Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Igor, Manzhulo"'
Autor:
Wen-Han Chuang, Evgeny Pislyagin, Liang-Yu Lin, Ekaterina Menchinskaya, Oleg Chernikov, Valery Kozhemyako, Tatiana Gorpenchenko, Igor Manzhulo, Elena Chaikina, Irina Agafonova, Alexandra Silchenko, Sergey Avilov, Valentin Stonik, Shey-Cherng Tzou, Dmitry Aminin, Yun-Ming Wang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeutic option against sol
Externí odkaz:
https://doaj.org/article/c6bbb407f8f7413c956ec9ab55bac05d
Autor:
Arina Ponomarenko, Anna Tyrtyshnaia, Darya Ivashkevich, Ekaterina Ermolenko, Inessa Dyuizen, Igor Manzhulo
Publikováno v:
Marine Drugs, Vol 20, Iss 8, p 538 (2022)
At present, the study of the neurotropic activity of polyunsaturated fatty acid ethanolamides (N-acylethanolamines) is becoming increasingly important. N-docosahexaenoylethanolamine (synaptamide, DHEA) is a highly active metabolite of docosahexaenoic
Externí odkaz:
https://doaj.org/article/2c85ef401c1f4d14bb23310cc287662c
Autor:
Igor Manzhulo, Olga Manzhulo, Anna Tyrtyshnaia, Arina Ponomarenko, Sophia Konovalova, Ekaterina Ermolenko, Elena Milkina, Anna Starinets
Publikováno v:
Brain Sciences, Vol 11, Iss 12, p 1561 (2021)
The present study demonstrates that synaptamide (N-docosahexaenoylethanolamine), an endogenous metabolite of docosahexaenoic acid, when administered subcutaneously (4 mg/kg/day, 14 days), exhibits analgesic activity and promotes cognitive recovery in
Externí odkaz:
https://doaj.org/article/74213d87f4f8440daa32c166d7208610
Autor:
Anna Tyrtyshnaia, Igor Manzhulo, Polina Mischenko, Anastasia A. Egoraeva, Sergey P. Kasyanov, Arina Ponomarenko
Publikováno v:
Cells Tissues Organs. 211:30-40
Marine organisms are among the prominent and abundant sources of 1-O-alkyl-sn-glycerols, including chimyl alcohol (CA), batyl alcohol and selachyl alcohol. These biologically active compounds are precursors in plasmalogen and phospholipid biosynthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d771e704c450176e28d06c042a8371db
https://doi.org/10.1159/000519832
https://doi.org/10.1159/000519832
Autor:
Anna, Tyrtyshnaia, Sophia, Konovalova, Arina, Ponomarenko, Anastasia, Egoraeva, Igor, Manzhulo
Publikováno v:
Nutrients. 14(18)
Neuroinflammation plays a critical role in the pathogenesis of most neurological and neurodegenerative diseases and therefore represents a potential therapeutic target. In this regard, accelerating the resolution process in chronic neuroinflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::821e2e8097c2dc25a1e5d235231d0c96
https://pubmed.ncbi.nlm.nih.gov/36145255
https://pubmed.ncbi.nlm.nih.gov/36145255
Autor:
Evgeny A. Pislyagin, Igor Manzhulo, I. V. Dyuizen, Arina I Ponomarenko, Ruslan M. Sultanov, Anna A. Tyrtyshnaia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
At present, there is a growing interest in the study of the neurotropic activity of polyunsaturated fatty acids ethanolamides (N-acylethanolamines). N-docosahexaenoylethanolamine (DHEA, synaptamide) is an endogenous metabolite and structural analogue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1811ff945baaa1a24c7920108c8c78b4
https://doaj.org/article/34d6c21ccf6c4caa8e88f516cc1c347a
https://doaj.org/article/34d6c21ccf6c4caa8e88f516cc1c347a
Autor:
Igor Manzhulo, Anna A. Tyrtyshnaia
Publikováno v:
Journal of Pain Research. 13:345-354
Introduction Neuropathic pain manifests in a diverse combination of sensory symptoms and disorders of higher nervous activity, such as memory deficiency, anxiety, depression, anhedonia, etc. This suggests the participation of brain structures, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac35c3f479f5a9069d531d417034ae20
https://doi.org/10.2147/jpr.s238458
https://doi.org/10.2147/jpr.s238458
Autor:
Igor Manzhulo, I. V. Dyuizen, Olga Manzhulo, Sergey P. Kasyanov, Anna Starinets, Anna A. Tyrtyshnaia
Publikováno v:
Neurochemical Journal. 14:101-107
—The analgesic and neuroprotective activity of docosahexaenoic acid (DHA, 22:6 n-3) was studied in a model of rat chronic constriction injury of the sciatic nerve. We characterized the morphological and chemical state of the distal sciatic nerve se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abbcae6159de11820508e1b6016c3212
https://doi.org/10.1134/s1819712420010158
https://doi.org/10.1134/s1819712420010158
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6273
N-docosahexaenoylethanolamine (DHEA), or synaptamide, is an endogenous metabolite of docosahexaenoic acid (DHA) that exhibits synaptogenic and neurogenic effects. In our previous studies, synaptamide administration inhibited the neuropathic pain-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d66b09141b434b771ef933c3a14668b
https://doi.org/10.3390/ijms24076273
https://doi.org/10.3390/ijms24076273
Autor:
Sophia Konovalova, Ekaterina V. Ermolenko, Arina Ponomarenko, Igor Manzhulo, Elena Milkina, Olga Manzhulo, Anna Tyrtyshnaia, Anna Starinets
Publikováno v:
Brain Sciences; Volume 11; Issue 12; Pages: 1561
Brain Sciences
Brain Sciences, Vol 11, Iss 1561, p 1561 (2021)
Brain Sciences
Brain Sciences, Vol 11, Iss 1561, p 1561 (2021)
The present study demonstrates that synaptamide (N-docosahexaenoylethanolamine), an endogenous metabolite of docosahexaenoic acid, when administered subcutaneously (4 mg/kg/day, 14 days), exhibits analgesic activity and promotes cognitive recovery in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987d1d768aee1cfb8359cd7213aff24b