Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Igor Nepliouev"'
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26128 (2011)
Homer proteins are a family of multifaceted scaffolding proteins that participate in the organization of signaling complexes at the post-synaptic density and in a variety of tissues including striated muscle. Homer isoforms form multimers via their C
Externí odkaz:
https://doaj.org/article/bd8b38e3bc9745819b53a2704da5e801
Autor:
Francis J. Miller, Igor Nepliouev, Elizabeth R. Hauser, Tai-Qin Huang, Neil J. Freedman, Lisheng Zhang, Leigh Brian, Kamie P. Snow, Brandon M. Schickling, Jonathan A. Stiber, Jiao-Hui Wu
Publikováno v:
Cardiovasc Res
Aims The F-actin-binding protein Drebrin inhibits smooth muscle cell (SMC) migration, proliferation and pro-inflammatory signaling. Therefore, we tested the hypothesis that Drebrin constrains atherosclerosis. Methods and results SM22-Cre+/Dbnflox/flo
Autor:
Paul B. Rosenberg, Rex C. Bentley, Zhu-Shan Zhang, Neil J. Freedman, Jonathan A. Stiber, Victoria Bryson, Phillip R. Gordon-Weeks, Jiao-Hui Wu, Igor Nepliouev, Lisheng Zhang, Leigh Brian
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:984-993
Objective— Vascular smooth muscle cell (SMC) migration is regulated by cytoskeletal remodeling as well as by certain transient receptor potential (TRP) channels, nonselective cation channels that modulate calcium influx. Proper function of multiple
Autor:
Sudha K. Shenoy, Leigh Brian, Jonathan A. Stiber, Lisheng Zhang, Jiao-Hui Wu, Nathan P. Rudemiller, Virginia Wertman, Neil J. Freedman, Tai-Qin Huang, Francis J. Miller, Timothy J. McMahon, Zhu-Shan Zhang, Steven D. Crowley, Igor Nepliouev
Publikováno v:
Cardiovascular research. 114(13)
AIMS: The actin-binding protein Drebrin is up-regulated in response to arterial injury and reduces smooth muscle cell (SMC) migration and proliferation through its interaction with the actin cytoskeleton. We, therefore, tested the hypothesis that SMC
Autor:
Paul B. Rosenberg, Sai-Hong Ignatius Ou, Igor Nepliouev, Jonathan A. Stiber, Hengtao Zhang, Zhu-Shan Zhang, Adam S. Barnett, Tai-Qin Huang
Publikováno v:
Cardio-Oncology. 3
Sinus bradycardia is frequently observed in patients treated with crizotinib, a receptor tyrosine kinase inhibitor used for the treatment of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC). We investigated whether crizo
Autor:
Geoffrey S. Pitt, Jong J. Kim, Jonathan A. Stiber, W. J. Lederer, Nenad Bursac, Igor Nepliouev, Tianyu Li, Elizabeth A. Finch, Paul B. Rosenberg, Albert Y. Sun, Hengtao Zhang, Guiling Zhao, Victoria Graham
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Cardiac pacemaking is governed by specialized cardiomyocytes located in the sinoatrial node (SAN). SAN cells (SANCs) integrate voltage-gated currents from channels on the membrane surface (membrane clock) with rhythmic Ca(2+) release from internal Ca
Publikováno v:
Proceedings of the National Academy of Sciences. 94:6826-6830
The infectious reovirus RNA system was used to construct a mutant with two temperature-sensitive (ts) lesions in genome segments M2 and S2, respectively. The double mutant is about 300 times more ts than either of its parents, which are about 1,500 a