://doi.org/10.1016/j.bcp.2018.11.019
https://doi.org/10.1016/j.bcp.2018.11.019
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b84fdef6041184e4ac919c949796caa7
https://doi.org/10.1096/fasebj.2019.33.1_supplement.827.1
https://doi.org/10.1096/fasebj.2019.33.1_supplement.827.1
Dehydroepiandrosterone (DHEA) is an adrenal steroid hormone, which has the highest serum concentration among steroid hormones with DHEA sulfate (DHEAS). DHEA possesses an inhibitory action on glucose-6-phosphate dehydrogenase (G6PD), the first pentos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5f2115e6db649cb673dd53a3206c6c
https://europepmc.org/articles/PMC6336967/
https://europepmc.org/articles/PMC6336967/
Autor:
Jeremy P.T. Ward, Ievgen V. Strielkov, Igor V. Kizub, Silke Becker, Jesus Prieto-Lloret, Anatoly Soloviev, Yasin Shaifta, Philip I. Aaronson, Vladimir A. Snetkov
Publikováno v:
Kizub, I V, Strielkov, I V, Shaifta, Y, Becker, S, Prieto-Lloret, J, Snetkov, V A, Soloviev, A I, Aaronson, P I & Ward, J P T 2013, ' Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization ', Cardiovascular Research, vol. 99, no. 3, pp. 404-411 . https://doi.org/10.1093/cvr/cvt129
Cardiovascular Research
Cardiovascular Research
Aims: To determine the role of gap junctions (GJ) in hypoxic pulmonary vasoconstriction (HPV).Methods and results: Studies were performed in rat isolated intrapulmonary arteries (IPA) mounted on a myograph, and in anesthetized rats. Hypoxia induced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533e603a2a2506ebd79607fe1fa63889
https://doi.org/10.1093/cvr/cvt129
https://doi.org/10.1093/cvr/cvt129
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e7f04018aae7e472da55e2de35207be
https://doi.org/10.1096/fasebj.29.1_supplement.1031.2
https://doi.org/10.1096/fasebj.29.1_supplement.1031.2
Autor:
Anatoly Soloviev, Irina V. Ivanova, Sergey Tishkin, S.N. Zelensky, Robert S. Moreland, Igor V. Kizub, Alexandra A. Pavlova
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 289:R755-R762
Radiation exposure increases vascular responsiveness, and this change involves endothelial damage, as well as direct effects on vascular smooth muscle. In this study, we tested the hypothesis that myofilament Ca2+sensitivity in vascular smooth muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3ae821c18405a975c37084724ab373
https://doi.org/10.1152/ajpregu.00748.2004
https://doi.org/10.1152/ajpregu.00748.2004
Publikováno v:
International journal of cardiology. 174(2)
Diabetes mellitus (DM) is a complex syndrome which leads to multiple dysfunctions including vascular disorders. Hyperglycemia is considered to be a key factor responsible for the development of diabetic vascular complications and can mediate their ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e46ebc35bfacc3a8f7ac8c7fac68e6e
https://pubmed.ncbi.nlm.nih.gov/24794552
https://pubmed.ncbi.nlm.nih.gov/24794552
Autor:
Anatoly Soloviev, Igor V. Kizub, A.V. Parshikov, Viktor Dosenko, Kateryna I. Klymenko, Tetiana Novokhatska
Publikováno v:
Journal of basic and clinical physiology and pharmacology.
Background: Endothelium and K+ channel functionality in smooth muscle cells (SMCs) regulates vascular function and is exposed to damage in diabetes. The regulatory enzyme protein kinase C (PKC) is known to play a key role in vascular tone regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa4c7c0fe75bcf875bf8d5526ee5c94
https://pubmed.ncbi.nlm.nih.gov/24468620
https://pubmed.ncbi.nlm.nih.gov/24468620