Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Igor Stern"'
Autor:
D. McCormick, F. N. Hattab, Dušan Turk, Michael J. Dixon, Reza Yaghmai, Ethlin W. Jabs, Peter Brett, Gerry Linden, Chelsee Hewitt, Pedro Bullón, Igor Stern, I. R. Wallace, Mohamed Al-Hamed, Nalin Thakker, Jacqueline James, Melanie Wong, Richard P Widmer, Stefan G. Rüdiger, Philip Sloan, Carmel Toomes, Peter H. Hoeger, James E. Briggs, Oliver Bleck, Khaled Abdul Gaffar, Gregor J. Petersilka, Liqun Zhang, Lama Awawdeh, Rebecca Howard, Maurizio Battino, Louise Southern, Andrew P. Read
Publikováno v:
Human Mutation. 23:222-228
We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon Lefevre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early,onset, severe periodontitis. Others hav
Autor:
Igor Stern, Vojko Janjić, Boris Turk, Vito Turk, John Pedersen, Marjetka Podobnik, Connie Lauritzen, Doriano Lamba, Dušan Turk, Søren W. Dahl
Publikováno v:
The EMBO Journal. 20:6570-6582
Dipeptidyl peptidase I (DPPI) or cathepsin C is the physiological activator of groups of serine proteases from immune and inflammatory cells vital for defense of an organism. The structure presented shows how an additional domain transforms the frame
Autor:
Igor Stern, Elizabeth M. A. Hirst, Angus Nash, Denise V. Dear, G.G. Dodson, Suleman Bawumia, Peter M. Bayley, Oxana Polyakova, Stephen R. Martin, Igor B. Bronstein
Publikováno v:
European biophysics journal : EBJ. 38(2)
Formation of PrP aggregates is considered to be a characteristic event in the pathogenesis of TSE diseases, accompanied by brain inflammation and neurodegeneration. Factors identified as contributing to aggregate formation are of interest as potentia
Autor:
Chelsee, Hewitt, Derek, McCormick, Gerry, Linden, Dusan, Turk, Igor, Stern, Ian, Wallace, Louise, Southern, Liqun, Zhang, Rebecca, Howard, Pedro, Bullon, Melanie, Wong, Richard, Widmer, Khaled Abdul, Gaffar, Lama, Awawdeh, Jim, Briggs, Reza, Yaghmai, Ethlin W, Jabs, Peter, Hoeger, Oliver, Bleck, Stefan G, Rüdiger, Gregor, Petersilka, Maurizio, Battino, Peter, Brett, Faiez, Hattab, Mohamed, Al-Hamed, Philip, Sloan, Carmel, Toomes, Mike, Dixon, Jacqueline, James, Andrew P, Read, Nalin, Thakker
Publikováno v:
Human mutation. 23(3)
We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon-Lefèvre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early-onset, severe periodontitis. Others ha
The crystal structure of the inhibitor NS-134 in complex with bovine cathepsin B reveals that functional groups attached to both sides of the epoxysuccinyl reactive group bind to the part of active-site cleft as predicted. The -Leu-Pro-OH side binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a58890849eac3c3c9356502a02547b6
https://doi.org/10.1042/bj20040237
https://doi.org/10.1042/bj20040237