Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Igor Tvaroška"'
Autor:
Igor Tvaroška
Publikováno v:
Molecules, Vol 29, Iss 7, p 1417 (2024)
Collagens are fundamental constituents of the extracellular matrix and are the most abundant proteins in mammals. Collagens belong to the family of fibrous or fiber-forming proteins that self-assemble into fibrils that define their mechanical propert
Externí odkaz:
https://doaj.org/article/2264b325289a42598afcfcba55a83a4f
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21374-21384 (2020)
Externí odkaz:
https://doaj.org/article/33dc4c5c9d694b04aab877f33cacc473
Publikováno v:
Cells, Vol 12, Iss 2, p 324 (2023)
Integrins are heterodimeric glycoproteins crucial to the physiology and pathology of many biological functions. As adhesion molecules, they mediate immune cell trafficking, migration, and immunological synapse formation during inflammation and cancer
Externí odkaz:
https://doaj.org/article/27fa81eaf3fd438c907ff7fcb3d1d840
Autor:
Victor A. Streltsov, Sukanya Luang, Alys Peisley, Joseph N. Varghese, James R. Ketudat Cairns, Sebastien Fort, Marcel Hijnen, Igor Tvaroška, Ana Ardá, Jesús Jiménez-Barbero, Mercedes Alfonso-Prieto, Carme Rovira, Fernanda Mendoza, Laura Tiessler-Sala, José-Emilio Sánchez-Aparicio, Jaime Rodríguez-Guerra, José M. Lluch, Jean-Didier Maréchal, Laura Masgrau, Maria Hrmova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Enzyme substrates and products often diffuse too rapidly to assess the catalytic implications of these movements. Here, the authors characterise the structural basis of product and substrate diffusion for an exo-hydrolase and discover a substrate-pro
Externí odkaz:
https://doaj.org/article/393023e627f645a0b2087690681cc2f6
Publikováno v:
Molecules, Vol 25, Iss 12, p 2835 (2020)
Selectins belong to a group of adhesion molecules that fulfill an essential role in immune and inflammatory responses and tissue healing. Selectins are glycoproteins that decode the information carried by glycan structures, and non-covalent interacti
Externí odkaz:
https://doaj.org/article/3a182c2ad9f34c8ebc8103db326efde7
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004061 (2015)
The glycosylation of cell surface proteins plays a crucial role in a multitude of biological processes, such as cell adhesion and recognition. To understand the process of protein glycosylation, the reaction mechanisms of the participating enzymes ne
Externí odkaz:
https://doaj.org/article/1461800a6fcf4375b35b7bbf9aa16e19
Publikováno v:
Glycobiology
Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the globe. The spectrum of disease is broad but among hospitalized patients with COVID-19, respiratory failure from acute respiratory distress syndrome is the leading cause of mortalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cc34de1d400eb2922466820876996e
https://doi.org/10.1093/glycob/cwab021
https://doi.org/10.1093/glycob/cwab021
Autor:
Igor Tvaroška, Dalibor Trapl, Václav Mareška, Vojtěch Spiwok, Charles Oluremi Solanke, Zoran Šućur
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
Interactions between proteins and their small molecule ligands are of great importance for the process of drug design. Here we report an unbiased molecular dynamics simulation of systems containing hevein domain (HEV32) with N-acetylglucosamine mono-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d23d278cb58b5c27d868a18d8fce29
http://link.springer.com/article/10.1038/s41598-019-53815-w
http://link.springer.com/article/10.1038/s41598-019-53815-w
Publikováno v:
Physical chemistry chemical physics : PCCP. 23(41)
Tyrosine sulfation alters the biological activity of many proteins involved in different physiological and pathophysiological conditions, such as non-specific immune reaction, response to inflammation and ischemia, targeting of leukocytes and stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74215028f3f0bff54c3a813c7b0d030d
https://pubmed.ncbi.nlm.nih.gov/34647946
https://pubmed.ncbi.nlm.nih.gov/34647946
Publikováno v:
Molecules, Vol 25, Iss 2835, p 2835 (2020)
Molecules
Molecules
Selectins belong to a group of adhesion molecules that fulfill an essential role in immune and inflammatory responses and tissue healing. Selectins are glycoproteins that decode the information carried by glycan structures, and non-covalent interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e5f21de12ccbfbbde4c7019f325086
https://www.mdpi.com/1420-3049/25/12/2835
https://www.mdpi.com/1420-3049/25/12/2835