Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Igor L. Chernyavsky"'
Autor:
Qi Zhou, Kerstin Schirrmann, Eleanor Doman, Qi Chen, Naval Singh, P. Ravi Selvaganapathy, Miguel O. Bernabeu, Oliver E. Jensen, Anne Juel, Igor L. Chernyavsky, Timm Krüger
Publikováno v:
Zhou, Q, Schirrmann, K, Doman, E, Chen, Q, Singh, N, Selvaganapathy, P R, Bernabeu, M O, Jensen, O E, Juel, A, Chernyavsky, I L & Krüger, T 2022, ' Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media ', Interface Focus, vol. 12, no. 6, 20220037 . https://doi.org/10.1098/rsfs.2022.0037
The dynamics of blood flow in the smallest vessels and passages of the human body, where the cellular character of blood becomes prominent, plays a dominant role in the transport and exchange of solutes. Recent studies have revealed that the micro-ha
Publikováno v:
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 478
We investigate the transport of a solute past isolated sinks in a bounded domain when advection is dominant over diffusion, evaluating the effectiveness of homogenization approximations when sinks are distributed uniformly randomly in space. Correcti
Publikováno v:
Physics Today. 76:26
The flow and transport of solute molecules in the intricate structure of the placenta make the organ a fetal life-support system.
Autor:
Philip Pearce, Paul Brownbill, Jiří Janáček, Marie Jirkovská, Lucie Kubínová, Igor L Chernyavsky, Oliver E Jensen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165369 (2016)
During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous a
Externí odkaz:
https://doaj.org/article/5a37cc9e245d4b71be0e5d8dc4e7a4bc
Autor:
Igor L. Chernyavsky, Oliver E. Jensen
Publikováno v:
Annual Review of Fluid Mechanics. 51:25-47
The placenta is a multifunctional organ that exchanges blood gases and nutrients between a mother and her developing fetus. In humans, fetal blood flows through intricate networks of vessels confined within villous trees, the branches of which are ba
Autor:
Igor L Chernyavsky, Huguette Croisier, Lloyd A C Chapman, Laura S Kimpton, Jonathan E Hiorns, Bindi S Brook, Oliver E Jensen, Charlotte K Billington, Ian P Hall, Simon R Johnson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90162 (2014)
Despite a large amount of in vitro data, the dynamics of airway smooth muscle (ASM) mass increase in the airways of patients with asthma is not well understood. Here, we present a novel mathematical model that describes qualitatively the growth dynam
Externí odkaz:
https://doaj.org/article/7dbb3a86909349c9b4fd145bf4f2df73
Autor:
Michele C. Darrow, Oliver N. King, Igor L. Chernyavsky, Edward D. Johnstone, Yasuaki Tokudome, Gowsihan Poologasundarampillai, William M Tun, Helen Bischof, Paul Brownbill, Rohan M. Lewis, Gareth A. Nye, Mark Basham
Publikováno v:
Journal of the Royal Society Interface
Multi-scale structural assessment of biological soft tissue is challenging but essential to gain insight into structure-function relationships of tissue/organ. Using the human placenta as an example, this study brings together sophisticated sample pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e556571cf96480c8d40d80d34b4e90
https://doi.org/10.1101/2020.12.07.411462
https://doi.org/10.1101/2020.12.07.411462
Autor:
Ruth Saunders, Richard J. Russell, Christopher E. Brightling, Igor L. Chernyavsky, Bindi S. Brook
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 61:660-661
Publikováno v:
Interface Focus
Erlich, A, Nye, G A, Brownbill, P, Jensen, O E & Chernyavsky, I L 2019, ' Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks ', Interface Focus . https://doi.org/10.1098/rsfs.2019.0021
Erlich, A, Nye, G A, Brownbill, P, Jensen, O E & Chernyavsky, I L 2019, ' Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks ', Interface Focus . https://doi.org/10.1098/rsfs.2019.0021
The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure of villi in
Autor:
Igor L. Chernyavsky, Alexander Erlich, Oliver E. Jensen, Philip L. Pearce, Romina Plitman Mayo
Publikováno v:
Erlich, A, Pearce, P, Plitman Mayo, R, Jensen, O & Chernyavsky, I 2019, ' Physical and geometric determinants of transport in feto-placental microvascular networks ', Science Advances, vol. 5, no. 4, eaav6326 . https://doi.org/10.1126/sciadv.aav6326
Science Advances
Science Advances
Key geometric factors that determine nutrient transport in the functional exchange unit of the human placenta are identified.
Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the pri
Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb1c42a88dc9a03d058d5500477f1a5
https://doi.org/10.1126/sciadv.aav6326
https://doi.org/10.1126/sciadv.aav6326