Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Igor E, Makarenko"'
Autor:
Alexander Y. Mayorov, Roman V. Drai, Tatiana L. Karonova, Olga I. Avdeeva, Igor E. Makarenko, Ekaterina O. Koksharova, Ekaterina Е. Mishina, Yulia А. Sevastyanova, Olena V. Afonkina
Publikováno v:
Сахарный диабет, Vol 23, Iss 4, Pp 304-315 (2020)
Background: Prevention of the development of micro-and macrovascular complications in patients with diabetes melli-tus (DM) encouraged the search for insulin analogues that allow imitating, as close as possible, a normal physiological insulin secreti
Externí odkaz:
https://doaj.org/article/b3a6691ae08b4a68a1b2aa25127806f7
Autor:
Denis V Kurkin, Dmitry A Bakulin, Evgeny I Morkovin, Anna V Kalatanova, Igor E Makarenko, Artem R Dorotenko, Nikolay S Kovalev, Marina A Dubrovina, Dmitry V Verkholyak, Elizaveta E Abrosimova, Alexey V Smirnov, Maksim V Shmidt, Ivan N Tyurenkov
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254493 (2021)
This study was the first to compare the neuroprotective activity of Cerebrolysin®, Actovegin® and Cortexin® in rodent models of acute and chronic brain ischemia. The neuroprotective action was evaluated in animals with acute (middle cerebral arter
Externí odkaz:
https://doaj.org/article/e345af691eb64e8cace1bedfb00ef977
Autor:
Alexander Y. Mayorov, Ekaterina O. Koksharova, Ekaterina E. Mishina, Roman V. Drai, Olga I. Avdeeva, Igor E. Makarenko
Publikováno v:
Сахарный диабет, Vol 21, Iss 6, Pp 462-471 (2018)
Background: Modern medicine requires use of effective antidiabetic drugs that can imitate the natural profile of insulin in the body of patients with diabetes mellitus. Examples of such preparations include biphasic insulin lispro, which is a mixture
Externí odkaz:
https://doaj.org/article/07ba711824f147319dd77765ca8b606e
Autor:
Alina Y. Babenko, Anna A. Mosikian, Igor E. Makarenko, Victoriya V. Leusheva, Evgeny V. Shlyakhto
Publikováno v:
Сахарный диабет, Vol 21, Iss 4, Pp 241-254 (2018)
Background: Dipeptidyl-peptidase-4 inhibitors (iDPP-4) are pathogenically targeted drugs for diabetes mellitus type 2 (T2DM). Evogliptin is a new member of iDPP-4 class. The drug has the longest half-elimination period among the class, and its effica
Externí odkaz:
https://doaj.org/article/27831b07e20444e996454c54095fada3
Autor:
Roman V Drai, Alexander Y Mayorov, Tatiana L Karonova, Tatiana M Parfenova, Igor E Makarenko, Maxim A Magruk, Diana N Alpenidze, Vladislav V Kovalik, Bella R Zinnatulina, Irina V Grigorjeva, Alena T Andreeva
Publikováno v:
Journal of Comparative Effectiveness Research. 11:1337-1347
Aim: To evaluate the safety and efficacy of insulin Aspart-Mix biosimilar candidate GP40081 (GP-Asp30) compared with NovoMix ® 30 (NN-Asp30). Materials & methods: In a randomized open-label, active-controlled, 26-week non-inferiority clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315c627c7d0d03446349dbf5c0c54355
https://doi.org/10.2217/cer-2021-0232
https://doi.org/10.2217/cer-2021-0232
Autor:
Victoria S, Kulesh, Roman V, Drai, Bella R, Zinnatulina, Igor E, Makarenko, Fedor G, Pilyus, Alexander L, Khokhlov
Publikováno v:
The Journal of Clinical Pharmacology. 62:1086-1093
This study includes modeling and simulation of insulin aspart pharmacokinetics (PK). The authors used PK data of biosimilar insulins-insulin aspart and biphasic insulin aspart 30/70-to develop a predictive population PK model for the insulins. The mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23ffbb5f9e93ad0a1253879cfb341b4
https://doi.org/10.1002/jcph.2049
https://doi.org/10.1002/jcph.2049
Autor:
Roman V. Drai, Tatiana L. Karonova, Alexander Y. Mayorov, Igor E. Makarenko, Artem R. Dorotenko, Viktoria S. Kulesh, Vladislav V. Kovalik, Alena T. Andreeva
Publikováno v:
Clinical Pharmacology in Drug Development. 11:922-929
Insulin aspart is a short-acting insulin analogue that is used to control postprandial glycemia levels in diabetic patients. The aim of this clinical trial was to compare the pharmacokinetics and pharmacodynamics of GP40071 (GP-Asp) and NovoRapid Pen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a2cf162d43c563f813005fb70e7c84
https://doi.org/10.1002/cpdd.1084
https://doi.org/10.1002/cpdd.1084
Autor:
Olga N. Pozharitskaya, Alexander N. Shikov, Into Laakso, Tuulikki Seppänen-Laakso, Igor E. Makarenko, Natalya M. Faustova, Marina N. Makarova, Valery G. Makarov
Publikováno v:
Journal of Functional Foods, Vol 17, Iss , Pp 227-234 (2015)
The gonads of sea urchins have been consumed by humans since ancient times. However, relatively little information is available on their biological activity. In the present study, we have consecutively extracted gonads of green sea urchins Strongyloc
Externí odkaz:
https://doaj.org/article/fb609024821f499eb9161905551185f3
Autor:
Aleksandr V. Petrov, Bella R. Zinnatulina, Roman V. Drai, Tatiana L. Karonova, Ekaterina O. Koksharova, Artem R. Dorotenko, Igor E. Makarenko
Publikováno v:
Clinical pharmacology in drug developmentReferences. 11(12)
This paper presents an analysis of data from a comparative study of biosimilarity in terms of pharmacokinetics and pharmacodynamics in healthy volunteers using a hyperinsulinemic euglycemic clamp for reference and test biphasic insulin aspart 30 (BIA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562726cb820ea76fe27bf63bd0d52a08
https://pubmed.ncbi.nlm.nih.gov/35980375
https://pubmed.ncbi.nlm.nih.gov/35980375
Autor:
Maria V Verbovaya, Ivan S Lunev, Anna A Mosikian, Bella R Zinnatulina, Alexandr Y Mayorov, Diana N Alpenidze, Igor E. Makarenko, Roman V. Drai, Alexander L Khokhlov, Valeria L Orlova
Publikováno v:
Journal of Comparative Effectiveness Research. 10:55-66
Aim: To compare safety (immunogenicity) and efficacy of a biosimilar insulin GP-Lis25 and a reference insulin Ly-Lis25 (Humalog Mix 25) in Type 2 diabetes mellitus (T2D) patients. Materials & methods: This randomized open-label, 26-week clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906c65ee64499c9830107b39960acf29
https://doi.org/10.2217/cer-2020-0064
https://doi.org/10.2217/cer-2020-0064