Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Igor, de Farias Domingos"'
Autor:
Okeke Chinedu, Wouitchékpo Vincent Tonassé, Dulcinéia Martins Albuquerque, Igor de Farias Domingos, Aderson da Silva Araújo, Marcos André Cavalcanti Bezerra, Maria de Fátima Sonati, Magnun Nueldo Nunes dos Santos
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss 2, Pp 165-170 (2021)
Introduction: Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the H
Externí odkaz:
https://doaj.org/article/874eebcef95940afb6c1fe7c4b2627a6
Autor:
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 204-210 (2021)
Abstract Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD). NET
Externí odkaz:
https://doaj.org/article/7a2ac59c8d2740c2896aa4fa58dc8a97
Autor:
Vanessa Araujo Gomes Santaterra, Maiara Marx Luz Fiusa, Bidossessi Wilfried Hounkpe, Francine Chenou, Wouitchekpo Vincent Tonasse, Loredana Nilkenes Gomes da Costa, Diego Garcia-Weber, Igor de Farias Domingos, Franciele de Lima, Ivanio Teixeira Borba-Junior, Aderson da Silva Araújo, Antonio Roberto Lucena-Araújo, Marcos André Cavalcante Bezerra, Magnun Nueldo Nunes dos Santos, Fernando Ferreira Costa, Jaime Millán, Erich Vinicius De Paula
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Free extracellular heme has been shown to activate several compartments of innate immunity, acting as a danger-associated molecular pattern (DAMP) in hemolytic diseases. Although localized endothelial barrier (EB) disruption is an important part of i
Externí odkaz:
https://doaj.org/article/68ef82d31e9d4903aea19036d7c741a4
Autor:
Antonio R. Lucena-Araujo, Diego A Pereira-Martins, Rafael F. O. França, Igor de Farias Domingos, Pedro L Franca-Neto, Juan L Coelho-Silva, Aderson S Araujo, Isabel Weinhäuser, Marcos André Cavalcanti Bezerra
Publikováno v:
Annals of Hematology. 101:281-287
One of the physiologic mechanisms responsible to maintain asymmetric phospholipid distribution (in particular phosphatidylserine, PS) in human erythrocyte membranes is orchestrated by the balance between enzymes responsible for active transport of PS
Autor:
Manuela F. Hazin, Thais Helena Chaves Batista, Gabriela da Silva Arcanjo, Aderson S Araujo, Betânia Lucena Domingues Hatzlhofer, Antonio R. Lucena-Araujo, Diego Arruda Falcão, Jéssica Vitória Gadelha de Freitas Batista, Pablo Ramon Gualberto Cardoso, Maira Galdino da Rocha Pitta, Marcos André Cavalcanti Bezerra, Diego A Pereira-Martins, Igor de Farias Domingos, Fernando Ferreira Costa, Ana Claudia Mendonça dos Anjos, Isabel Weinhäuser
Publikováno v:
Annals of Hematology. 100:1921-1927
The clinical and phenotypic heterogeneity of patients with sickle cell anemia (SCA) is influenced by environmental and genetic factors. Several genetic modifiers, such as the KLOTHO (KL) gene, have been associated with SCA clinical outcomes. The KL g
Autor:
Magnun N. N. Santos, Okeke Chinedu, Igor de Farias Domingos, Aderson S Araujo, Maria de Fátima Sonati, Marcos André Cavalcanti Bezerra, Wouitchékpo Vincent Tonassé, Dulcineia M. Albuquerque
Publikováno v:
Hematology, Transfusion and Cell Therapy, Volume: 43, Issue: 2, Pages: 165-170, Published: 07 JUL 2021
Hematology, Transfusion and Cell Therapy, Vol 43, Iss 2, Pp 165-170 (2021)
Hematology, Transfusion and Cell Therapy
Hematology, Transfusion and Cell Therapy, Vol 43, Iss 2, Pp 165-170 (2021)
Hematology, Transfusion and Cell Therapy
Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the He
Autor:
Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Antonio R. Lucena-Araujo, Flávia Peixoto Albuquerque, Isabela Cristina Cordeiro Farias, Danízia Menezes de Lima Silva, Diego A Pereira-Martins, Manuela Albuquerque de Melo, Bruna Vasconcelos de Ancântara, Gabriela da Silva Arcanjo, Diego Arruda Falcão, Ana Claudia Mendonça dos Anjos, A. S. Araújo, Magnun N. N. Santos, Rodrigo Marcionilo Santana, Thais Helena Chaves Batista, Isabel Weinhäuser, Jéssica Vitória Gadelha de Freitas Batista, Betânia Lucena Domingues Hatzlhofer, Ana Beatriz Lucas de Moura Rafael, Luana Priscilla Laranjeira Prado, Igor de Farias Domingos, Fernando Ferreira Costa, Marcos André Cavalcanti Bezerra, Juan L Coelho-Silva, Jéssica Maria Florencio Oliveira
Publikováno v:
Annals of Hematology. 100:921-931
Alpha thalassemia and beta-globin haplotype are considered classical genetic disease modifiers in sickle cell anemia (SCA) causing clinical heterogeneity. Nevertheless, their functional impact on SCA disease emergence and progression remains elusive.
Autor:
Gabriela da Silva Arcanjo, Antonio R. Lucena-Araujo, Marcondes José de Vasconcelos Costa Sobreira, Jéssica Vitória Gadelha de Freitas Batista, Aderson S Araujo, Igor de Farias Domingos, A. S. Araújo, Magnun N. N. Santos, Thais Helena Chaves Batista, Jéssica Maricelly Deodato de Oliveira, Marcos André Cavalcanti Bezerra, Fernanda Silva Medeiros, Diego A Pereira-Martins, Diego Arruda Falcão, Flávia Peixoto Albuquerque, Ana Claudia Mendonça dos Anjos, Manuela F. Hazin, Dulcineia M. Albuquerque, Luana Priscilla Morais Laranjeira, Betânia Lucena Domingues Hatzlhofer, Fernando Ferreira Costa, Rodrigo Marcionilo Santana
Publikováno v:
Annals of Hematology. 100:903-911
Hyperbilirubinemia in patients with sickle cell anemia (SCA) as a result of enhanced erythrocyte destruction, lead to cholelithiasis development in a subset of patients. Evidence suggests that hyperbilirubinemia may be related to genetic variations,
Autor:
Adriana Malheiro, Nelson Abrahim Fraiji, Marcos André Cavalcanti Bezerra, Magnun N. N. Santos, Pedro Vieira da Silva Neto, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Bidossessi Wilfried Hounkpe, Francine Chenou, Antonio R. Lucena-Araujo, Erich Vinicius De Paula, Fernando Ferreira Costa, Igor de Farias Domingos
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 204-210 (2021)
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis
Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD). NETosis is a
Autor:
Daniela Pinheiro Leonardo, Magnun N. N. Santos, Erich Vinicius De Paula, Maria de Fátima Sonati, Dulcineia M. Albuquerque, Maria Heloisa Souza Lima Blotta, Igor de Farias Domingos, F. F. Costa, Marcos André Cavalcanti Bezerra, Francine Chenou, Aderson S Araujo
Publikováno v:
Biochemical Genetics. 58:580-594
The impaired bioavailability of endogenous nitric oxide (NO) in sickle cell anemia (SCA) may be influenced by polymorphisms in the endothelial nitric oxide synthase gene (eNOS). We compared allelic/genotypic frequencies of the eNOS polymorphisms T-78