Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Igor M, Sauer"'
Autor:
Nathanael Raschzok, Simon Moosburner, Moritz Blank, Felix Krenzien, Georg Lurje, Wenzel Schöning, Igor M. Sauer, Johann Pratschke, Dominik P. Modest, Annika Kurreck
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Multimodal two-stage hepatectomy (mTSH) is used in patients with bilobar colorectal liver metastases (CRLM) that cannot be treated with one surgical procedure due to insufficient future liver remnant. Interval chemotherapy has bee
Externí odkaz:
https://doaj.org/article/9c2f0350e7de4f1788ca33b29e4f6797
Autor:
Louise Wutsdorff, Julienne Mougnekabol, Peter Tang, Anja Reutzel-Selke, Igor M. Sauer, Nils Haep
Publikováno v:
Livers, Vol 4, Iss 3, Pp 406-419 (2024)
Cell-death-inducing DNA fragmentation factor-alpha (DFFA)-like effector b (CIDEB) was first identified as an apoptosis-inducing protein. Further research revealed a pivotal role in lipid metabolism, regulating very-low-density lipoprotein (VLDL), lip
Externí odkaz:
https://doaj.org/article/f12feb41a2b449f9b5171a9036c71ded
Autor:
Lisa-Marie Skrip, Simon Moosburner, Peter Tang, Jing Guo, Steffen Görner, Heiko Tzschätzsch, Kristin Brüggemann, Kilian Alexander Walter, Clarissa Hosse, Uli Fehrenbach, Alexander Arnold, Dominik Modest, Felix Krenzien, Wenzel Schöning, Thomas Malinka, Johann Pratschke, Björn Papke, Josef A. Käs, Ingolf Sack, Igor M. Sauer, Karl H. Hillebrandt
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Colorectal cancer is the third most common tumour entity in the world and up to 50% of the patients develop liver metastases (CRLM) within five years. To improve and personalize therapeutic strategies, new diagnostic tools are urg
Externí odkaz:
https://doaj.org/article/4d8a063d200f4829a702332450f30823
Autor:
Isis Lozzi, Alexander Arnold, Matthias Barone, Juliette Claire Johnson, Bruno V Sinn, Johannes Eschrich, Pimrapat Gebert, Ruonan Wang, Mengwen Hu, Linda Feldbrügge, Anja Schirmeier, Anja Reutzel-Selke, Thomas Malinka, Felix Krenzien, Wenzel Schöning, Dominik P Modest, Johann Pratschke, Igor M Sauer, Matthäus Felsenstein
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Background Intrahepatic cholangiocarcinoma (ICC) is a disease with poor prognosis and limited therapeutic options. We investigated the tumor immune microenvironment (TIME) to identify predictors of disease outcome and to explore targets for therapeut
Externí odkaz:
https://doaj.org/article/e0446c6ce3f8424696faa2dce6d8a997
Autor:
Peter Tang, Eriselda Keshi, Silvana Wilken, Louise Wutsdorff, Julienne Mougnekabol, Johann Pratschke, Igor M. Sauer, Nils Haep
Publikováno v:
Stem Cell Research, Vol 80, Iss , Pp 103516- (2024)
Metabolic dysfunction-associated fatty liver disease (MAFLD), the leading cause of end-stage liver disease in developed countries, is expected to increase over the next decade. Characterized by hepatic steatosis, MAFLD is commonly studied in animal m
Externí odkaz:
https://doaj.org/article/bfcc31c69183491daa51b0deb0de3767
Autor:
Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher, Benjamin Struecker
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Background The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality. Understanding the co
Externí odkaz:
https://doaj.org/article/184b7542c395420292ac63157f983099
Autor:
Nathanael Raschzok, Simon Moosburner, Moritz Blank, Felix Krenzien, Georg Lurje, Wenzel Schöning, Igor M. Sauer, Johann Pratschke, Dominik P. Modest, Annika Kurreck
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/3446e2ac461442b9a31dd83956360f26
Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
Autor:
Muhammad Imtiaz Ashraf, Joerg Mengwasser, Anja Reutzel-Selke, Dietrich Polenz, Kirsten Führer, Steffen Lippert, Peter Tang, Edward Michaelis, Rusan Catar, Johann Pratschke, Christian Witzel, Igor M. Sauer, Stefan G. Tullius, Barbara Kern
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute cellular rejection remains a significant obstacle affecting successful outcomes of organ transplantation including vascularized composite tissue allografts (VCA). Donor antigen presenting cells (APCs), particularly dendritic cells (DCs), orches
Externí odkaz:
https://doaj.org/article/cb6068b1a8d7413cbf4de018498537e7
Autor:
Nathalie N Roschke, Karl H Hillebrandt, Dietrich Polenz, Oliver Klein, Joseph M G V Gassner, Johann Pratschke, Felix Krenzien, Igor M Sauer, Nathanael Raschzok, Simon Moosburner
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297497 (2024)
BackgroundConsidering the expected increase in the elderly population and the growing emphasis on aging-related biomedical research, the demand for aged laboratory animals has surged, challenging established husbandry practices. Our objective was to
Externí odkaz:
https://doaj.org/article/736b7f9208884f70b0a0e0e156d05e83
Autor:
Simon Moosburner, MD, Chiara Kettler, Karl H. Hillebrandt, MD, Moritz Blank, Hannes Freitag, Sebastian Knitter, MD, Felix Krenzien, MD, Nora Nevermann, MD, Igor M. Sauer, MD, Dominik P. Modest, MD, Georg Lurje, MD, Robert Öllinger, MD, Wenzel Schöning, MD, Jens Werner, MD, Maximilian Schmeding, MD, Johann Pratschke, MD, Nathanael Raschzok, MD, members of StuDoQ|Liver of Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie/StuDoQ
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 4, p e350 (2023)
Objective:. To compare the outcome of minimally invasive liver surgery (MILS) to open liver surgery (OLS) for resection of colorectal liver metastases (CRLM) on a nationwide level. Background:. Colorectal cancer is the third most common malignancy wo
Externí odkaz:
https://doaj.org/article/568b6fc3243c4c029b550d82e9619bf9