Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Igor Shevelev"'
Autor:
Eva Csefalvay, Mikalai Lapkouski, Alena Guzanova, Ladislav Csefalvay, Tatsiana Baikova, Igor Shevelev, Vitali Bialevich, Katsiaryna Shamayeva, Pavel Janscak, Ivana Kuta Smatanova, Santosh Panjikar, Jannette Carey, Marie Weiserova, Rüdiger Ettrich
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128700 (2015)
Type I restriction-modification enzymes are multifunctional heteromeric complexes with DNA cleavage and ATP-dependent DNA translocation activities located on motor subunit HsdR. Functional coupling of DNA cleavage and translocation is a hallmark of t
Externí odkaz:
https://doaj.org/article/b86b07350fa54e1c889611e64e837d36
Autor:
Giuseppe Villani, Igor Shevelev, Eleonora Orlando, Helmut Pospiech, Juhani E Syvaoja, Enni Markkanen, Ulrich Hubscher, Nicolas Tanguy Le Gac
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93908 (2014)
DNA polymerase ε (pol ε) is believed to be the leading strand replicase in eukaryotes whereas pols λ and β are thought to be mainly involved in re-synthesis steps of DNA repair. DNA elongation by the human pol ε is halted by an abasic site (apur
Externí odkaz:
https://doaj.org/article/7b559f9d552e47b6b5eda7eab0621523
Autor:
Pavel Janscak, Sybille Schwendener, Boris Mihaljevic, Radhakrishnan Kanagaraj, Bertran Gerrits, Alessandro A. Sartori, Lu Zheng, Igor Shevelev
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 37 (8)
Nucleic Acids Research, 37 (8)
Nucleic Acids Research, 37 (8)
ISSN:1362-4962
ISSN:0301-5610
ISSN:1362-4962
ISSN:0301-5610
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fdbe40a6a906852407d6ce9d19b5c7
http://doc.rero.ch/record/302514/files/gkp147.pdf
http://doc.rero.ch/record/302514/files/gkp147.pdf
Autor:
Sujoy Chatterjee, Dylan A. Reid, Pavel Janscak, Miranda Payne, Katsuhiro Hanada, Jitka Simandlova, Igor Shevelev, Eli Rothenberg, Ian D. Hickson, Jennifer Zagelbaum, Ying Liu, Wai Kit Chu
Publikováno v:
JOURNAL OF BIOLOGICAL CHEMISTRY
Efficient repair of DNA double strand breaks and interstrand cross-links requires the homologous recombination (HR) pathway, a potentially error-free process that utilizes a homologous sequence as a repair template. A key player in HR is RAD51, the e
With the aim to identify unconventional DNA polymerases from human cells, we have set up a special assay to fractionate HeLa extracts based on the ability (i) to bypass DNA lesions, (ii) to be resistant to aphidicolin and an inhibitory antibody again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a9fa4a560247170e563883d776066a
https://ora.ox.ac.uk/objects/uuid:8df59317-7ce0-4765-a4a3-87aadb08af7a
https://ora.ox.ac.uk/objects/uuid:8df59317-7ce0-4765-a4a3-87aadb08af7a
Autor:
Nadege Gironis, Ulrich Hübscher, Giuseppe Villani, Enni Markkanen, Igor Shevelev, Juhani E. Syväoja, Sinikka Parkkinen, Nicolas Tanguy Le Gac, Helmut Pospiech, Giulia Di Cicco
Publikováno v:
Journal of Biological Chemistry. 286:32094-32104
DNA polymerase (pol) ϵ is thought to be the leading strand replicase in eukaryotes, whereas pols λ and β are believed to be mainly involved in re-synthesis steps of DNA repair. DNA elongation by the human pol ϵ is halted by an abasic site (apurin
Autor:
Giuseppe, Villani, Ulrich, Hubscher, Nadege, Gironis, Sinikka, Parkkinen, Helmut, Pospiech, Igor, Shevelev, Giulia, di Cicco, Enni, Markkanen, Juhani E, Syväoja, Nicolas, Tanguy Le Gac
Publikováno v:
The Journal of biological chemistry
DNA polymerase (pol) ϵ is thought to be the leading strand replicase in eukaryotes, whereas pols λ and β are believed to be mainly involved in re-synthesis steps of DNA repair. DNA elongation by the human pol ϵ is halted by an abasic site (apurin
Autor:
Csanád Z. Bachrati, Ulrich Hübscher, Igor Stagljar, Barbara van Loon, Ian D. Hickson, Tobias Dietschy, Igor Shevelev, Nives Selak, Joerg Hoheisel, Anette Jacob
Publikováno v:
Nucleic Acids Research
Bloom's syndrome (BS) is a cancer predisposition disorder caused by mutation of the BLM gene, encoding a member of the RecQ helicase family. Although the phenotype of BS cells is suggestive of a role for BLM in repair of stalled or damaged replicatio
Autor:
Renjie Jiao, Tobias Dietschy, Jason Piotrowski, Igor Shevelev, J A Harrigan, Fred E. Indig, Vilhelm A. Bohr, Igor Stagljar, Pavel Janscak, N Selak
Publikováno v:
Oncogene. 26:3811-3822
The Werner syndrome protein (WRN) and chromatin assembly factor 1 (CAF-1) are both involved in the maintenance of genome stability. In response to DNA-damaging signals, both of these proteins relocate to sites where DNA synthesis occurs. However, the
Publikováno v:
Nucleic Acids Research
DNA polymerase lambda (pol lambda) is a member of the X family DNA polymerases and is endowed with multiple enzymatic activities. In this work we investigated the in vitro miscoding properties of full-length, human pol lambda either in the absence or