Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Igor Saggese"'
Autor:
Igor Saggese, Elisa Bona, Max Conway, Francesco Favero, Marco Ladetto, Pietro Liò, Giovanni Manzini, Flavio Mignone
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S7, Pp 127-137 (2018)
Abstract Background De novo assembly of RNA-seq data allows the study of transcriptome in absence of a reference genome either if data is obtained from a single organism or from a mixed sample as in metatranscriptomics studies. Given the high number
Externí odkaz:
https://doaj.org/article/e652da26d3414297b14b8ff6c3154846
Autor:
Angelo Minucci, Paola Concolino, Marco Petrillo, Giovanni Scambia, Rossana Molinario, Gabriella Ferrandina, Alessandra Costella, Ettore Capoluongo, Concetta Santonocito, Giulia Canu, Giovanni Luca Scaglione, Maria De Bonis, Donatella Guarino, Flavio Mignone, Igor Saggese
Publikováno v:
Expert review of molecular diagnostics. 15(10)
Objective: Massive parallel sequencing (MPS) is the new frontier for molecular diagnostics. Twenty-four papers regarding BRCA analysis were considered for reviewing all pipelines evaluated in this field. Methods: Proposed here is an integrated MPS wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bde6f037b0ec09b3fcda24a18e5dae
https://pubmed.ncbi.nlm.nih.gov/26306726
https://pubmed.ncbi.nlm.nih.gov/26306726
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1269
RNA-Seq technology allows the rapid analysis of whole transcriptomes taking advantage of next-generation sequencing platforms. Moreover with the constant decrease of the cost of NGS analysis RNA-Seq is becoming very popular and widespread. Unfortunat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d009ad2b52e428fe34939a371cfa8cf
https://pubmed.ncbi.nlm.nih.gov/25577383
https://pubmed.ncbi.nlm.nih.gov/25577383
Publikováno v:
Methods in Molecular Biology ISBN: 9781493922901
RNA-Seq technology allows the rapid analysis of whole transcriptomes taking advantage of next-generation sequencing platforms. Moreover with the constant decrease of the cost of NGS analysis RNA-Seq is becoming very popular and widespread. Unfortunat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e47cbb0d83a08d5e6c81b8c39a929a
https://doi.org/10.1007/978-1-4939-2291-8_15
https://doi.org/10.1007/978-1-4939-2291-8_15
Autor:
Enrica Borsi, Marina Martello, Torsten Haferlach, Serena Rocchi, Igor Saggese, Carolina Terragna, Annalisa Pezzi, Flavio Mignone, Elena Zamagni, Katia Mancuso, Mauro Procacci, Lucia Pantani, Beatrice Anna Zannetti, Barbara Santacroce, Michele Cavo, Flores Dico, Giovanni Martinelli, Paola Tacchetti
Publikováno v:
ResearcherID
INTRODUCTION In newly diagnosed Multiple Myeloma (MM) patients (pts), Copy Number (CN) losses of chromosome 17p13, carrying the TP53 tumor-suppressor gene, are strong predictors of poor outcomes. On the contrary, the prognostic relevance of TP53 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea56050d8c129eed990dee4c64af818
https://doi.org/10.1182/blood.v126.23.24.24
https://doi.org/10.1182/blood.v126.23.24.24
Autor:
Torsten Haferlach, Michele Cavo, Annamaria Brioli, Flavio Mignone, Elena Zamagni, Angela Flores Dico, Marina Martello, Barbara Santacroce, Serena Rocchi, Carolina Terragna, Lucia Pantani, Mauro Procacci, Paola Tacchetti, Annalisa Pezzi, Giovanni Martinelli, Igor Saggese, Enrica Borsi
Publikováno v:
Cancer Research. 75:4248-4248
TP53 is rarely reported as being affected either by deletions or mutations in MM, even if chr17p13 copy number (CN) loss defines a samples subgroup with a particularly poor prognosis. Here we aim at retrospectively analyzing by Next Generation Sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff86c3c3b4d7f1d6d16d45bcf278347d
https://doi.org/10.1158/1538-7445.am2015-4248
https://doi.org/10.1158/1538-7445.am2015-4248
Autor:
Paola Tacchetti, Serena Rocchi, Torsten Haferlach, Gaia Ameli, Carolina Terragna, Giulia Marzocchi, Marina Martello, Annalisa Pezzi, Flavio Mignone, Giovanni Martinelli, Lucia Pantani, Angela Flores Dico, Michele Cavo, Annamaria Brioli, Katia Mancuso, Enrica Borsi, Igor Saggese, Elena Zamagni, Beatrice Anna Zannetti, Barbara Santacroce, Nicoletta Testoni
Publikováno v:
ResearcherID
Introduction. The role of TP53 tumor-suppressor gene in mediating cellular basic tumor suppressive mechanisms is crucial: its utmost importance is underscored by a 50% mutational rate among most human cancers. In MM, TP53 is rarely reported as being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bb3d451b4e2f8e9e5511689f531bc4
https://doi.org/10.1182/blood.v124.21.3400.3400
https://doi.org/10.1182/blood.v124.21.3400.3400