Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Igor Kitanovic"'
Autor:
Igor Kitanovic, Stefan Wölfl, Franziska Schramm, Kristin Löbner, Jan Hoyer, Ines Neundorf, Robert Rennert
Publikováno v:
Pharmaceuticals, Vol 2, Iss 2, Pp 49-65 (2009)
Cell-penetrating peptides (CPP) have become a widely used tool for efficient cargo delivery into cells. However, one limiting fact is their uptake by endocytosis causing the enclosure of the CPP-cargo construct within endosomes. One often used method
Externí odkaz:
https://doaj.org/article/84f9c6b2c1d14c87bafb3ab1c07b0794
Autor:
Hamed Alborzinia, Suzan Can, Pavlo Holenya, Catharina Scholl, Elke Lederer, Igor Kitanovic, Stefan Wölfl
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19714 (2011)
Since the discovery of cisplatin more than 40 years ago and its clinical introduction in the 1970s an enormous amount of research has gone into elucidating the mechanism of action of cisplatin on tumor cells. With a novel cell biosensor chip system a
Externí odkaz:
https://doaj.org/article/496faa8e06dc40e1b47cdef474b3182c
Autor:
Felix Bonowski, Ana Kitanovic, Peter Ruoff, Jinda Holzwarth, Igor Kitanovic, Van Ngoc Bui, Elke Lederer, Stefan Wölfl
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10727 (2010)
Stability and biological activity of proteins is highly dependent on their physicochemical environment. The development of realistic models of biological systems necessitates quantitative information on the response to changes of external conditions
Externí odkaz:
https://doaj.org/article/1ebf324b09854937a1b37b079cf68de7
Autor:
Igor Kitanovic, Stefan Wölfl, Ingo Ott, Andreas Meyer, Yvonne Geldmacher, Christine Kasper, William S. Sheldrick, Suzan Can, Hamed Alborzinia, Melanie Oleszak
Publikováno v:
Journal of Inorganic Biochemistry. 106:126-133
The cytostatic properties and cellular effects of novel diene-ruthenium(II) complexes of the types OC-6-13-[RuCl(2)(pp)(cod)] 1-5 (pp=2,2'-bipyridyl (bpy), phen=1,10-phenanthroline (phen), 5,6-dimethylphenanthroline (5,6-Me2phen), dipyrido[3,2-d:2',3
Publikováno v:
PROTEOMICS. 11:2129-2133
Commonly used colorimetric detection applied to protein microarrays with enzymatic signal amplification leads to non-linear signal production upon increase in analyte concentration, thereby considerably limiting the range and accuracy of quantitative
Autor:
Igor Kitanovic, Stefan Wölfl, Ronald Gust, Aram Prokop, Soo-Young Lee, Günter Henze, Annegret Hille, Patrick Jesse
Publikováno v:
Leukemia Research. 35:387-393
We demonstrate the cytotoxic potential of the Schiff base iron complex [Fe III (salophene)Cl] in vitro and ex vivo and illustrate its ability to overcome multiple drug resistance in vincristine and daunorubicine resistant leukemic cells (Nalm-6). Tre
Autor:
Andreas Meyer, Hamed Alborzinia, Ruth Bieda, Stefan Wölfl, William S. Sheldrick, Ingo Ott, Igor Kitanovic
Publikováno v:
BioMetals. 24:645-661
The cytostatic properties of novel rhodium(III) thiacrown ether complexes [RhCl(LL)([9]aneS(3))](n+) with either aromatic κ(2)N ligands (n = 2) or anionic chelate ligands (n = 1) have been investigated for the human cancer cell lines HT-29 and MCF-7
Autor:
Robert Rennert, Kristin Löbner, Igor Kitanovic, Ines Neundorf, Jan Hoyer, Stefan Wölfl, Franziska Schramm
Publikováno v:
Pharmaceuticals; Volume 2; Issue 2; Pages: 49-65
Pharmaceuticals
Pharmaceuticals, Vol 2, Iss 2, Pp 49-65 (2009)
Pharmaceuticals
Pharmaceuticals, Vol 2, Iss 2, Pp 49-65 (2009)
Cell-penetrating peptides (CPP) have become a widely used tool for efficient cargo delivery into cells. However, one limiting fact is their uptake by endocytosis causing the enclosure of the CPP-cargo construct within endosomes. One often used method
Autor:
Jinda Holzwarth, Ana Kitanovic, Ngoc Van Bui, Stefan Wölfl, Jean Marie François, Thomas Walther, Felix Bonowski, Marie Odile Loret, Igor Kitanovic
Publikováno v:
FEMS Yeast Research. 9:535-551
Maintenance and adaptation of energy metabolism could play an important role in the cellular ability to respond to DNA damage. A large number of studies suggest that the sensitivity of cells to oxidants and oxidative stress depends on the activity of
Autor:
William S. Sheldrick, Caroline Bischof, Ulrich Schatzschneider, Stefan Wölfl, Annegret Hille, Hamed Alborzinia, Ingo Ott, Ana Kitanovic, Sven Schäfer, Igor Kitanovic, Ronald Gust, Elke Lederer, Nils Metzler-Nolte
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 14:711-725
We developed N,N'-bis(salicylidene)-1,2-phenylenediamine (salophene, 1) as a chelating agent for metal ions such as Mn(II/III), Fe(II/III), Co(II), Ni(II), Cu(II), and Zn(II). The resulting complexes, from which owing to the carrier ligand a selectiv