Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Igor D. Vilfan"'
Autor:
David Dulin, Igor D. Vilfan, Bojk A. Berghuis, Susanne Hage, Dennis H. Bamford, Minna M. Poranen, Martin Depken, Nynke H. Dekker
Publikováno v:
Cell Reports, Vol 10, Iss 6, Pp 983-992 (2015)
RNA viruses have specific mutation rates that balance the conflicting needs of an evolutionary response to host antiviral defenses and avoidance of the error catastrophe. While most mutations are known to originate in replication errors, difficulties
Externí odkaz:
https://doaj.org/article/a6b664ecbfa3478b90d40c81b2055d22
Autor:
Galit Meshulam-Simon, David K. Hong, Michael Rosen, Sanjeev Balakrishnan, Gregory D. Wall, Igor D. Vilfan, Fred Christians, Samuel Yang, Judith C. Wilber, James V. Quinn, Shivkumar Venkatasubrahmanyam, Desiree Hollemon, Lily Blair, Mickey Kertesz, Timothy A. Blauwkamp, Trupti Kawli, Martin S. Lindner, Simone A. Thair, Huijse Liza, Marla Lay Vaughn, Anita Cheung, Zoë N. Rogers, Sivan Bercovici
Publikováno v:
Nature Microbiology. 4:663-674
Thousands of pathogens are known to infect humans, but only a fraction are readily identifiable using current diagnostic methods. Microbial cell-free DNA sequencing offers the potential to non-invasively identify a wide range of infections throughout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad356001f1f3ae7cbff8fa0e8ded5ea
https://doi.org/10.1038/s41564-018-0349-6
https://doi.org/10.1038/s41564-018-0349-6
Autor:
Igor D. Vilfan, Minna M. Poranen, Bojk A. Berghuis, David Dulin, Martin Depken, Susanne Hage, Dennis H. Bamford, Nynke H. Dekker
Publikováno v:
Cell Reports, Vol 10, Iss 6, Pp 983-992 (2015)
Cell Reports, 10 (6), 2015
Cell Reports, 10 (6), 2015
SummaryRNA viruses have specific mutation rates that balance the conflicting needs of an evolutionary response to host antiviral defenses and avoidance of the error catastrophe. While most mutations are known to originate in replication errors, diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c80026719c8fc530df660b7f6f2a096
http://www.sciencedirect.com/science/article/pii/S221112471500056X
http://www.sciencedirect.com/science/article/pii/S221112471500056X
Publikováno v:
Biopolymers. 87:141-148
DNA in solution can be condensed into dense aggregates by multivalent counterions. Here we investigate the effect of a nearby surface on the morphology of DNA condensates. We show that, contrary to what has often been assumed, interactions between DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b603ce420887fa97d934cd249a11fe25
https://doi.org/10.1002/bip.20806
https://doi.org/10.1002/bip.20806
Autor:
Igor D. Vilfan, David Dulin, Martin Depken, Nynke H. Dekker, Bojk A. Berghuis, Minna M. Poranen
Publikováno v:
Nucleic Acids Research
Transcription in RNA viruses is highly dynamic, with a variety of pauses interrupting nucleotide addition by RNA-dependent RNA polymerase (RdRp). For example, rare but lengthy pauses (>20 s) have been linked to backtracking for viral single-subunit R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec08d9c53ae1cf2efdfafa02d8c0263
https://pubmed.ncbi.nlm.nih.gov/26496948
https://pubmed.ncbi.nlm.nih.gov/26496948
Publikováno v:
Journal of Biological Chemistry. 279:20088-20095
The DNA of most vertebrate sperm cells is packaged by protamines. The primary structure of mammalian protamine I can be divided into three domains, a central DNA binding domain that is arginine-rich and amino- and carboxyl-terminal domains that are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be56c13e00f7bbda4b53b5d49e578f4d
https://doi.org/10.1074/jbc.m312777200
https://doi.org/10.1074/jbc.m312777200
Publikováno v:
Journal of Controlled Release. 86:361-370
To develop improved methods of gene delivery, packaging DNA in chemical or viral vectors could increase electroporation-mediated transfection. To test this hypothesis, electroporation was applied to DU145 prostate cancer cells incubated with green fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e92915a3375372bb4d80ba2f5a5e0fd
https://doi.org/10.1016/s0168-3659(02)00417-0
https://doi.org/10.1016/s0168-3659(02)00417-0
Autor:
Igor D. Vilfan, Samie R. Jaffrey, Yogesh Saletore, Kate D. Meyer, Jonas Korlach, Christopher E. Mason
Publikováno v:
Genome Biology
Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687e91859afffa8866df4288623dd7ce
https://pubmed.ncbi.nlm.nih.gov/23113984
https://pubmed.ncbi.nlm.nih.gov/23113984
Autor:
Tao Pan, Tyson A. Clark, Igor D. Vilfan, Qing Dai, Chengqi Yi, Stephen Turner, Jonas Korlach, Jeffrey Wegener, Yu-Chih Tsai
Publikováno v:
Journal of Nanobiotechnology
Background Zero-mode waveguides (ZMWs) are photonic nanostructures that create highly confined optical observation volumes, thereby allowing single-molecule-resolved biophysical studies at relatively high concentrations of fluorescent molecules. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f885fbe642278a7218ca8194a4c89ebc
https://pubmed.ncbi.nlm.nih.gov/23552456
https://pubmed.ncbi.nlm.nih.gov/23552456
Autor:
Igor D. Vilfan
Publikováno v:
Surface Science. 289:L604-L608
The nature of the transition between double-stepped and single-stepped structures of vicinal Si(001) surfaces is investigated theoretically. By using the transfer-matrix method and the elastic monopole and dipole step-step interactions, modified in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b5703b8310ea1e14587ac7373d7d44f
https://doi.org/10.1016/0039-6028(93)90877-m
https://doi.org/10.1016/0039-6028(93)90877-m