Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Igor M. Rakov"'
Publikováno v:
Rapid Communications in Mass Spectrometry. 22:639-646
A rapid method for quantitative chiral analysis of phthaloylglutamic acid and its dimethyl ester by Cook's kinetic method is demonstrated using electrospray ionization (ESI) and matrix-assisted laser desorption techniques. Transition-metal-bound comp
Autor:
Dennis R. Feller, Duane D. Miller, Igor M. Rakov, Joseph E. De Los Angeles, LeNe’Sheya Y. Boyd, Ratna C. Mehta, Victor I. Nikulin
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:1684-1697
Trimetoquinol (TMQ, 1 ) is a potent non-selective β-adrenoceptor (β-AR) agonist possessing a tetrahydroisoquinoline (THI) structure. The binding site for 1-trimethoxybenzyl group of 1 , which distinguishes it from classical catecholamines, is unkno
Nonsteroidal tissue selective androgen receptor modulators: a promising class of clinical candidates
Autor:
Duane D. Miller, Renukadevi Patil, Igor M. Rakov, Dong Jin Hwang, Michael L. Mohler, Vipin A. Nair
Publikováno v:
Expert Opinion on Therapeutic Patents. 15:1565-1585
The androgen receptor (AR) is a nuclear hormone receptor that, upon binding to testosterone, dihydrotestosterone (DHT) and other endogenous androgens, supports the development, growth and maintenance of masculine features through activation of anabol
Autor:
Kenneth W. Henderson, Mark R. J. Elsegood, John F. Allan, Igor M. Rakov, Paul H. Moran, William Clegg, Arlene E. McKeown
Publikováno v:
Journal of Organometallic Chemistry. 602:15-23
Reaction of Me3Al with a series of aromatic ketones results in the precipitation of either dimethylaluminium enolates or alkoxides. In situ 1H-NMR spectroscopic studies of the reaction between Me3Al and acetophenone reveal a complex mixture of produc
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 149:75-83
The methyl ester of 3-azidotetrafluoropropionic acid, N3-CF2CF2COOMe oxidatively fluorinates P(III), Sb(III) and Te(II) compounds to form the corresponding difluorides in good yield.
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 419:201-204
The reactivity of P(III) compounds towards fluorination by Ph 3 BiF 2 was studied from the viewpoint of frontier molecular orbitals theory. The highest occupied molecular orbital (HOMO) energies of phosphites and amidophosphites were calculated. A qu
Publikováno v:
Tetrahedron Letters. 37:4051-4054
Terminal acetylenes readily undergo phenylation by Ph3BiF2 in the presence of catalytic amounts of CuCl affording phenyl substituted acetylenes.
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 92:225-229
Triphenylbismuth difluoride, Ph3BiF2, is a mild source for the oxidative fluorination of organic compounds of P(III), Sb(III) and Se(II), bearing electron donating, non-bulky substituents.
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 57:m387-m389
The title compound, [{Al(CH3)2}2(C12H18O)2], formed by the Me3Al-mediated alkylation of mesitylaldehyde, is dimeric in the solid state, with a central Al2O2 planar ring core residing on an inversion centre.
Publikováno v:
ChemInform. 30
Hexafluoropropene oxide (HFPO) is shown to be a good reagent for the nucleophilic formation of the element–fluorine bond in organoelement compounds. Fluorides of Bi, Sb, Se, Te and I were prepared from appropriate oxygen compounds