Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Igor Opsenica"'
Publikováno v:
Molecules, Vol 29, Iss 18, p 4308 (2024)
Our review paper evaluates the impact of plant-based products, primarily derived from plants from Serbia, on P-glycoprotein (P-gp) activity and their potential in modulating drug resistance in cancer therapy. We focus on the role and regulation of P-
Externí odkaz:
https://doaj.org/article/599099b845dd4119b482bb4cdf0fd933
Autor:
Jelena Srbljanović, Branko Bobić, Tijana Štajner, Aleksandra Uzelac, Igor Opsenica, Nataša Terzić-Jovanović, Neda Bauman, Bogdan A. Šolaja, Olgica Djurković-Djaković
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss , Pp 20-25 (2020)
Objectives: Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods: In vitro testing was performed by the lac
Externí odkaz:
https://doaj.org/article/a8083033271840b78f4f33d4570fdeaa
Autor:
IGOR OPSENICA, DEJAN OPSENICA, MILKA JADRANIN, KIRSTEN S. SMITH, WILBUR K. MILHOUS, MANOLIS STRATAKIS, BOGDAN ŠOLAJA
Publikováno v:
Journal of the Serbian Chemical Society, Vol 72, Iss 12, Pp 1181-1190 (2007)
Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure–activity relationship of this kind of antimalarials. The tetraoxanes 2–5, obtained as a cis/trans mixture, showed pronounced antimalarial activi
Externí odkaz:
https://doaj.org/article/043a0b998e2749609c8194dc9750d498
Publikováno v:
ARKIVOC, Vol 2007, Iss 8, Pp 124-135 (2006)
Externí odkaz:
https://doaj.org/article/de690dbb600045b58b25f8b988fe806c
Publikováno v:
Journal of the Serbian Chemical Society, Vol 69, Iss 11, Pp 919-922 (2004)
Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 str
Externí odkaz:
https://doaj.org/article/0df4ef50252c44d293cdf1ec13ca5903
Autor:
Tijana Štajner, Igor Opsenica, Mikloš Tot, Bogdan A. Šolaja, Jelena Srbljanović, Olgica Djurković-Djaković, Tatjana Ž. Verbić, Milica Selakovic
Publikováno v:
Journal of the Serbian Chemical Society, Vol 86, Iss 2, Pp 115-123 (2021)
Journal of the Serbian Chemical Society
Journal of the Serbian Chemical Society
Synthesis of novel aminoquinoline derivatives has been accomplished and their activity against malaria strains has been examined. The compounds showed moderate in vitro antimalarial activity against two P. falciparum strains, 3D7 (CQ susceptible clon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dea8517c031f0a41900fb336fcc1c69
https://doi.org/10.2298/jsc201225005o
https://doi.org/10.2298/jsc201225005o
Autor:
Neda Bauman, Olgica Djurković-Djaković, Aleksandra Uzelac, Tijana Štajner, Nataša Terzić-Jovanović, Jelena Srbljanović, Bogdan A. Šolaja, Branko Bobić, Igor Opsenica
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss, Pp 20-25 (2020)
Journal of Global Antimicrobial Resistance
Journal of Global Antimicrobial Resistance
Objectives Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods In vitro testing was performed by the lacta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d25e50e5e45233c8f6574713c9b02c
http://www.sciencedirect.com/science/article/pii/S2213716520302022
http://www.sciencedirect.com/science/article/pii/S2213716520302022
Publikováno v:
European Journal of Organic Chemistry
An efficient one-pot, two step method for fusing two biologically active motifs, CF3-substituted pyrazoles and isochromenes, was developed. Selective O-benzylation of CF3-substituted pyrazolones and subsequent Pd-catalyzed direct C–H arylation gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bef3270a0f7e2f881ca3aa67408aba
https://doi.org/10.1002/ejoc.202000942
https://doi.org/10.1002/ejoc.202000942
Autor:
Natasa Radakovic, Andrea Nikolić, Nataša Terzić Jovanović, Pavle Stojković, Nada Stankovic, Bogdan Šolaja, Igor Opsenica, Aleksandar Pavic
Publikováno v:
European Journal of Medicinal Chemistry
Candida albicans remains the main causal agent of candidiasis, the most common fungal infection with disturbingly high mortality rates worldwide. The limited diversity and efficacy of clinical antifungal drugs, exacerbated by emerging drug resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365be53a6c5ab9098265b4143e4e6354
http://cherry.chem.bg.ac.rs/handle/123456789/4877
http://cherry.chem.bg.ac.rs/handle/123456789/4877
Publikováno v:
European Journal of Organic Chemistry
Decarbonylation is an invaluable reaction, utilized by nature and chemists alike. In different life forms, such as prokaryotes, plants and animals, this transformation is catalyzed by aldehyde decarbonylases. In the laboratory, the transition metal-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032ce1f55b1d64d1e756121146f690bc
https://doi.org/10.1002/ejoc.202101265
https://doi.org/10.1002/ejoc.202101265