Zobrazeno 1 - 10
of 439
pro vyhledávání: '"Igor R. Efimov"'
Autor:
Igor R. Efimov, Jeffrey S. Flier, Robert P. George, Anna I. Krylov, Luana S. Maroja, Julia Schaletzky, Jay Tanzman, Abigail Thompson
Publikováno v:
Frontiers in Research Metrics and Analytics, Vol 9 (2024)
This commentary documents how federal funding agencies are changing the criteria by which they distribute taxpayer money intended for scientific research. Increasingly, STEMM (Science, Technology, Engineering, Mathematics, and Medicine) funding agenc
Externí odkaz:
https://doaj.org/article/17efd2f9cce843a3b77c9e2de70ff551
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Although moderate endurance exercise has been reported to improve cardiovascular health, its effects on cardiac structure and function are not fully characterized, especially with respect to sexual dimorphism. We aimed to assess the effect
Externí odkaz:
https://doaj.org/article/81be6f60bb1d4196bbe1ff2ecebfcce1
Autor:
Hanjun Ryu, Xinlong Wang, Zhaoqian Xie, Jihye Kim, Yugang Liu, Wubin Bai, Zhen Song, Joseph W. Song, Zichen Zhao, Joohee Kim, Quansan Yang, Janice Jie Xie, Rebecca Keate, Huifeng Wang, Yonggang Huang, Igor R. Efimov, Guillermo Antonio Ameer, John A. Rogers
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Myocardial infarction (MI) is one of the leading causes of death and disability. Recently developed cardiac patches provide mechanical support and additional conductive paths to promote electrical signal propagation in the MI area to synchro
Externí odkaz:
https://doaj.org/article/018e290bd73048a4b33200575ecb20e6
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a3c013d1594947069d315d2c9fe353c5
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Graphene, a 2D carbon allotrope, is revolutionizing many biomedical applications due to its unique mechanical, electrical, thermal, and optical properties. When bioengineers realized that these properties could dramatically enhance the performance of
Externí odkaz:
https://doaj.org/article/77dbc7c0ca9242bab5fafbb54ed177d1
Autor:
Anna Gams, Alejandro Nevarez, Stephanie Perkail, Aileen Venegas, Sharon A. George, Tatiana Efimova, Igor R. Efimov
Publikováno v:
Physiological Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Abnormal heart rate variability (HRV) is commonly observed in cancer patients who have undergone targeted therapy and/or surgery, yet the effects of cancer itself on cardiac function remain underexplored. Specifically, there is limited knowl
Externí odkaz:
https://doaj.org/article/64547d8cd16c4133ae398ea5eda71d25
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Simultaneous triple-parametric optical mapping of transmembrane potential, intracellular calcium, and metabolic markers for cardiac physiology shows that metabolic changes precede the effects of ischemia on cardiac electrophysiology.
Externí odkaz:
https://doaj.org/article/54385f1a69904a2fab04152fd613bd38
Autor:
Girish S. Ramlugun, Kanchan Kulkarni, Nestor Pallares-Lupon, Bastiaan J. Boukens, Igor R. Efimov, Edward J. Vigmond, Olivier Bernus, Richard D. Walton
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: High pacing frequency or irregular activity due to arrhythmia produces complex optical mapping signals and challenges for processing. The objective is to establish an automated activation time-based analytical framework applicable to op
Externí odkaz:
https://doaj.org/article/413f1a6835fd48ae8ecbdf4015b0106e
Publikováno v:
Advanced Intelligent Systems, Vol 4, Iss 8, Pp n/a-n/a (2022)
Artificial intelligence algorithms are being adopted to analyze medical data, promising faster interpretation to support doctors’ diagnostics. The next frontier is to bring these powerful algorithms to implantable medical devices. Herein, a closed
Externí odkaz:
https://doaj.org/article/d7f3b00684f04238a5a0fc097ae9e258
Autor:
Stefanie Fenske, Konstantin Hennis, René D. Rötzer, Verena F. Brox, Elvir Becirovic, Andreas Scharr, Christian Gruner, Tilman Ziegler, Verena Mehlfeld, Jaclyn Brennan, Igor R. Efimov, Audrys G. Pauža, Markus Moser, Carsten T. Wotjak, Christian Kupatt, Rasmus Gönner, Rai Zhang, Henggui Zhang, Xiangang Zong, Martin Biel, Christian Wahl-Schott
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-22 (2020)
The involvement of cAMP-dependent regulation of HCN4 in the chronotropic heart rate response is a matter of debate. Here the authors use a knockin mouse model expressing cAMP-insensitive HCN4 channels to discover an inhibitory nonfiring cell pool in
Externí odkaz:
https://doaj.org/article/6c6af2794e4b4707a82af208feb04493