Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Igor M. Neelov"'
Autor:
Valeriy V. Bezrodnyi, Sofia E. Mikhtaniuk, Oleg V. Shavykin, Nadezhda N. Sheveleva, Denis A. Markelov, Igor M. Neelov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 691 (2024)
The development of new nanocontainers for hydrophobic drugs is one of the most important tasks of drug delivery. Dendrimers with hydrophobic interiors and soluble terminal groups have already been used as drug carriers. However, the most convenient c
Externí odkaz:
https://doaj.org/article/24933b25914a450f86bcb3ead90d8977
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3063 (2023)
The molecular dynamics method was used to study the structure and properties of dendrigrafts of the first and second generations in methanol–water mixtures with various volume fractions of methanol. At a small volume fraction of methanol, the size
Externí odkaz:
https://doaj.org/article/ee4b4c15450c42b1a97c821630b539a4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2763 (2023)
The design of nanoassemblies can be conveniently achieved by tuning the strength of the hydrophobic interactions of block copolymers in selective solvents. These block copolymer micelles form supramolecular aggregates, which have attracted great atte
Externí odkaz:
https://doaj.org/article/a738f91151784aa3b334164b426e69f4
Autor:
Oleg V. Shavykin, Sofia E. Mikhtaniuk, Emil I. Fatullaev, Igor M. Neelov, Frans A. M. Leermakers, Mariano E. Brito, Christian Holm, Oleg V. Borisov, Anatoly A. Darinskii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2078 (2023)
In this article, we used the numerical self-consistent field method of Scheutjens–Fleer to study the micellization of hybrid molecules consisting of one polylysine dendron with charged end groups and several linear hydrophobic tails attached to its
Externí odkaz:
https://doaj.org/article/aaa9da1109284156a15efe01b2277900
Autor:
Nadezhda N. Sheveleva, Irina I. Tarasenko, Mikhail A. Vovk, Mariya E. Mikhailova, Igor M. Neelov, Denis A. Markelov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 949 (2023)
In this paper we study two lysine-based peptide dendrimers with Lys-His-Arg and Lys-Arg-His repeating units and terminal lysine groups. Combination of His and Arg properties in a dendrimer could be important for biomedical applications, especially fo
Externí odkaz:
https://doaj.org/article/7f02c3ced3274a948f0f2fcc6c0cfac2
Autor:
Valeriy V. Bezrodnyi, Sofia E. Mikhtaniuk, Oleg V. Shavykin, Igor M. Neelov, Nadezhda N. Sheveleva, Denis A. Markelov
Publikováno v:
Molecules, Vol 26, Iss 21, p 6552 (2021)
Novel peptide dendrimer with Lys-2His repeating units was recently synthesized, studied by NMR (Molecules, 2019, 24, 2481) and tested as a nanocontainer for siRNA delivery (Int. J. Mol. Sci., 2020, 21, 3138). Histidine amino acid residues were insert
Externí odkaz:
https://doaj.org/article/d29294a8a720488abdfb868356fcb48f
Autor:
Valeriy V. Bezrodnyi, Oleg V. Shavykin, Sofia E. Mikhtaniuk, Igor M. Neelov, Nadezhda N. Sheveleva, Denis A. Markelov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9749 (2020)
New peptide dendrimer with Lys-2Arg repeating units was recently studied experimentally by NMR (RSC Advances, 2019, 9, 18018) and tested as gene carrier successfully (Int. J. Mol. Sci., 2020, 21, 3138). The unusual slowing down of the orientational m
Externí odkaz:
https://doaj.org/article/bc335596fc6f45fd94f37852ecfefef2
Autor:
Sofia E. Mikhtaniuk, Valeriy V. Bezrodnyi, Oleg V. Shavykin, Igor M. Neelov, Nadezhda N. Sheveleva, Anastasia V. Penkova, Denis A. Markelov
Publikováno v:
Polymers, Vol 12, Iss 8, p 1657 (2020)
In this paper, we perform computer simulation of two lysine-based dendrimers with Lys-2Lys and Lys-2Gly repeating units. These dendrimers were recently studied experimentally by NMR (Sci. Reports, 2018, 8, 8916) and tested as carriers for gene delive
Externí odkaz:
https://doaj.org/article/01a8e8f0110046cda161767b47fe90ed
Autor:
Boris M. Okrugin, Ralf P. Richter, Frans A. M. Leermakers, Igor M. Neelov, Ekaterina B. Zhulina, Oleg V. Borisov
Publikováno v:
Polymers, Vol 12, Iss 4, p 898 (2020)
End-grafting of polyelectrolyte chains to conducting substrates offers an opportunity to fabricate electro-responsive surfaces capable of changing their physical/chemical properties (adhesion, wettability) in response to applied electrical voltage. W
Externí odkaz:
https://doaj.org/article/6e831f7333d448ada94fd799d4b09f7e
Autor:
Michał Gorzkiewicz, Olga Kopeć, Anna Janaszewska, Małgorzata Konopka, Elżbieta Pędziwiatr-Werbicka, Irina I. Tarasenko, Valeriy V. Bezrodnyi, Igor M. Neelov, Barbara Klajnert-Maculewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3138 (2020)
The disruption of the cellular pathways of protein biosynthesis through the mechanism of RNA interference has been recognized as a tool of great diagnostic and therapeutic significance. However, in order to fully exploit the potential of this phenome
Externí odkaz:
https://doaj.org/article/dba0a9b8913f4b50a7d914f02ee1e990