Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Igor Pavlovski"'
Autor:
Sanaa Sharari, Mustapha Aouida, Idris Mohammed, Basma Haris, Ajaz Ahmad Bhat, Iman Hawari, Sabah Nisar, Igor Pavlovski, Kabir H. Biswas, Najeeb Syed, Selma Maacha, Jean-Charles Grivel, Maryam Saifaldeen, Johan Ericsson, Khalid Hussain
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized mainly by the accumulation of glycogen in the liver and kidney. It is inherited as an autosomal recessive disorder caused by mutations in the SLC2A2 g
Externí odkaz:
https://doaj.org/article/2d01c00c404341fe90e54f1b061e3e51
Autor:
Muhammad Elnaggar, Anjud Al-Mohannadi, Dhanya Kizhakayil, Christophe Michel Raynaud, Sharefa Al-Mannai, Giusy Gentilcore, Igor Pavlovski, Abbirami Sathappan, Nicholas Van Panhuys, Chiara Borsotti, Antonia Follenzi, Jean-Charles Grivel, Sara Deola
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 1-12 (2020)
Detection of factor VIII (FVIII) in cells by flow cytometry is controversial, and no monoclonal fluorescent antibody is commercially available. In this study, we optimized such an assay and successfully used it as a platform to study the functional p
Externí odkaz:
https://doaj.org/article/fce73f6aac2e416c96bb3d5602e51db0
Autor:
Sanaa Sharari, Basirudeen Kabeer, Idris Mohammed, Basma Haris, Igor Pavlovski, Iman Hawari, Ajaz Ahmad Bhat, Mohammed Toufiq, Sara Tomei, Rebecca Mathew, Najeeb Syed, Sabah Nisar, Selma Maacha, Jean-Charles Grivel, Damien Chaussabel, Johan Ericsson, Khalid Hussain
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2114 (2022)
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized by the accumulation of glycogen mainly in the liver. It is inherited in an autosomal recessive manner due to mutations in the SLC2A2 gene. SLC2A2 enco
Externí odkaz:
https://doaj.org/article/fdc507a460194407a6173afa34a196b8
Autor:
Lotfi Chouchane, Jean-Charles Grivel, Elmoubasher Abu Baker Abd Farag, Igor Pavlovski, Selma Maacha, Abbirami Sathappan, Hamad Eid Al-Romaihi, Sirin W.J. Abuaqel, Manar Mahmoud Ahmad Ata, Aouatef Ismail Chouchane, Sami Remadi, Najeeb Halabi, Arash Rafii, Mohammed H. Al-Thani, Nico Marr, Murugan Subramanian, Jingxuan Shan
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The development of prophylactic and therapeutic agents for coronavirus disease 2019 (COVID-19) is a current global health priority. Here, we investigated the presence of cross-neutralizing antibodies against severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/78735e02d86248bba861c7d04c9abd1f
Autor:
Muhammad Elnaggar, Anjud Al-Mohannadi, Waseem Hasan, Doua Abdelrahman, Mohammed J. Al-Kubaisi, Igor Pavlovski, Giusy Gentilcore, Abbirami Sathappan, Dhanya Kizhakayil, Aesha I. Ali, Suruchi Mohan, Damilola Olagunju, Chiara Cugno, Jean-Charles Grivel, Chiara Borsotti, Antonia Follenzi, Sahar I. Da’as, Sara Deola
Publikováno v:
Blood Advances. 7:697-711
Emerging gene therapy clinical trials test the correction of hemophilia A (HA) by replacing factor VIII (FVIII) in autologous hematopoietic stem cells (HSCs). Although it is known that platelets, monocyte/macrophages, and mesenchymal stromal cells ca
Autor:
Igor Pavlovski, Abbirami Sathappan, Dhanya Kizhakayil, Anjud Al-Mohannadi, Jean-Charles Grivel, Nicholas J. Van Panhuys, Sara Deola, Muhammad Elnaggar, Antonia Follenzi, Sharefa Al-Mannai, Christophe M. Raynaud, Chiara Borsotti, Giusy Gentilcore
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 1-12 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 1-12 (2020)
Detection of factor VIII (FVIII) in cells by flow cytometry is controversial, and no monoclonal fluorescent antibody is commercially available. In this study, we optimized such an assay and successfully used it as a platform to study the functional p
Autor:
Sanaa Sharari, Mustapha Aouida, Idris Mohammed, Basma Haris, Ajaz Ahmad Bhat, Iman Hawari, Sabah Nisar, Igor Pavlovski, Kabir H. Biswas, Najeeb Syed, Selma Maacha, Jean-Charles Grivel, Maryam Saifaldeen, Johan Ericsson, Khalid Hussain
Publikováno v:
Frontiers in endocrinology. 13
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized mainly by the accumulation of glycogen in the liver and kidney. It is inherited as an autosomal recessive disorder caused by mutations in the SLC2A2 g
Autor:
Igor Pavlovski, Sara Deola, Che-Ann Lachica, Elkhansa E Elgaali, Mohammed Elanbari, Giusy Gentilcore, Dhanya Kizhakayil, Chiara Cugno, Ayman Saleh, Hani Bibawi, Anjud Al-Mohannadi, Muhammad Elnaggar
Publikováno v:
Blood. 138:4236-4236
FVIII deficiency or inactivity leads to coagulation malfunction known as Hemophilia A (HA). FVIII overactivity on the contrary is commonly linked to a hypercoagulability state. In steady state, FVIII remains quiescent by forming a non-covalent comple
Autor:
Jean-Charles Grivel, Muhammad Elnaggar, Igor Pavlovski, Anjud Al-Mohannadi, Sara Deola, Chiara Cugno
Publikováno v:
Blood. 136:14-15
Introduction UM171, a novel compound with hematopoietic stem cells (HPSCs) self-renewal properties has shown great potential for expanding CD34+ HPSCs while preserving their stemness and increasing their engrafting abilities. The compound has been in