Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Igor Bonacossa-Pereira"'
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110501- (2022)
Summary: Axons experience significant strain caused by organismal development and movement. A combination of intrinsic mechanical resistance and external shielding by surrounding tissues prevents axonal damage, although the precise mechanisms are unk
Externí odkaz:
https://doaj.org/article/c62e9d7097c64402b72cb04af87f48f3
Spectrins are highly conserved molecules that form a distinct membrane associated periodic scaffold within axons thought to provide mechanical resilience. In C. elegans, UNC-70/ß-Spectrin also functions outside the nervous system, within the epiderm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73e2909db8f77b467b0b744c6f4aada
https://doi.org/10.1101/2022.09.07.507048
https://doi.org/10.1101/2022.09.07.507048
Publikováno v:
Cell reports. 38(10)
Axons experience significant strain caused by organismal development and movement. A combination of intrinsic mechanical resistance and external shielding by surrounding tissues prevents axonal damage, although the precise mechanisms are unknown. Her
Autor:
Marcelo F. Santiago, Fernanda Gubert, Igor Bonacossa-Pereira, Ana B. Decotelli, Andréia Vasconcelos-dos-Santos, Michelle Furtado, Rosalia Mendez-Otero
Publikováno v:
Brain research. 1712
Amyotrophic lateral sclerosis (ALS) is a chronic degenerative disease that mainly affects motor neurons, leading to progressive paralysis and death. Recently, cell therapy has emerged as a therapeutic alternative for several neurological diseases, in