Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Igor Pavlovic"'
Autor:
Doreen Blüher, Debabrata Laha, Sabine Thieme, Alexandre Hofer, Lennart Eschen-Lippold, Antonia Masch, Gerd Balcke, Igor Pavlovic, Oliver Nagel, Antje Schonsky, Rahel Hinkelmann, Jakob Wörner, Nargis Parvin, Ralf Greiner, Stefan Weber, Alain Tissier, Mike Schutkowski, Justin Lee, Henning Jessen, Gabriel Schaaf, Ulla Bonas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Plant pathogens translocate type III effector (T3E) proteins that may be recognized by plants to trigger immunity. Here, the authors show that the Xanthomonas T3E XopH possesses a novel 1-phytase activity that is required for XopH-mediated immunity o
Externí odkaz:
https://doaj.org/article/1c1e694d16194413a790054317964bdf
Autor:
Igor Pavlovic, Divyeshsinh T. Thakor, Jessica R. Vargas, Colin J. McKinlay, Sebastian Hauke, Philipp Anstaett, Rafael C. Camuña, Laurent Bigler, Gilles Gasser, Carsten Schultz, Paul A. Wender, Henning J. Jessen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Photocaged inositol-pyrophosphates offer a tool to study cellular signalling, but their challenging synthesis has precluded any biological studies so far. Here, the authors report the synthesis and cellular delivery of a photocaged analogue, and show
Externí odkaz:
https://doaj.org/article/a6bac542d07b431a964d07a618a8a4d6
Autor:
Min Gyu Kim, Hyungyu Min, Igor Pavlovic, Rho Hyun Seong, Eun-Ha Kim, Verena B. Eisenbeis, Wooseob Kim, Seyun Kim, Amit K. Dutta, Henning J. Jessen
Publikováno v:
Proceedings of the National Academy of Sciences. 116:12952-12957
T cell-independent (TI) B cell response is critical for the early protection against pathogen invasion. The regulation and activation of Bruton’s tyrosine kinase (Btk) is known as a pivotal step of B cell antigen receptor (BCR) signaling in TI humo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215c8a06fe745037cadcec912a546fcf
https://doi.org/10.1073/pnas.1821552116
https://doi.org/10.1073/pnas.1821552116
Autor:
Sebastian Hauke, Christopher Wittwer, Tamara Bittner, Dominik Bezold, Carsten Schultz, D. Thakor, Amit K. Dutta, Henning J. Jessen, Verena B. Eisenbeis, Igor Pavlovic
Publikováno v:
Chemical Science
β-Cells respond directly to the intracellular photochemical release of caged inositol pyrophosphate isomers with modulations of oscillations in cytosolic Ca2+.
Among many cellular functions, inositol pyrophosphates (PP-InsPs) are metabolic mess
Among many cellular functions, inositol pyrophosphates (PP-InsPs) are metabolic mess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db83f7e78e5075476f97b8542c747742
http://europepmc.org/articles/PMC6419925
http://europepmc.org/articles/PMC6419925
Autor:
Henning J. Jessen, Ruta Gerasimaite, Andrea Schmidt, Alexandre Hofer, Samanta Capolicchio, Andreas Mayer, Igor Pavlovic
Publikováno v:
ACS Chemical Biology. 12:648-653
The free energy of nucleotide hydrolysis depends on phosphate concentration. Cells regulate cytosolic phosphate levels by orchestrating phosphate acquisition and storage through inositol pyrophosphates (PP-InsP) and SPX domains. Here, we report the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7366e7869ff73449d4a9488ab1bf2a1a
https://doi.org/10.1021/acschembio.7b00026
https://doi.org/10.1021/acschembio.7b00026
Publikováno v:
SYNLETT
The propagation of information inside cells is achieved in nature by small diffusible molecules. Many of these secondary messengers are highly charged species derived from myo -inositol. The diphosphoinositol polyphosphates (X-PP- myo -InsP 5 ) repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a49224ebd4b7e4a170723fdb5a9484e
Autor:
Yeon-Kyun Shin, Jooyoung Lee, Igor Pavlovic, Seung Ju Park, Jae Won Kyung, Seyun Kim, Tae-Young Yoon, Henning J. Jessen, Yong Seok Jho, Sung Hyun Kim, Tae-Sun Lee, Seulgi Lee, Yoosoo Yang, Dae-Hyuk Kweon, Byoungjae Kong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Inositol pyrophosphates such as 5-diphosphoinositol pentakisphosphate (5-IP7) are highly energetic inositol metabolites containing phosphoanhydride bonds. Although inositol pyrophosphates are known to regulate various biological events, including gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6c4e9eeb03ac839ad02516aa2a2958
https://europepmc.org/articles/PMC4961143/
https://europepmc.org/articles/PMC4961143/
Publikováno v:
Organic and Biomolecular Chemistry
Diphosphoinositol polyphosphates (inositol pyrophosphates, X-InsP7) are a family of second messengers with important roles in eukaryotic biology. Their chemical synthesis and modification remains a challenging task due to the high density of phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed450d28f0b0ce0d80f5348c1303d59c
https://pubmed.ncbi.nlm.nih.gov/26923707
https://pubmed.ncbi.nlm.nih.gov/26923707
Autor:
Ruta Gerasimaite, Michael Hothorn, Vincent Truffault, Rebekka Wild, Yves Poirier, Igor Pavlovic, Henning J. Jessen, Ji-Yul Jung, Andreas Mayer, Adolfo Saiardi, Andrea Schmidt
Publikováno v:
Science (New York N.Y.)
Science
Europe PubMed Central
Science, Vol. 352, No 6288 (2016) pp. 986-990
Science
Europe PubMed Central
Science, Vol. 352, No 6288 (2016) pp. 986-990
Phosphorus is a macronutrient taken up by cells as inorganic phosphate (P(i)). How cells sense cellular P(i) levels is poorly characterized. Here, we report that SPX domains--which are found in eukaryotic phosphate transporters, signaling proteins, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291658002de0d8045b949aa2d56a74d0
https://pubmed.ncbi.nlm.nih.gov/27080106
https://pubmed.ncbi.nlm.nih.gov/27080106
Publikováno v:
ChemInform. 45
The propagation of information inside cells is achieved in nature by small diffusible molecules. Many of these secondary messengers are highly charged species derived from myo -inositol. The diphosphoinositol polyphosphates (X-PP- myo -InsP 5 ) repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f852bd57230e90d7b07d24929497ca64
https://doi.org/10.1002/chin.201437252
https://doi.org/10.1002/chin.201437252